As a work from home secretary, you perform administrative and clerical tasks for a company remotely. Your duties may involve answering phone calls and emails, arranging meetings and organizing the schedule, addressing bills, communicating with vendors, ordering supplies, creating reports, maintaining databases, and performing basic bookkeeping. Your responsibilities may also involve assisting staff members with a variety of tasks that you can complete remotely. A work from home secretary spends a significant amount of time on the computer. Unlike a virtual assistant, a work from home secretary typically has one employer and focuses on helping the company rather than an individual.