A work from home RN typically performs work such as providing patients with health care assessments, answering questions about medical conditions or treatments, and providing them with referrals if they should require further medical advice. Other telecommute RNs have case management responsibilities and follow their patients’ cases to ensure they receive the proper care. As a work from home RN, you may also teach online, and your duties in this case include leading lectures, grading quizzes and tests, and providing advice to students.