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Weekend Prn Rn Jobs in O Fallon, MO (NOW HIRING)

TNAA TotalMed RN

Travel Telemetry RN

Saint Louis, MO · On-site

$1.9K - $2.6K/wk

TNAA TotalMed RN is seeking a travel nurse RN Telemetry for a travel nursing job in Saint Louis ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

TNAA TotalMed RN

Travel Telemetry RN

Saint Peters, MO · On-site

$1.9K - $2.6K/wk

TNAA TotalMed RN is seeking a travel nurse RN Telemetry for a travel nursing job in Saint Peters ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

PRN Healthcare

Travel Telemetry RN

Saint Louis, MO · On-site

$1.9K - $2.6K/wk

PRN Healthcare is seeking a travel nurse RN Telemetry for a travel nursing job in St. Louis, Missouri. & Requirements * Specialty: Telemetry * Discipline: RN * Start Date: 09/21/2026 * Duration: 13 ...

PRN Healthcare

Travel Telemetry RN

Saint Peters, MO · On-site

$1.9K - $2.6K/wk

PRN Healthcare is seeking a travel nurse RN Telemetry for a travel nursing job in St. Peters, Missouri. & Requirements * Specialty: Telemetry * Discipline: RN * Start Date: 09/08/2026 * Duration: 13 ...

PRN Healthcare

Travel Telemetry RN

Saint Louis, MO · On-site

$1.9K - $2.6K/wk

PRN Healthcare is seeking a travel nurse RN Telemetry PCU - Progressive Care Unit for a travel nursing job in St. Louis, Missouri. & Requirements * Specialty: Telemetry PCU - Progressive Care Unit

PRN Healthcare

Travel Oncology RN

Saint Louis, MO · On-site

$2.0K - $2.7K/wk

PRN Healthcare is seeking a travel nurse RN Oncology for a travel nursing job in St. Louis, Missouri. & Requirements * Specialty: Oncology * Discipline: RN * Start Date: 09/28/2026 * Duration: 13 ...

PRN Healthcare

Travel Oncology RN

Saint Louis, MO · On-site

$2.0K - $2.7K/wk

PRN Healthcare is seeking a travel nurse RN Oncology for a travel nursing job in St. Louis, Missouri. & Requirements * Specialty: Oncology * Discipline: RN * Start Date: 09/28/2026 * Duration: 13 ...

PRN Healthcare

Travel OR RN

Saint Louis, MO · On-site

PRN Healthcare is seeking a travel nurse RN OR - Operating Room for a travel nursing job in St. Louis, Missouri. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Start Date: 09/28 ...

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All JobsPrn Rn JobsWeekend Prn Rn JobsWeekend Prn Rn Jobs in O'Fallon, MO

Weekend Prn Rn information

See O Fallon, MO salary details

$18

$34

$50

How much do weekend prn rn jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for weekend prn rn in O'Fallon, MO is $34.12, according to ZipRecruiter salary data. Most workers in this role earn between $27.21 and $39.38 per hour, depending on experience, location, and employer.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN registered nurses have to work weekends?

PRN registered nurses are scheduled on an as-needed basis and are not typically required to work weekends unless assigned to weekend shifts. Their work schedule depends on the facility's staffing needs and the nurse's availability, often offering flexibility. However, some PRN positions may include weekend shifts if the facility requires coverage during those times.

What cities near O'Fallon, MO are hiring for Weekend Prn Rn jobs?

Cities near O'Fallon, MO with the most Weekend Prn Rn job openings:

Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in O'Fallon, MO as of August 2026, with employment types broken down into 1% As Needed, 66% Full Time, 30% Part Time, 2% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $70,970 per year, or $34.1 per hour.

Registered Nurse (RN) PRN Tier 1

Select Medical

Bridgeton, MO

$45.50/hr

Per diem

Life, Retirement

Re-posted 10 days ago

Job description

SSM Health Rehabilitation Hospital 
A joint venture with Select Medical
Position: Registered Nurse (RN)
Location: Bridgeton, MO 
Schedule: PRN Tier 1 -  Day or Night 6:45-7:15

PRN Tier 1 Requirement: 4 shifts in a 6 week period, 1 must be weekend shift (Sat/Sun) and 1 minor holiday
Compensation: $45.50/PRN Tier 1 Rate hourly + $5.50 night diff and $3 weekend diff

Sign-On Bonus: $5,000 NO COMMITMENT/REPAYMENT

Our inpatient rehabilitation hospital is committed to providing exceptional and compassionate care to best address the medical, physical, emotional and vocational challenges for individuals with brain injuries, spinal cord injuries, neurological disorders, orthopedic issues, amputation and multiple traumas. 

Why Join Us:

  • Start Strong: Extensive orientation program to ensure a smooth transition into our setting.
  • Opportunity for Advancement: Demonstrate your skills and dedication which could lead to potential full-time opportunities
  • Foster Well-being: We offer benefits which support the financial, work/life and emotional well-being of you and your family members.  Part time/Per Diem positions are eligible for 401k based on reaching 1,000 hours within their first anniversary or subsequent calendar year. We also offer our employee assistance program to part time employees.
  • Your Impact Matters: Join a team of over 44,000 committed to providing exceptional patient care

  • Receive admissions and/or transfers
  • Initial and ongoing systematic patient assessment
  • Timely and accurate documentation using EPIC
  • Interpret assessment/diagnostic data including labs and telemetry
  • Ensure medical orders are transcribed and processed accurately
  • Instruct and counsel patients/families

Minimum Qualifications:

  • Valid State RN license
  • At least one year of RN experience
  • BLS required at hire

Preferred Qualifications:

  • BSN or enrollment in a BSN program
  • Clinical experience

*Post offer employment testing (POETs) are completed as part of the onboarding process and are to be completed before an employee's first day of work.*


Equal Opportunity Employer/including Disabled/Veterans

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