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Vc Operating Partner Jobs in Waltham, MA (NOW HIRING)

... VC professionals. We believe our best work happens when we're together. AV operates as a 5-day-a ... The Director partners with managers to translate feedback into practical Individual Development ...

... VC professionals. We believe our best work happens when we're together. AV operates as a 5-day-a ... The Director partners with managers to translate feedback into practical Individual Development ...

... VC firms in the industrial and construction space. What We're Looking For We're looking for an Area ... Partner with Ops Engineering / training owners to ensure training and certification are completed ...

New

We invest across North America from our bases in NYC and Boston, partnering with visionary founders ... operators * You have an immense amount of hustle, the kind that gets you into the right rooms and ...

... by leading VC firms, including Tiger Global, Heal Partners, IceHouse Ventures, and Movac, and ... operator and educator to take full ownership of service execution--someone who builds the systems ...

Head of Service, Crimson Rise

Boston, MA ยท On-site +1

$640/day

... by leading VC firms, including Tiger Global, Heal Partners, IceHouse Ventures, and Movac, and ... operator and educator to take full ownership of service execution-someone who builds the systems ...

Backed by a16z speedrun, Patron, Kevin Hart, Pear VC, and founders of Instacart and Dreamworks ... Propose and prioritize improvements, then partner with engineering and design to execute them

Backed by a16z speedrun, Patron, Kevin Hart, Pear VC, and founders of Instacart and Dreamworks ... Propose and prioritize improvements, then partner with engineering and design to execute them

Backed by a16z speedrun, Patron, Kevin Hart, Pear VC, and founders of Instacart and Dreamworks ... Propose and prioritize improvements, then partner with engineering and design to execute them

Backed by a16z speedrun, Patron, Kevin Hart, Pear VC, and founders of Instacart and Dreamworks ... Propose and prioritize improvements, then partner with engineering and design to execute them

Senior Machine Learning Engineer

Boston, MA ยท On-site

$170K - $205K/yr

Partner cross-functionally with product, engineering, clinical, and compliance teams to define ... VC (PillPack), as well as angel investors such as Frederic Kerrest (Co-founder of Okta). Our work ...

Showing results 41-60

Vc Operating Partner information

See Waltham, MA salary details

$32.9K

$126.8K

How much do vc operating partner jobs pay per year?

As of Sep 4, 2026, the average yearly pay for vc operating partner in Waltham, MA is $122,023.00, according to ZipRecruiter salary data. Most workers in this role earn between $125,700.00 and $125,700.00 per year, depending on experience, location, and employer.

What is a VC Operating Partner?

VC Operating Partners are experienced executives who work within venture capital (VC) firms to support portfolio companies with operational expertise. Unlike traditional investors, they focus on helping startups scale by offering guidance on strategy, operations, recruiting, and growth. Their hands-on approach helps companies address challenges and seize opportunities more effectively, adding value beyond just financial investment. Operating Partners often have backgrounds in management, entrepreneurship, or specific industries relevant to the VC firm's focus.

How does a VC Operating Partner typically collaborate with portfolio companies to drive growth?

A VC Operating Partner works closely with portfolio company leadership teams, offering strategic guidance and hands-on operational support tailored to each company's needs. This often involves helping to refine business models, optimize go-to-market strategies, recruit key executives, and implement best practices in areas such as sales, marketing, and product development. The role requires balancing advisory input with actionable execution, while building strong relationships to earn the trust of founders and management teams. Collaboration is frequent and may include structured check-ins, on-site visits, and ongoing communication to ensure alignment and measurable progress.

What are the key skills and qualifications needed to thrive as a VC Operating Partner, and why are they important?

To thrive as a VC Operating Partner, you need extensive experience in business operations, strategic management, and scaled execution, often demonstrated by a track record in C-suite roles or successful entrepreneurship. Familiarity with financial modeling, portfolio management systems, and due diligence processes, along with an understanding of industry-specific metrics, is typically required. Exceptional leadership, communication, and mentoring skills distinguish top performers by enabling strong relationships with founders and portfolio companies. These abilities are crucial for driving growth, supporting investment success, and maximizing value creation within the venture capital ecosystem.

What is the difference between Vc Operating Partner vs Vc Associate?

AspectVc Operating PartnerVc Associate
Required CredentialsExperience in operations, industry expertise, often MBA or similarUndergraduate degree, some finance or business background
Work EnvironmentHands-on operational involvement, strategic guidanceResearch, due diligence, financial analysis
Employer & Industry UsagePrivate equity firms, venture capital firmsVenture capital firms, investment teams

The Vc Operating Partner typically has extensive operational experience and works closely with portfolio companies to improve performance. In contrast, a Vc Associate focuses on deal sourcing, due diligence, and supporting investment processes. While both roles are integral to venture capital firms, the Operating Partner is more involved in post-investment operational management, whereas the Associate is more involved in the early investment stages.

