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Weekend Prn Rn Jobs in Sioux Falls, SD (NOW HIRING)

Interim HealthCare

Registered Nurse

Flandreau, SD · On-site

$45 - $47/hr

PRN / Part-Time / Full-Time Contract Registered Nurse (RN) opportunities * Shift options of DAYS / EVES / NOC, 8 HOUR SHIFTS / 10 HOUR SHIFTS / 12 HOUR SHIFTS * 24/7 contact with on-call staff member ...

TNAA TotalMed RN

Travel Nurse RN - Clinic

Sioux Falls, SD · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

Clinic * Discipline: RN * Duration: 13 weeks * 40 hours per week * Shift: 8 hours, days ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

New

TNAA TotalMed RN

Travel Nurse RN - Clinic

Sioux Falls, SD · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

Clinic * Discipline: RN * Duration: 13 weeks * 40 hours per week * Shift: 8 hours, days ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

New

Aveanna Healthcare

Registered Nurse (RN)

Larchwood, IA · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • PTO

Registered Nurse - RN Locations: Larchwood, Iowa Shifts: 10:00pm - 6:00am, Sunday - Saturday Skills ... Flexible scheduling- full-time, part-time, or PRN. Days, nights, and weekend shifts- we will work ...

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All JobsPrn Rn JobsWeekend Prn Rn JobsWeekend Prn Rn Jobs in Sioux Falls, SD

Weekend Prn Rn information

See Sioux Falls, SD salary details

$18

$35

$51

How much do weekend prn rn jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for weekend prn rn in Sioux Falls, SD is $35.14, according to ZipRecruiter salary data. Most workers in this role earn between $28.03 and $40.53 per hour, depending on experience, location, and employer.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the most commonly searched types of Prn Rn jobs in Sioux Falls, SD? The most popular types of Prn Rn jobs in Sioux Falls, SD are:
What are popular job titles related to Weekend Prn Rn jobs in Sioux Falls, SD? For Weekend Prn Rn jobs in Sioux Falls, SD, the most frequently searched job titles are:
What job categories do people searching Weekend Prn Rn jobs in Sioux Falls, SD look for? The top searched job categories for Weekend Prn Rn jobs in Sioux Falls, SD are:
What cities near Sioux Falls, SD are hiring for Weekend Prn Rn jobs? Cities near Sioux Falls, SD with the most Weekend Prn Rn job openings:
Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Sioux Falls, SD as of August 2026, with employment types broken down into 4% As Needed, 59% Full Time, 15% Part Time, and 22% Contract. Highlights an 98% In-person, and 2% Remote job distribution, with an average salary of $73,091 per year, or $35.1 per hour.

Registered Nurse

Interim HealthCare

Flandreau, SD • On-site

$45 - $47/hr

Other

Posted 8 days ago

Job description

Who we are:
Interim HealthCare is America's leading provider of home care and healthcare staffing. As a family owned, women owned, and veteran owned business, we have been in Sioux Falls the past 34+ years, Brookings for the past 9+ years, and Fargo for the past 4+ years. We strive to hire caring and compassionate individuals who wish to make a difference in their community, through strong leadership and dedication to the health care field!
CREATE YOUR OWN SCHEDULE THROUGH OUR APP
Serving staffing partners in the Sioux Falls, Brookings, Yankton, Mitchell, Watertown, Aberdeen, Pierre, Sioux City, and numerous other rural locations.
Our Registered Nurses (RNs) enjoy:

  • Registered Nurse (RN) Pay Rate: $45-$47+ per hour - PAID WEEKLY!
  • PRN / Part-Time / Full-Time Contract Registered Nurse (RN) opportunities
  • Shift options of DAYS / EVES / NOC, 8 HOUR SHIFTS / 10 HOUR SHIFTS / 12 HOUR SHIFTS
  • 24/7 contact with on-call staff member within Interim HealthCare
  • Free Continued Education Credits
Registered Nurse (RN) job duties may include:
  • PRN and/or Contract Staffing in Long-Term Care Facilities, and/or Assisted Living Settings
  • Aide with daily activities
  • Pass medications, give treatments, provide wound care
  • Assist with ambulation, transfers and range of motion exercises
  • Check vitals
  • Observe patient for issues requiring a change in care, medication or medical equipment
Registered Nurse (RN) qualifications:
  • Active Registered Nurse (RN) license within South Dakota, or reciprocity/multi-state eligibility
  • Maintains required certification/qualifications and associated standards
  • Registered Nurse (RN) experience highly preferred
  • Must be 18 years of age

EEO:
Interim HealthCare is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.

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