1

Weekend Infusion Rn Jobs in Houston, TX (NOW HIRING)

Infusion RN/LVN (Part-Time)

Conroe, TX

$31.75 - $42/hr

We are seeking a skilled and compassionate Part-time RN - Infusion Nurse to join our CLS Health clinic in our North Houston area offices. The Infusion Nurse will be responsible for administering ...

Infusion RN

Houston, TX · On-site

$51K - $95K/yr

Unencumbered RN License in state of employment or multi-state license * Current CPR and BLS ... Occasional overtime may be required, and weekend shifts based on location hours and operational ...

Unencumbered RN License in state of employment or multi-state license * Current CPR and BLS ... Occasional overtime may be required, and weekend shifts based on location hours and operational ...

Infusion RN

Houston, TX · On-site

$51K - $95K/yr

Unencumbered RN License in state of employment or multi-state license * Current CPR and BLS ... Occasional overtime may be required, and weekend shifts based on location hours and operational ...

Infusion Nurse PRN

Katy, TX · On-site

$40 - $50/hr

  • Retirement

... as a Registered Nurse at your own level, on a flexible schedule, and with the recognition and ... Weekend and evening opportunities, in-home and facility based * One to one patient care * We ...

Infusion Nurse

Cypress, TX · On-site

$32.25 - $42.75/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Current RN license by the applicable state's Board of Nursing, in good standing. * RN degree ... Participation in an on-call rotation , nights and weekends included, providing as-needed support ...

Infusion Nurse

Cypress, TX

$32.25 - $42.75/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Current RN license by the applicable state's Board of Nursing, in good standing. * RN degree ... Participation in an on-call rotation , nights and weekends included, providing as-needed support ...

Infusion Nurse

Cypress, TX

$32.25 - $42.75/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Current RN license by the applicable state's Board of Nursing, in good standing. * RN degree ... Participation in an on-call rotation , nights and weekends included, providing as-needed support ...

Infusion Nurse

Cypress, TX · On-site

$32.25 - $42.75/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Current RN license by the applicable state's Board of Nursing, in good standing. * RN degree ... Participation in an on-call rotation , nights and weekends included, providing as-needed support ...

Infusion Nurse PRN

Katy, TX · On-site

$40 - $50/hr

  • Retirement

... Weekends and/or weekdays shifts available Weekend and evening opportunities, in-home and facility ... Current unrestricted RN license in state of Texas Minimum one (2) year of documented experience ...

INFUSION NURSE

Kingwood, TX · On-site

$32.25 - $42.75/hr

... registered nurse in a clinical setting preferred. * Critical care or outpatient/homecare infusion ... experience preferred. * Recent intravenous administration and catheter management experience.

Showing results 41-60

Weekend Infusion Rn information

See Houston, TX salary details

$11

$43

$78

How much do weekend infusion rn jobs pay per hour?

As of Aug 15, 2026, the average hourly pay for weekend infusion rn in Houston, TX is $43.89, according to ZipRecruiter salary data. Most workers in this role earn between $34.66 and $47.98 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Weekend Infusion RN position, and why are they important?

Weekend Infusion RNs require a current RN license, strong IV therapy skills, and experience in administering infusion medications safely. Familiarity with infusion pumps, electronic health records (EHR), and up-to-date certifications like Basic Life Support (BLS) or Advanced Cardiac Life Support (ACLS) are typically expected. Excellent organizational skills, compassionate bedside manner, and the ability to work independently are valuable soft skills in this setting. Mastery of these competencies ensures reliable, high-quality patient care during weekends when resources may be limited.

What is a Weekend Infusion RN?

A Weekend Infusion RN is a registered nurse who administers intravenous (IV) therapies, medications, and treatments to patients during weekends. They work in outpatient clinics, hospitals, or home health settings, ensuring safe and effective infusion therapy. Responsibilities include monitoring patients for reactions, maintaining IV access, and educating patients about their treatments. This role requires strong IV skills, attention to detail, and the ability to work independently. It is ideal for nurses seeking flexible weekend hours while providing critical care to patients requiring infusion services.

What are the typical responsibilities and work environment for a Weekend Infusion RN?