What cities near Waltham, MA are hiring for Vc Operating Partner jobs?

Cities near Waltham, MA with the most Vc Operating Partner job openings:

Infographic showing various Vc Operating Partner job openings in Waltham, MA as of August 2026, with employment types broken down into 1% As Needed, 76% Full Time, 20% Part Time, 2% Contract, and 1% Nights. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $122,023 per year, or $58.7 per hour.

(Senior) Director, Portfolio Strategy, Life Sciences

Lila Sciences

Cambridge, MA โ€ข On-site

Full-time

Medical, Dental, Vision, Life

Re-posted 9 days ago


Job description

Your Impact at LILA
Lila Sciences is hiring a Director / Senior Director, New Product Planning to help shape Lila Origins, our company and asset creation arm which partners to translate scientific vision into molecules, materials, and real-world ventures. As a member of a small, highly cross-functional team, you will bring the commercial voice to life sciences opportunities at the earliest stages, assessing where Lila's platform can produce differentiated assets and shaping how those opportunities become ventures, partnerships, or programs.
You will spend your time at the interface of science, market, and deal structure. You will match therapeutic modalities to disease areas based on biological fit, competitive landscape, and commercial viability. You will build quantitative views of opportunities (market sizing, patient population modeling, deal economics) and translate them into recommendations for Origins and Lila leadership. You will pressure-test ideas with external operators, investors, and partners, and use what you learn to sharpen Lila's Origins thesis.
This role suits someone who has run new product planning, asset strategy, or commercial assessment work inside a pharma or biotech organization, lives close to industry trends, and is drawn to a builder environment where the asset list is being defined in real time. You will work closely with the VP, Head of Lila Origins, and sit within Corporate Development. The work is high ambiguity, high leverage, and deliberately cross-disciplinary.
What You'll Be Building
  • Source and evaluate new life sciences opportunities for Origins, screening for scientific differentiation, commercial viability, and fit with Lila's platform capabilities
  • Track therapeutic area trends, modality breakthroughs, pipeline movement, and deal activity across pharma and biotech, and translate signal into actionable views for Origins
  • Match therapeutic modalities to disease areas using biological rationale, competitive landscape, and unmet need, and recommend where Origins should concentrate effort
  • Build and own market sizing, patient population, and deal economic models that inform go / no-go decisions on candidate ventures and partnerships
  • Develop target product profiles and early commercial theses for assets under consideration, in partnership with Science, Product, and Corporate Development
  • Run primary and secondary research (KOL interviews, competitor tracking, payer and clinician landscape) to stress-test assumptions and sharpen recommendations
  • Shape deal structures and partnership constructs alongside Corporate Development, translating commercial logic into terms that work for Lila and counterparties
  • Contribute to Origins' strategic thesis by synthesizing what we learn across opportunities into recommendations on therapeutic area focus, modality bets, and partnership models

What You'll Need to Succeed
  • 6-8+ years in new product planning, commercial assessment, asset strategy, or business development inside a pharma, biotech, or life sciences investor (VC, growth equity) setting, with a track record of shaping go / no-go calls on early assets
  • Strong scientific literacy in life sciences (therapeutics, modalities, disease biology); able to engage substantively with Science and external KOLs and translate scientific nuance into commercial implications
  • Demonstrated ability to match therapeutic modalities to disease areas, with a clear point of view on where biological fit, unmet need, and competitive landscape converge
  • Hands-on modeling experience: market sizing, patient population, forecasting, deal economics; comfortable building models from scratch and defending assumptions
  • Active fluency in industry trends, pipeline movement, and deal activity across pharma and biotech; reads the market without needing a research function to brief you
  • Strong written and verbal communication; able to distill complex commercial and scientific analyses into crisp recommendations for senior leadership
  • Comfort operating in high ambiguity with limited oversight; biased toward building structure where none exists

Bonus Points For
  • Advanced degree in life sciences (PhD, MS in biology, chemistry, bioengineering) or an MBA with deep life sciences focus
  • Network of biotech operators, VCs, KOLs, and pharma BD leaders that you can tap for diligence and signal
  • Hands-on use of AI tools in your workflows (market research, competitor tracking, modeling, synthesis) and a clear point of view on how AI is reshaping drug discovery and asset creation
  • Prior experience structuring or evaluating partnership models, joint ventures, or NewCo formation

Compensation
We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.
U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.
Expected Base Salary Range
$168,000-$272,000 USD
About LILA
Lila Sciences is building Scientific Superintelligenceโ„ข to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factoryโ„ข instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
We're All In
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.