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Weekend Prn Rn Jobs in Sioux Falls, SD (NOW HIRING)

Aveanna Healthcare

Registered Nurse (RN)

Harrisburg, SD · On-site

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Flexible scheduling- full-time, part-time, or PRN. Days, nights, and weekend shifts- we will work ...

Interim HealthCare

Registered Nurse

Flandreau, SD · On-site

$45 - $47/hr

PRN / Part-Time / Full-Time Contract Registered Nurse (RN) opportunities * Shift options of DAYS / EVES / NOC, 8 HOUR SHIFTS / 10 HOUR SHIFTS / 12 HOUR SHIFTS * 24/7 contact with on-call staff member ...

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All JobsPrn Rn JobsWeekend Prn Rn JobsWeekend Prn Rn Jobs in Sioux Falls, SD

Weekend Prn Rn information

See Sioux Falls, SD salary details

$18

$35

$51

How much do weekend prn rn jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for weekend prn rn in Sioux Falls, SD is $35.14, according to ZipRecruiter salary data. Most workers in this role earn between $28.03 and $40.53 per hour, depending on experience, location, and employer.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the most commonly searched types of Prn Rn jobs in Sioux Falls, SD? The most popular types of Prn Rn jobs in Sioux Falls, SD are:
What are popular job titles related to Weekend Prn Rn jobs in Sioux Falls, SD? For Weekend Prn Rn jobs in Sioux Falls, SD, the most frequently searched job titles are:
What job categories do people searching Weekend Prn Rn jobs in Sioux Falls, SD look for? The top searched job categories for Weekend Prn Rn jobs in Sioux Falls, SD are:
What cities near Sioux Falls, SD are hiring for Weekend Prn Rn jobs? Cities near Sioux Falls, SD with the most Weekend Prn Rn job openings:
Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Sioux Falls, SD as of August 2026, with employment types broken down into 4% As Needed, 59% Full Time, 15% Part Time, and 22% Contract. Highlights an 98% In-person, and 2% Remote job distribution, with an average salary of $73,091 per year, or $35.1 per hour.

Travel Medical Cardiopulmonary Stepdown RN

PRN Healthcare

Sioux Falls, SD • On-site

Contractor

Medical, Dental, Vision, Life, Retirement

Posted 2 days ago

New

Job description

PRN Healthcare is seeking a travel nurse RN Stepdown for a travel nursing job in Sioux Falls, South Dakota.

Job Description & Requirements
  • Specialty: Stepdown
  • Discipline: RN
  • Start Date: 09/08/2026
  • Duration: 13 weeks
  • 36 hours per week
  • Shift: 12 hours, nights
  • Employment Type: Travel

PRN Healthcare Job ID #1572612. Pay package is based on 12 hour shifts and 36 hours per week (subject to confirmation) with tax-free stipend amount to be determined. Posted job title: SDU RN

About PRN Healthcare

Our story starts with a 21-year-old CNA named Pete Hietpas. Pete was diligently working in eastern Wisconsin with a variety of staffing agencies, but something was missing. He loved caring for his patients, but felt that staffing agencies were exchanging compassion for competitiveness. He was determined to change that. As a result, he started Nurses PRN in 1995 to become a model for the healthcare staffing industry – being competitive in the marketplace, yet still maintaining a compassionate heart.


Over the years Nurses PRN grew and evolved as a nationwide healthcare staffing company, and therefore wanted to be more inclusive to all valued healthcare professionals: nurses, allied health, locum tenens, CNAs, and more. This lead to the introduction of PRN Healthcare, which is inclusive of Nurses PRN and all of our other healthcare divisions.


Our mission to create authentic, meaningful relationships with our healthcare professionals helps us set them up for success in their dream assignment, whether that be a travel contract, local contract, or per diem shift. This is all driven by the simple idea that better care for our healthcare workers, leads to better patient care – and this is all supported by a dedicated internal staff.


Our company culture is strongly backed by faith-based values and activities, to remind us that our success provides us the opportunity to serve and give back to our communities. This is the spirit of caregiving. This is PRN Healthcare.

Benefits
  • Weekly pay
  • Guaranteed Hours
  • Continuing Education
  • 401k retirement plan
  • Referral bonus
  • Employee assistance programs
  • Company provided housing options
  • Medical benefits
  • Dental benefits
  • Vision benefits
  • Life insurance
PRN Healthcare logo

About PRN Healthcare

Sourced by ZipRecruiter

As a result, he started Nurses PRN in 1995 to become a model for the healthcare staffing industry - being competitive in the marketplace, yet still maintaining a compassionate heart. Over the years Nurses PRN grew and evolved as a nationwide healthcare staffing company, and therefore wanted to be more inclusive to all valued healthcare professionals: nurses, allied health, locum tenens, CNAs, and more. This lead to the introduction of PRN Healthcare, which is inclusive of Nurses PRN and all of our other healthcare divisions. Our mission to create authentic, meaningful relationships with our healthcare professionals helps us set them up for success in their dream assignment, whether that be a travel contract, local contract, or per diem shift. This is all driven by the simple idea that better care for our healthcare workers, leads to better patient care - and this is all supported by a dedicated internal staff. Our company culture is strongly backed by faith-based values and activities, to remind us that our success provides us the opportunity to serve and give back to our communities.

Industry

Recruiting and staffing services

Company size

501 - 1,000 Employees

Headquarters location

Appleton, WI, US

Year founded

1995

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