As a Weekend Infusion RN, you will primarily administer intravenous medications, monitor patients for side effects, and educate them about their treatment plans—often in outpatient clinics, specialty centers, or sometimes patients' homes. The work environment is usually focused and patient-centered, with collaboration between RNs, pharmacists, and physicians, especially for complex cases. Since the role is concentrated on weekends, you may work more independently and manage a smaller, more specialized patient load. This schedule offers flexibility and the opportunity to focus on building relationships with patients receiving ongoing infusion therapy.

Do infusion nurses get paid more?

Infusion nurses often earn higher wages compared to general nursing roles due to specialized skills in administering IV therapies and managing complex patient needs. Their compensation can also increase with experience, certifications, and working in high-demand settings or during overtime and weekend shifts. However, pay varies by location, employer, and individual qualifications.

What are the most commonly searched types of Infusion Rn jobs in Houston, TX?

The most popular types of Infusion Rn jobs in Houston, TX are:

What are popular job titles related to Weekend Infusion Rn jobs in Houston, TX?

For Weekend Infusion Rn jobs in Houston, TX, the most frequently searched job titles are:

What job categories do people searching Weekend Infusion Rn jobs in Houston, TX look for?

The top searched job categories for Weekend Infusion Rn jobs in Houston, TX are:

What cities near Houston, TX are hiring for Weekend Infusion Rn jobs?

Cities near Houston, TX with the most Weekend Infusion Rn job openings:

Infographic showing various Weekend Infusion Rn job openings in Houston, TX as of August 2026, with employment types broken down into 1% As Needed, 69% Full Time, 25% Part Time, 4% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $91,301 per year, or $43.9 per hour.

$31.75 - $42/hr

Part-time

Re-posted 16 days ago


CLS Health rating

6.9

Company rating: 6.9 out of 10

Based on 10 frontline employees who took The Breakroom Quiz


Job description

Description

About CLS Health

CLS Health is a growing healthcare system in Houston, Texas that is taking a different approach to healthcare. We are a physician-led healthcare group that focuses on providing patients with holistic, multispecialty care. We're a dynamic team on a mission to provide better healthcare options for Houstonians!


We are Looking for:

We are seeking a skilled and compassionate Part-time RN - Infusion Nurse to join our CLS Health clinic in our North Houston area offices. The Infusion Nurse will be responsible for administering intravenous (IV) therapies, medications, blood products, and other infusions to patients in a safe, efficient, and caring manner. This position requires a strong clinical background, excellent communication skills, and a commitment to providing high-quality patient care.


Responsibilities:

  • Proficiently and independently assesses, plans, implements, evaluates, and documents the daily care of assigned patients
  • Proficiently executes physician's orders for all assigned patients
  • Demonstrates critical thinking, creativity, and versatility in problem solving and handling complex situations
  • Monitor fluid tubes, check infusions and make sure that medications implemented are not counteracting each other or causing a patient harm
  • Perform venipuncture, accessed implanted ports, maintained peripheral IV lines
  • Administer medication. This included mixing medications and inserting IVs while maintaining safe environment
  • Safely administer blood and blood products
  • Assesses patient progress, collaborating with other nursing staff when needed, in accordance with the nursing process and established plan of care
  • Perform infusions and monitoring of patient's status throughout entire infusion as well as managed emergency reactions.
  • Effectively communicates with medical, clinical and clerical staff to ensure the efficient operations of the clinic.
  • Effectively communicates with patients and visitors to resolve inquiries.
  • Assures proper maintenance of clinical records in compliance with local, state and federal laws.
  • May travel to other CLS clinics as needed.
  • Performs related duties as required.



Requirements

  • Graduate of an accredited school of professional nursing with current Texas licensure.
  • B.S.N. Preferred
  • Three (3) to five (5) years of clinical experience with one (1) year experience in a home health agency, preferred.
  • Understands regulatory compliance with state and federal regulations
  • Adhere to HIPAA and maintain client confidentiality




What CLS Health employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


CLS Health logo

About CLS Health

Sourced by ZipRecruiter

Industry

Health care and social assistance

Company size

201 - 500 Employees

Headquarters location

Webster, TX, US

Year founded

2005