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Weekend Prn Rn Jobs in High Ridge, MO (NOW HIRING)

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$17

$33

$49

How much do weekend prn rn jobs pay per hour?

As of Sep 10, 2026, the average hourly pay for weekend prn rn in High Ridge, MO is $33.31, according to ZipRecruiter salary data. Most workers in this role earn between $26.54 and $38.41 per hour, depending on experience, location, and employer.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN registered nurses have to work weekends?

PRN registered nurses are scheduled on an as-needed basis and are not typically required to work weekends unless assigned to weekend shifts. Their work schedule depends on the facility's staffing needs and the nurse's availability, often offering flexibility. However, some PRN positions may include weekend shifts if the facility requires coverage during those times.

What cities near High Ridge, MO are hiring for Weekend Prn Rn jobs?

Cities near High Ridge, MO with the most Weekend Prn Rn job openings:

Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in High Ridge, MO as of September 2026, with employment types broken down into 1% As Needed, 63% Full Time, 31% Part Time, 4% Contract, and 1% Nights. Highlights an 93% Physical, 1% Hybrid, and 6% Remote job distribution, with an average salary of $69,276 per year, or $33.3 per hour.

Registered Nurse (RN) - Spine & Pain, PRN

Saint Louis, MO • On-site

Mercy
Health Care and Social Assistance • 10K+ employees
Learn more about Mercyexternal

Other

Medical, Dental, Vision, Retirement, PTO

Re-posted 3 days ago

Mercy rating

6.5

Company rating: 6.5 out of 10

Based on 209 frontline employees who took The Breakroom Quiz

614th of 898 rated healthcare providers

Job description

Find your calling at Mercy! Utilizes the nursing process to provide patient care. Maintains professional accountability for provision of patient care for the assigned patients. Coordinates the patient care in conjunction with other departments. Maintains patient rights and confidentiality of patient information. Performs duties and responsibilities in a manner consistent with our mission, values, and Mercy Service Standards. Position Details: Registered Nurse (RN) - Spine & Pain Management (PRN)

Location: Mercy Clinic Southfork 10050 Kennerly Road, Suite 2400 St. Louis, MO 63128 

Join Mercy’s Spine & Pain Management team and play a vital role in delivering specialized, patient-centered care. This PRN RN opportunity offers a dynamic clinical environment where you’ll support advanced pain management treatments and make a meaningful impact on patients’ quality of life.

Primary Responsibilities

  • Prepare and assess patients, including pain evaluations, vitals, and medical history

  • Assist providers with spine and pain management procedures and treatments

  • Administer medications and injections; support IV therapy as needed

  • Monitor patients and respond to changes in condition

  • Coordinate care, including follow-ups, referrals, and patient education

  • Maintain accurate documentation and ensure compliance with clinical standards

  • Support a safe, efficient clinic environment and assist with lab/testing as needed

Qualifications
Education: Graduation from an accredited school of nursing. Knowledge of the principles and skills needed for nursing, care, examination, diagnostic and treatment room procedures. Knowledge of medications and their effects, patient education, principles to develop a self-care program, instruments and common safety practices.
Licensure: Current valid state license.
Experience: Not required.
Certifications: CPR certification or obtain within 90 days of employment.
Other: Skills, Knowledge, and Abilities: Skill in assisting and performing a variety of medical treatments and procedures. Ability to react calmly and effectively in emergency situations. Must be able to interpret, adapt and apply guidelines and policies. Must be able to communicate clearly and establish and maintain effective working relationships with patients, staff and the public. Basic computer terminal and keyboard skills, or the ability to learn these skills, in order to access information and enter clinical data. Equipment Used: Must be able to operate equipment normally related to the specialty of the clinic.

Why You’ll Love Working Here

Exceptional Benefits Starting Day One:

  • 401(k) with Employer Match – Invest in your future with confidence

  • Free Parking – Convenience that saves you time and money

  • Career Growth Opportunities – Advance your skills and grow within Mercy

Why Mercy?

From day one, Mercy offers outstanding benefits - including medical, dental, and vision coverage, paid time off, tuition support, and matched retirement plans for team members working 32+ hours per pay period.

Join a caring, collaborative team where your voice matters. At Mercy, you'll help shape the future of healthcare through innovation, technology, and compassion. As we grow, you'll grow with us.

keyword(s): Registered NurseRNOutpatientClinicPRN

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PandoLogic. Keywords: Registered Nurse (RN), Location: St. Louis, MO - 63110 , PL: 604108060

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About Mercy

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Our mission is clear. We bring to life a healing ministry through our compassionate care and exceptional service. At Mercy, we believe in careers that match the unique gifts of unique individuals - careers that not only make the most of your skills and talents, but also your heart.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Chesterfield, MO, US

Year founded

1827

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