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Weekend Prn Rn Jobs in Sioux Falls, SD (NOW HIRING)

Aveanna Healthcare

Registered Nurse (RN)

Harrisburg, SD · On-site

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Flexible scheduling- full-time, part-time, or PRN. Days, nights, and weekend shifts- we will work ...

Interim HealthCare

Registered Nurse

Flandreau, SD · On-site

$45 - $47/hr

PRN / Part-Time / Full-Time Contract Registered Nurse (RN) opportunities * Shift options of DAYS / EVES / NOC, 8 HOUR SHIFTS / 10 HOUR SHIFTS / 12 HOUR SHIFTS * 24/7 contact with on-call staff member ...

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All JobsPrn Rn JobsWeekend Prn Rn JobsWeekend Prn Rn Jobs in Sioux Falls, SD

Weekend Prn Rn information

See Sioux Falls, SD salary details

$18

$35

$51

How much do weekend prn rn jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for weekend prn rn in Sioux Falls, SD is $35.14, according to ZipRecruiter salary data. Most workers in this role earn between $28.03 and $40.53 per hour, depending on experience, location, and employer.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN registered nurses have to work weekends?

PRN registered nurses are scheduled on an as-needed basis and are not typically required to work weekends unless assigned to weekend shifts. Their work schedule depends on the facility's staffing needs and the nurse's availability, often offering flexibility. However, some PRN positions may include weekend shifts if the facility requires coverage during those times.

What are the most commonly searched types of Prn Rn jobs in Sioux Falls, SD?

The most popular types of Prn Rn jobs in Sioux Falls, SD are:

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For Weekend Prn Rn jobs in Sioux Falls, SD, the most frequently searched job titles are:

What job categories do people searching Weekend Prn Rn jobs in Sioux Falls, SD look for?

The top searched job categories for Weekend Prn Rn jobs in Sioux Falls, SD are:

What cities near Sioux Falls, SD are hiring for Weekend Prn Rn jobs?

Cities near Sioux Falls, SD with the most Weekend Prn Rn job openings:

Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Sioux Falls, SD as of August 2026, with employment types broken down into 1% As Needed, 67% Full Time, 28% Part Time, 3% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $73,091 per year, or $35.1 per hour.

Travel Nurse RN - Med Surg

TNAA TotalMed RN

Sioux Falls, SD • On-site

Contractor

Medical, Dental, Vision, Retirement

Posted 22 days ago

Job description

TNAA TotalMed RN is seeking a travel nurse RN Med Surg for a travel nursing job in Sioux Falls, South Dakota.

Job Description & Requirements
  • Specialty: Med Surg
  • Discipline: RN
  • Duration: 13 weeks
  • 36 hours per week
  • Shift: 12 hours, rotating
  • Employment Type: Travel

We're looking for Medical Surgical RNs for an immediate travel nurse opening in Sioux Falls, SD. The right RN should have 1-2 years recent acute care experience. Read below for more requirements.
As a MedSurg RN, you will conduct patient assessments and prioritize data collection based on patients' immediate conditions or needs. MedSurg RNs perform ongoing assessments and appropriate treatments as ordered by a physician. Documenting patient findings and providing education and support to patients' families is essential to this travel nurse position.
As a Medical Surgical Travel Nurse, you should be prepared to perform the following tasks:

  • Provide bedside care for a variety of patients, including pre- and post-op patients.
  • Prepare, administer and record prescribed medication, reporting any adverse reactions to treatment.
  • Change dressings, insert catheters and start IVs.
  • Prepares equipment and aids physician during examination and treatment of patient.
  • Educates patients on surgical procedures.
  • Participates in discharge planning and initiates patient education plan as prescribed by physician.
Medical Surgical Travel Nurses should be able to stand and walk for long periods of time, as well as bend, lean and stoop without difficulty. RNs should be able to easily lift 20 pounds. Moving or lifting of patients may require lifting of up to 50 pounds at times. RNs will work in a fast-paced environment treating patients that may be confused, agitated, and/or uncooperative.
Requirements*: BLS, 2 Years
* Additional certifications may be required before beginning an assignment.

TNAA TotalMed RN Job ID #1480354. Pay package is based on 12 hour shifts and 36.0 hours per week (subject to confirmation) with tax-free stipend amount to be determined. Posted job title: Medical/Surgical - MedSurg RN - Travel Nurse

About TNAA TotalMed RN

TotalMed is a Top Ten, travel nursing and healthcare staffing agency with the mission of igniting purpose in healthcare. The organization staffs nurses, therapists, pharmacists, and other clinicians of all specialties in all 50 states. They offer local and travel jobs and match caregivers with the right organization to assist both facilities and patients. As an organization, they focus on putting highly-skilled staff into facilities to ensure adequate staffing for a better patient experience.


TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and permanent positions across the country in Nursing and Allied Health. Throughout 2020, the organization filled roles at even the most short-staffed facilities during the most challenging time in healthcare. By matching the right travel healthcare professional with the right organization, TotalMed continues to offer a lifeline to facilities and their patients.

Benefits
  • Weekly pay
  • Guaranteed Hours
  • Continuing Education
  • 401k retirement plan
  • Sick pay
  • Wellness and fitness programs
  • Referral bonus
  • Employee assistance programs
  • Medical benefits
  • Dental benefits
  • Vision benefits
  • Benefits start day 1
Travel Nurse Across America logo

About Travel Nurse Across America

Sourced by ZipRecruiter

Travel Nurse Across America (TNAA) is a leading healthcare staffing firm headquartered in North Little Rock, Arkansas, USA. Their primary focus lies within the healthcare industry, specializing in providing travel nurses for medical facilities across the country. Founded in 1999, TNAA has thrived over the years by maintaining an unwavering dedication to quality service, reliability, and personalized care for both the clients and the teams they contract. Their mission is driven by their commitment to improve the lives of the patients they serve by ensuring they're provided with the most highly skilled, caring, and dedicated healthcare professionals.

Industry

Recruiting and staffing services and health care and social assistance

Company size

201 - 500 Employees

Headquarters location

North Little Rock, AR, US

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