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The Senior Project Management Lead is a critical member of the Portfolio Management Office (PMO), supporting site-wide projects across the Thousand Oaks portfolio. This role ensures the timely and reliable supply of products to patients while delivering value to shareholders by driving operational excellence, enabling continuous improvement, and supporting site growth. The Senior Project Management Lead champions Takeda's Project Management Methodology (PMM) and PMO processes, applying strong project leadership and management capabilities to oversee projects of varying scope, scale, and complexity. They will guide initiatives through the full project lifecycle, ensuring successful delivery on time, within scope, and within budget.

How you will contribute

PMO Leadership

• Ensure consistent use of Takeda's Project Management Methodology (PMM) and support the site's Project Portfolio Life Cycle Management (LCM) system.
• Monitor project and portfolio performance using PM tools, driving timely interventions and problem solving.
• Review phasegate deliverables to ensure quality and readiness.
• Train and coach project teams, sponsors, and steering committees on PM best practices and tools.
• Improve project management processes by applying lessons learned and key performance indicators (KPIs).
• Help connect site strategy to project execution across the portfolio.

Project Management

• Lead crossfunctional teams through all phases of the project lifecycle to deliver scope, schedule, budget, quality, and compliance targets.
• Manage core project planning and controls, including resources, costs, schedules, risk mitigation, communications, and documentation.
• Support project prioritization and contribute to strategic portfolio processes.
• Adjust plans proactively, escalate risks, and remove barriers to keep projects on track.
• Maintain clear stakeholder alignment and communicate status and escalations to sponsors and senior leadership.
• Operate independently while managing a diverse project workload.
• Perform additional duties as needed to support site goals.

Time Allocation

• 60% Project Management
• 10% PMO / Governance Support
• 10% Program Strategy Support
• 10% Training, Development & Site Activities
• 10% Flex / Other Duties

Education & Experience

• Bachelor's degree in science, engineering, or related technical field preferred.
• 10+ years of project management experience leading complex crossfunctional and technical projects (process, equipment, commissioning/validation, infrastructure, facilities, utilities, IT, digital).
• 5+ years of project management experience in the pharmaceutical or biotech (cGMP) industry.
• PMP certification preferred; Lean/Six Sigma certification preferred.

Skills & Experience

• Strong multiproject management capability using formal PM methodologies.
• Experience leading projects in pharmaceutical/biotech regulated (cGMP) environments.
• Proficiency with key business and project management software (Microsoft Office, Project, Teams, PowerBI; Ariba/SAP/Veeva/TrackWise a plus).
• Excellent communication, facilitation, and stakeholdermanagement skills.
• Strong business acumen, attention to detail, and sound decisionmaking.
• Ability to influence, drive change, and lead crossfunctional teams without direct authority.
• Strategic thinker with strong problemsolving skills and commitment to quality.
• Knowledge of regulatory standards (GxP, FDA, ISPE, GAMP, ASTM E2500).

Physical Requirements

• Mix of office work and onfloor presence within the facility.
• Occasional ladder climbing; ability to lift up to 25 lbs.

Working Environment

• Standard office environment with frequent crossfunctional interaction.
• Fastpaced work with high expectations for timely execution.
• Occasional use of PPE or cleanroom garments.
• May require afterhours, oncall, or weekend availability to support project needs.

• Comprehensive Healthcare: Medical, Dental, and Vision

• Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan

• Health & Wellness programs including onsite flu shots and health screenings

• Generous time off for vacation and the option to purchase additional vacation days

• Community Outreach Programs and company match of charitable contributions

• Family Planning Support

• Flexible Work Paths

• Tuition reimbursement

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

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Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

U.S. Base Salary Range:

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Job Exempt