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Vertex Engineering Jobs in Boston, MA (NOW HIRING)

Lab Automation Engineer

Boston, MA · On-site

$85K - $128K/yr

This role will support multiple disease areas and advance automation capabilities within Vertex ... Typically requires a Bachelor's Degree in chemical engineering, computer sciences or related field ...

Senior Principal AI Engineer

Boston, MA · On-site

$136K - $187K/yr

... Vertex to create, integrate, customize, and operationalize their own agents using shared platform standards, tooling, and governance controls. The ideal candidate combines strong software engineering ...

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Vertex Engineering information

See Boston, MA salary details

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How much do vertex engineering jobs pay per hour?

As of Aug 14, 2026, the average hourly pay for vertex engineering in Boston, MA is $20.98, according to ZipRecruiter salary data. Most workers in this role earn between $17.50 and $22.74 per hour, depending on experience, location, and employer.

How does a Vertex Engineer typically collaborate with cross-functional teams during the product development lifecycle?

Vertex Engineers often work closely with product managers, designers, and software developers to ensure that product specifications are technically feasible and align with project goals. They participate in regular meetings to discuss design changes, troubleshoot issues, and integrate feedback from various stakeholders. Effective communication and a proactive approach to problem-solving are key, as Vertex Engineers frequently act as a bridge between engineering and other departments. This collaborative environment not only enhances product quality but also fosters professional growth through exposure to diverse perspectives and expertise.

What is the difference between Vertex Engineering vs Mechanical Engineering?

AspectVertex EngineeringMechanical Engineering
Required CredentialsBachelor's degree in engineering or related field, certifications varyBachelor's degree in Mechanical Engineering, Professional Engineer (PE) license often preferred
Work EnvironmentDesign, development, and testing of engineering systems, often in tech or manufacturing sectorsDesign, analysis, and manufacturing of mechanical systems, machinery, and tools
Employer & Industry UsageTech companies, manufacturing firms, engineering consultanciesAutomotive, aerospace, manufacturing, energy sectors

Vertex Engineering typically focuses on designing and developing engineering systems, often in technology or manufacturing contexts, requiring a background in engineering principles. Mechanical Engineering covers the design and analysis of mechanical systems and machinery, with a strong emphasis on physical principles and manufacturing processes. While both roles require engineering degrees, Vertex Engineering may involve more software and system integration, whereas Mechanical Engineering emphasizes mechanical design and analysis.

What are the key skills and qualifications needed to thrive as a Vertex Engineer?

To thrive as a Vertex Engineer, you need a solid background in computer graphics, 3D mathematics, and software development, often supported by a degree in computer science or engineering. Familiarity with graphics APIs (such as OpenGL, DirectX, or Vulkan), shader programming, and version control systems is typically required. Strong problem-solving abilities, attention to detail, and effective teamwork are valuable soft skills in this role. These competencies ensure the efficient creation and optimization of graphics pipelines, which are crucial for delivering high-performance visual applications.

Does Vertex Engineering have remote jobs?

Vertex Engineering offers some remote job opportunities, depending on the role and project requirements. Many positions may require on-site presence or hybrid work arrangements, and remote options are typically specified in the job listing. Candidates should review individual job postings for specific remote work availability.

What is Vertex Engineering?

Vertex Engineering typically refers to a specialized field within engineering that focuses on innovative solutions in areas such as mechanical, electrical, or civil engineering. Companies or teams with this title often work on complex projects that require advanced technical skills, problem-solving abilities, and the integration of cutting-edge technologies. The term 'Vertex' may also refer to a specific company name or a division within a larger organization. Overall, Vertex Engineering professionals are involved in designing, developing, and optimizing systems or structures to meet specific client or industry needs.

What are popular job titles related to Vertex Engineering jobs in Boston, MA?

For Vertex Engineering jobs in Boston, MA, the most frequently searched job titles are:

Infographic showing various Vertex Engineering job openings in Boston, MA as of August 2026, with employment types broken down into 88% Full Time, 6% Part Time, 5% Contract, and 1% Nights. Highlights an 87% Physical, 5% Hybrid, and 8% Remote job distribution, with an average salary of $43,645 per year, or $21 per hour.

Senior Director, Engineering and Materials Science

Vertex Pharmaceuticals

Boston, MA • On-site

$228K - $342K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 12 days ago


Vertex Pharmaceuticals rating

6.5

Company rating: 6.5 out of 10

Based on 5 frontline employees who took The Breakroom Quiz

78th of 86 rated pharmaceutical


Job description

Job Description
General Summary:
Vertex is seeking a talented individual to join the Engineering and Materials Science department in Boston, MA. The successful candidate will be a productive, results-oriented leader who is able to lead a diverse team of engineers and scientists and contribute to the successful development and scale-up of drug substance and drug product candidates. Excellent leadership, interpersonal, and organization skills as well as a high level of technical aptitude and creativity are required for success in this position.
Key Duties and Responsibilities:
  • Be responsible for leading and developing a cross-functional team of engineers and scientists in defining, developing, and demonstrating viable, multi-step syntheses for the robust manufacture of small-molecule or oligonucleotide active pharmaceutical ingredients, spanning all phases of clinical development through to commercialization and launch
  • Lead drug substance process development efforts and apply sound scientific judgement to drive multiple assets in a fast-paced environment via laboratory development, modeling, drug supply preparation, and technology transfer to third party manufacturing facilities
  • Collaborate with materials discovery, process chemistry, analytical development, and formulation groups to improve the overall discovery/development process for definition and optimization of drug substance properties and performance across the clinical development spectrum
  • Drive the adoption of process modeling within the department.
  • Potentially lead projects, representing all aspects of pharmaceutical sciences
  • Be at the forefront of industry best practices and promote innovation.
  • Be vested in developing team members and technically mentoring junior-level scientists
  • Influence departmental strategic direction
  • Use excellent communication and interpersonal skills to influence stakeholders and interact, lead, and collaborate within an interdisciplinary team comprised of chemical engineers, organic, physical, and analytical chemists, materials and solid-state scientists, and formulation development personnel

Knowledge and Skills:
  • Experience leading a team of engineers/scientists in pharmaceutical process development
  • Advanced knowledge of standard unit operations encountered in small molecule and/or Oligonucleotide drug substance process development inclusive of particle engineering, reaction kinetics, thermodynamics, and transport fundamentals
  • Have demonstrated experience with modeling complex, physicochemical systems, data analysis, statistical design of experiments, QbD concepts, and fluency with common physical property and process modeling tools
  • Demonstrated process scale up and regulatory dossier authoring.
  • Experience with process development and problem solving in a matrix environment
  • Strong communication skills and the ability to influence both stakeholders and team members

Education and Experience:
  • A BS (+ 20 years), MS (+ 15 years) or PhD (+ 11 years) in Materials Science/Chemistry, or a closely related field, with relevant pharmaceutical materials development experience
  • 5 years experience managing a team

#LI-BS1
Pay Range:
$228,000 - $342,000
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
On-Site Designated
Flex Eligibility Status:
In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Onsite
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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