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Variant Jobs in California (NOW HIRING)

Exactsciences

Sr Product Owner

San Diego, CA · On-site

Experience withrulesdrivenworkflows, shared biomarker/variant knowledgebases, and multiproduct report generation platforms in a regulated clinical environment. * Comfortoperatingunder CLIA/CAP/FDA ...

Exact Sciences

Sr Product Owner

San Diego, CA · On-site

Understand end-to-end sample to answer workflows, including bioinformatics output, variant curation, interpretation, and report workflows, including bioinformatics output, variant curation ...

Exact Sciences

Sr Product Owner

San Diego, CA · On-site

Understand end-to-end sample to answer workflows, including bioinformatics output, variant curation, interpretation, and report workflows, including bioinformatics output, variant curation ...

EdenRoc Sciences

Scientific Sales, Oncology

San Diego, CA · On-site

$80K - $120K/yr

This role will support our genomic variant products and services business unit-directly targeting cancer applications for market growth. Candidates with prior sales experiences selling NGS-based ...

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All JobsVariant JobsVariant Jobs in California

Variant information

See California salary details

$10

$21

$31

How much do variant jobs pay per hour?

As of Jun 9, 2026, the average hourly pay for variant in California is $21.01, according to ZipRecruiter salary data. Most workers in this role earn between $16.59 and $23.03 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Variant Analyst, and why are they important?

To thrive as a Variant Analyst, you need a solid understanding of genetics, molecular biology, and bioinformatics, often supported by a relevant degree in life sciences or computational biology. Familiarity with genomic analysis tools (like GATK, ANNOVAR), databases (ClinVar, gnomAD), and scripting languages such as Python or R is typically required. Strong attention to detail, analytical thinking, and effective communication help distinguish top performers in this role. These competencies are crucial for accurately interpreting genetic variants, ensuring reliable results, and collaborating with multidisciplinary teams in clinical or research settings.

What are variant jobs?

Variant jobs typically refer to roles within companies that focus on genetic variant analysis, such as bioinformatics specialists, geneticists, or data analysts working with genomic data. These professionals analyze and interpret genetic variants—differences in DNA sequences—to understand their impact on health, disease, and traits. Responsibilities may include utilizing specialized software, conducting research, and collaborating with other scientists or healthcare professionals to translate genetic findings into actionable insights. Variant jobs are commonly found in research institutions, healthcare organizations, and biotechnology companies.

What are some typical challenges faced by professionals working in genetic variant interpretation roles?

Professionals in genetic variant interpretation often encounter challenges such as managing large volumes of complex genomic data, staying current with rapidly evolving scientific literature, and ensuring accurate classification of novel variants. Collaboration with clinicians, bioinformaticians, and laboratory staff is essential to resolve ambiguous findings and provide actionable results. Additionally, balancing the need for thoroughness with timely reporting is a common challenge, especially in clinical or diagnostic settings.
What are popular job titles related to Variant jobs in California? For Variant jobs in California, the most frequently searched job titles are:
What job categories do people searching Variant jobs in California look for? The top searched job categories for Variant jobs in California are:
Variant jobs near you
Clinical Genomics Variant Scientist

Clinical Genomics Variant Scientist

UCLA Health

Los Angeles, CA

$105K - $234K/yr

Full-time

Posted 11 days ago

UCLA Health rating

8.7

Company rating: 8.7 out of 10

Based on 134 frontline employees who took The Breakroom Quiz

6th of 870 rated healthcare providers

Job description

Description

The Molecular Diagnostics Laboratory is seeking an experienced Variant Scientist to join our clinical team. In this critical role, you will curate and interpret germline and somatic variants and prepare high-quality clinical reports derived from exome and targeted cancer sequencing assays. You will contribute to variant classification, test development efforts, and clinical research projects that advance precision medicine for patients across UCLA Health and beyond. Primary duties include:

• Review and assess patient clinical notes and sequencing data from high-complexity molecular assays, including Clinical Exome Sequencing, Solid Tumor Sequencing Panels, and Hematologic Malignancy Sequencing Panels.

• Perform variant curation and interpretation using established guidelines and evidence-based resources.

• Draft and refine clinical reports, ensuring accuracy, clarity, and clinical relevance.

• Develop and update SOPs for variant curation, interpretation, and reclassification workflows

• Participate in submitting curated variants to public databases (e.g. ClinVar) and contribute to quality improvement and test development initiatives.

• Collaborate with clinicians, genetic counselors, and laboratory staff to support accurate and timely reporting.

• Contribute to clinical research projects and assist in implementing new molecular diagnostic assays.

Salary Range: $105,700.00 - $234,500.00/year 

Qualifications
• At least two years’ experience in germline variant curation is required. Somatic variant curation experience is a plus.
• Strong working knowledge of laboratory genetics and genomics, including target capture, amplification, and massively parallel sequencing.
• Familiarity with widely used genomic tools such as IGV and UCSC/COSMIC genome browsers
• Ability to establish effective working relationships with clinicians, genetic counselors, and other team members.
• Programming or bioinformatics experience (e.g. R, SAS, Perl, Python, regex, database design) – preferred.
• PhD in human genetics, molecular genetics, cancer biology, or a related discipline – preferred. Master’s degree in molecular biology, genetics, or a closely related field may be considered with relevant experience.

What UCLA Health employees say

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About UCLA Health

Sourced by ZipRecruiter

UCLA Health, operating within the healthcare industry, is significantly recognized for its commitment to improving the health and wellbeing of people through the integration of patient care, research, and education. Located in Los Angeles, California, UCLA Health was founded and associated with the University of California, Los Angeles (UCLA) in 1955, entrenching its roots in quality healthcare service provision. Through a broad range of medical services, UCLA Health significantly stands as a cornerstone for comprehensive outpatient, inpatient, and emergency care services, specialized treatments, and wellness checks. Notable for pioneering an integrated, comprehensive medical approach, UCLA Health is consistently ranked among the top health systems in the US and world.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Los Angeles, CA, US

Year founded

1955

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