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Weekend Clinical Trial Rn Jobs in Tyler, TX (NOW HIRING)

TNAA TotalMed RN

Travel Trauma ICU RN

Tyler, TX · On-site

TNAA TotalMed RN is seeking a travel nurse RN Trauma ICU for a travel nursing job in Tyler, Texas ... clinicians of all specialties in all 50 states. They offer local and travel jobs and match ...

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Weekend Clinical Trial Rn information

See Tyler, TX salary details

$27

$58

$90

How much do weekend clinical trial rn jobs pay per hour?

As of Aug 20, 2026, the average hourly pay for weekend clinical trial rn in Tyler, TX is $58.91, according to ZipRecruiter salary data. Most workers in this role earn between $47.79 and $66.39 per hour, depending on experience, location, and employer.

What is a Weekend Clinical Trial RN?

Weekend Clinical Trial RNs are registered nurses who work primarily on weekends to support clinical research studies. Their responsibilities include administering investigational treatments, monitoring patient safety, collecting data, and ensuring protocol compliance. They collaborate with research teams, patients, and other healthcare providers to facilitate trials and maintain high standards of care. This role is crucial for studies that require continuous patient oversight and data collection outside of standard weekday hours.

What are some unique challenges of working as a Weekend Clinical Trial RN, and how can I prepare for them?

As a Weekend Clinical Trial RN, you may encounter challenges such as limited onsite support, managing urgent protocol issues, and balancing patient care with strict research timelines. Since weekends often have fewer staff members present, strong communication and problem-solving skills are essential. To prepare, familiarize yourself with study protocols in advance, establish clear lines of communication with the principal investigator and other team members, and ensure you are comfortable with electronic data capture systems. Being proactive and organized will help you provide excellent patient care while maintaining compliance with research requirements.

What are the key skills and qualifications needed to thrive as a Weekend Clinical Trial RN, and why are they important?

To thrive as a Weekend Clinical Trial RN, you need a current RN license, clinical nursing experience, and a solid understanding of Good Clinical Practice (GCP) guidelines. Familiarity with clinical trial management systems, electronic data capture (EDC) tools, and protocol documentation is typically required. Strong attention to detail, organizational skills, and effective communication are vital soft skills for coordinating with research teams and ensuring regulatory compliance. These skills and qualities are crucial for maintaining patient safety, data integrity, and adherence to study protocols during weekend trial operations.

What is the difference between Weekend Clinical Trial Rn vs Weekend Research Nurse?

AspectWeekend Clinical Trial RnWeekend Research Nurse
CredentialsRegistered Nurse (RN) license, clinical trial trainingRegistered Nurse (RN) license, research-specific training
Work EnvironmentClinical trial sites, hospitals, research facilitiesResearch centers, hospitals, clinical research units
Employer & IndustryPharmaceutical companies, research organizationsAcademic institutions, research organizations
Work ScheduleWeekend shifts, flexible hoursWeekend shifts, flexible hours

Both roles involve RN credentials and work in research settings, often during weekends. The main difference lies in the focus: Weekend Clinical Trial Rns primarily support clinical trial protocols, while Weekend Research Nurses may be involved in broader research activities. Both roles are essential in advancing clinical research and typically require similar certifications and work environments.

What cities near Tyler, TX are hiring for Weekend Clinical Trial Rn jobs?

Cities near Tyler, TX with the most Weekend Clinical Trial Rn job openings:

Weekend Clinical Trial Rn jobs near you
Infographic showing various Weekend Clinical Trial Rn job openings in Tyler, TX as of June 2026, with employment types broken down into 63% Full Time, 23% Part Time, and 14% Contract. Highlights an 77% Physical, 5% Hybrid, and 18% Remote job distribution, with an average salary of $122,535 per year, or $58.9 per hour.

Travel IMC RN - $1,566 per week

TNAA TotalMed RN

Tyler, TX • On-site

$1.5K/wk

Other

Medical, Dental, Vision, Retirement

Posted 9 days ago

Job description

TNAA TotalMed RN is seeking a travel nurse RN Intermediate Care for a travel nursing job in Tyler, Texas.

Job Description & Requirements
  • Specialty: Intermediate Care
  • Discipline: RN
  • Duration: 13 weeks
  • 36 hours per week
  • Shift: 12 hours, nights
  • Employment Type: Travel

We're looking for Progressive Care Unit RNs for an immediate travel nurse opening in Tyler, TX. The right RN should have 1-2 years recent acute care experience. Read below for more requirements.
As a PCU Travel Nurse, you will care for patients who require close monitoring and frequent assessment, but aren't unstable enough to need ICU care. Progressive Care Unit RNs will utilize computer equipment to monitor cardiac and other vital information, detecting any changes and thereby enabling intervention of life-threatening or emergency situations. Close observation is necessary as many PCU patients receive a significant amount of complex medications, sometimes through an intravenous line that may need to be adjusted or titrated. The PCU RN is sometimes also called a step-down nurse, and the PCU is also known as cardiac stepdown, medical stepdown, neuro stepdown, surgical stepdown and ER holding.
As a PCU Travel Nurse, you should be prepared to perform the following tasks:

  • Provide basic bedside care; stabilize critical cardiac patients.
  • Change dressings, insert catheters and start IVs.
  • Prepare, administer and record prescribed medication, reporting any adverse reactions to treatment.
  • Monitor and adjust specialized equipment used on patients, and interpret and record electronic displays.
  • Initiate corrective action whenever information from monitoring equipment shows adverse symptomatology.
PCU Travel Nurses should be able to stand and walk for long periods of time, as well as bend, lean and stoop without difficulty. RNs should be able to easily lift 20 pounds. Moving or lifting of patients may require lifting of up to 50 pounds at times. Because of the fast-paced environment, Progressive Care Unit RNs must possess good skills for coping with stress and be able to relate to people of all ages and backgrounds.
Requirements*: ACLS, BLS, 2 Years
* Additional certifications may be required before beginning an assignment.

TotalMed Travel Job ID #1466680. Pay package is based on 12 hour shifts and 36 hours per week (subject to confirmation) with tax-free stipend amount to be determined. Posted job title: Progressive Care Unit - PCU RN - Travel Nurse

About TNAA TotalMed RN

TotalMed is a Top Ten, travel nursing and healthcare staffing agency with the mission of igniting purpose in healthcare. The organization staffs nurses, therapists, pharmacists, and other clinicians of all specialties in all 50 states. They offer local and travel jobs and match caregivers with the right organization to assist both facilities and patients. As an organization, they focus on putting highly-skilled staff into facilities to ensure adequate staffing for a better patient experience.

TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and permanent positions across the country in Nursing and Allied Health. Throughout 2020, the organization filled roles at even the most short-staffed facilities during the most challenging time in healthcare. By matching the right travel healthcare professional with the right organization, TotalMed continues to offer a lifeline to facilities and their patients.

Why Vivian Health?

Be sure to apply via Vivian Health to increase your chances of landing your perfect job. Just complete your Vivian Health profileonce, and get access to thousands of opportunities across the country. Then keep up to date with your job application process and conversations with our easy to use app.

Benefits
  • Weekly pay
  • Guaranteed Hours
  • Continuing Education
  • 401k retirement plan
  • Sick pay
  • Wellness and fitness programs
  • Referral bonus
  • Employee assistance programs
  • Medical benefits
  • Dental benefits
  • Vision benefits
  • Benefits start day 1

Apply