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Vice President Cheminformatics Scientist Jobs (NOW HIRING)

VP, Toxicology

San Francisco, CA · On-site

$310K - $340K/yr

At Latigo, we value science, patient-focus, and innovation. Position Description: The Vice President of Toxicology will provide strategic and scientific leadership for all aspects of nonclinical ...

Vice President of Sales Location: Detroit, MI- Onsite Type: Full-time Security Clearance: No ... Oversee consultative, solution-based, and enterprise sales motions involving technical, scientific ...

This is a unique opportunity to work across scientific strategy, help shape our medical ... What You Should Have * VP: 10+ years of healthcare communications, medical affairs, or medical ...

Vice President, Engineering

Cambridge, MA · On-site

$196K - $253K/yr

Your Impact at LILA As Lila scales its AI Science Factories globally, the VP of Engineering will create and sustain an engineering model for a unified, scalable platform for autonomous ...

Vice President, Engineering

Cambridge, MA · On-site

$196K - $253K/yr

Your Impact at LILA As Lila scales its AI Science Factories globally, the VP of Engineering will create and sustain an engineering model for a unified, scalable platform for autonomous ...

The VP, Federal Policy will engage primarily with Congress, the White House, the Department of ... Preferred: * MBA degree Business Administration, Engineering, MPA, Political Science, Law Public ...

The VP, Federal Policy will engage primarily with Congress, the White House, the Department of ... Preferred: * MBA degree Business Administration, Engineering, MPA, Political Science, Law Public ...

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VP, Toxicology

Latigo Biotherapeutics

San Francisco, CA • On-site

$310K - $340K/yr

Full-time

Re-posted 14 days ago


Job description

Job Title: VP, Toxicology
Position Type: Full Time
Company Description:
Latigo Biotherapeutics, Inc. is a private, early-stage biotechnology company focused on discovering and developing the next generation of non-opioid medicines for pain and pain-related syndromes. Our mission is the development of novel therapies that transform the lives of patients. The company is headquartered in Thousand Oaks, CA and has a highly successful management team and an experiencedBoard of Directors. At Latigo, we value science, patient-focus, and innovation.
Position Description:
The Vice President of Toxicology will provide strategic and scientific leadership for all aspects of nonclinical safety and toxicology across Latigo's discovery and development pipeline. This role is accountable for defining and executing phase-appropriate nonclinical safety strategies to support candidate selection, IND-enabling activities, first-in-human (FIH) studies, and overall clinical development for small molecule programs.
As a recognized subject matter expert, the VP will serve as a core member of cross-functional project teams and a key contributor to regulatory strategy. This individual will oversee internal and external toxicology resources, mentor and develop nonclinical scientists, and ensure high scientific rigor, regulatory compliance, and efficient execution of nonclinical safety programs.
Key Responsibilities
Strategic & Scientific Leadership
  • Lead the overall nonclinical safety and toxicology strategy from early discovery through IND submission, clinical development, and NDA submission.
  • Serve as the toxicology and nonclinical safety SME on cross-functional project teams, providing clear risk-benefit assessments and strategic recommendations.
  • Define target safety profiles and guide compound progression decisions in partnership with Discovery, DMPK, Clinical Pharmacology, and Clinical Development teams.

Study Design & Execution
  • Design, oversee, and interpret IND-enabling toxicology and safety pharmacology studies, ensuring alignment with regulatory expectations and development timelines.
  • Provide scientific oversight of CROs, consultants, and vendors, including study design, protocol review, data quality, and final report approval.
  • Ensure nonclinical safety and toxicology programs are scientifically sound, efficiently executed, and appropriately staged for development phase.

Regulatory & Compliance
  • Partner closely with Regulatory Affairs to author, review, and approve nonclinical sections of INDs, IBs, briefing documents, and regulatory responses.
  • Support regulatory interactions (FDA and ex-US), including pre-IND, end-of-Phase 2, pre-NDA, and other regulatory meetings.
  • Ensure compliance with GLP, ICH, and FDA regulatory guidance applicable to nonclinical safety.

People & Organizational Leadership
  • Build, mentor, and develop a high-performing nonclinical safety team, fostering scientific excellence and collaborative culture.
  • Contribute to the evolution of nonclinical processes, standards, and best practices as the organization scales.
  • Act as a thought partner to senior R&D leadership on portfolio strategy and organizational capability development.

Qualifications & Experience
  • PhD, DVM, or equivalent in Toxicology, Pharmacology, or a related scientific discipline.
  • 15+ years of industry experience in nonclinical safety/toxicology within biotechnology or pharmaceutical settings.
  • Demonstrated leadership of toxicology programs for small molecule therapeutics from IND-enabling studies through marketing applications
  • Strong track record of regulatory authorship and agency interactions supporting early development programs.
  • Proven ability to lead cross-functional teams and influence development strategy at the program and portfolio level.
  • Experience in therapeutic areas related to pain or neuroscience is preferred.

Core Competencies
  • Deep scientific expertise in nonclinical safety and toxicology
  • Strategic thinking with strong execution focus
  • Clear, persuasive scientific communication
  • Collaborative leadership and people development
  • Comfort operating in a fast-paced, early-stage biotech environment