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Variant Jobs in California (NOW HIRING)

Scientific Sales, Oncology

San Diego, CA · On-site

$80K - $120K/yr

This role will support our genomic variant products and services business unit-directly targeting cancer applications for market growth. Candidates with prior sales experiences selling NGS-based ...

SAP SD Lead Architect

Fremont, CA · On-site

$85 - $90/hr

Deep expertise in Order-to-Cash (O2C) lifecycle with Variant configuration. * Pricing and billing processes. * Delivery and logistics integration. * Strong understanding of integration with FI (R2R ...

Associate Laboratory Director

San Carlos, CA

$128K - $167K/yr

Oversee the review of genetic and CNV variant data: interpret NGS and microarray results in the context of medical literature, online variant databases and other references along with relevant ...

Expert knowledge of medical genetics, laboratory genetics and genomics, molecular cytogenetics, structural variant interpretation, ISCN nomenclature, and clinically relevant genotype-phenotype ...

New

Associate Laboratory Director

San Carlos, CA · On-site

$128K - $167K/yr

Oversee the review of genetic and CNV variant data: interpret NGS and microarray results in the context of medical literature, online variant databases and other references along with relevant ...

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Showing results 1-20

Variant information

See California salary details

$10

$21

$31

How much do variant jobs pay per hour?

As of Aug 5, 2026, the average hourly pay for variant in California is $21.01, according to ZipRecruiter salary data. Most workers in this role earn between $16.59 and $23.03 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a variant analyst?

To thrive as a Variant Analyst, you need a solid understanding of genetics, molecular biology, and bioinformatics, often supported by a relevant degree in life sciences or computational biology. Familiarity with genomic analysis tools (like GATK, ANNOVAR), databases (ClinVar, gnomAD), and scripting languages such as Python or R is typically required. Strong attention to detail, analytical thinking, and effective communication help distinguish top performers in this role. These competencies are crucial for accurately interpreting genetic variants, ensuring reliable results, and collaborating with multidisciplinary teams in clinical or research settings.

What is a variant?

Variant jobs typically refer to roles within companies that focus on genetic variant analysis, such as bioinformatics specialists, geneticists, or data analysts working with genomic data. These professionals analyze and interpret genetic variants—differences in DNA sequences—to understand their impact on health, disease, and traits. Responsibilities may include utilizing specialized software, conducting research, and collaborating with other scientists or healthcare professionals to translate genetic findings into actionable insights. Variant jobs are commonly found in research institutions, healthcare organizations, and biotechnology companies.

What are some typical challenges faced by professionals working in genetic variant interpretation roles?

Professionals in genetic variant interpretation often encounter challenges such as managing large volumes of complex genomic data, staying current with rapidly evolving scientific literature, and ensuring accurate classification of novel variants. Collaboration with clinicians, bioinformaticians, and laboratory staff is essential to resolve ambiguous findings and provide actionable results. Additionally, balancing the need for thoroughness with timely reporting is a common challenge, especially in clinical or diagnostic settings.
What job categories do people searching Variant jobs in California look for? The top searched job categories for Variant jobs in California are:
Infographic showing various Variant job openings in California as of July 2026, with employment types broken down into 90% Full Time, 6% Part Time, and 4% Contract. Highlights an 91% Physical, 4% Hybrid, and 5% Remote job distribution, with an average salary of $43,702 per year, or $21 per hour.

Bioinformatics Engineer - Variant

LatchBio

San Francisco, CA • On-site, Remote

$120K - $180K/yr

Full-time

Re-posted 4 days ago


Job description

Bioinformatics Engineer - Variant
As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high-performance agents for biological data analysis, empowering over 5,000 scientists across 150+ R&D labs to handle data from instrument-to-insights.
We're seeking a Bioinformatics Engineerto join our Variant team working at the frontier of what artificial intelligence can achieve in biology.
About the Role
You'll design, build, and evaluate LLM benchmarks for genomic analysis - spanning read alignment, assembly, variant calling, GWAS, causal inference, and multiomics integration. Your benchmarks and evaluations will set the bar for how well AI agents can serve as analysis partners for scientists working with human genetics data.
You'll own the full evaluation pipeline: choosing datasets, defining failure modes, writing grading scripts, and shipping evaluations that measure real capability. Your work directly impacts how LLMs reason through genomic problems.
Requirements
  • Master's or PhD in bioinformatics, genetics, biology, statistics, or related field
  • 3-5 years of hands-on research experience analyzing genomics datasets (especially human data), demonstrated through publications or industry work
  • Deep expertise in at least one of: population genetics, statistical genetics, clinical genomics
  • Fluency with genotyping workflows: variant calling, fine-mapping, Mendelian randomization

Nice-to-Have
  • Experience building open-source bioinformatics software
  • Familiarity with LLM-powered tools, prompting, or evaluation frameworks
  • Background in cross-trait analysis or multiomics integration

Culture @ Latch
How we work. Genuinely flexible schedules - we just ask that you communicate when you're coming in later than usual. We care most about hard work and output. We're respectfully opinionated, it will always be us against problems, not each other. Optimize for each other's time and bring solutions, not just problems. You'll join a bench suited to your expertise, but we value cross-domain learning and interoperability across teams.
The office & perks. Waterfront office near Oracle Park, 2x free daily meals, unlimited snacks, company outings most months, and team offsites. Plus a vibrant community: cycling, soccer, figure skating, boxing, run clubs, reading clubs, martial arts, music, game nights.
Compensation & Logistics
  • 1099 (or W8-BEN) contract, 40 hrs/week, no end date
  • Fully performance-based pay: $120K-$180K, uncapped upside. 2x quota = 2x pay.
  • 2-4 week paid ramp - full OTE from day one
  • Remote (globally), hybrid, or onsite in SF (onsite preferred)
  • Work authorization: OPT visa holders only (not STEM Extension)
  • Onsite perks: 2x free meals/day, waterfront office (China Basin), monthly parking (based on availability)
  • Candidates with all of the above qualifications + proven management skills will be eligible for more senior positions

Interview Process
Timeline: We move fast: 8-12 days from submission to offer.
  1. Intro Screen - Techcnial Recruiter
  2. Take-Home Project - HackerRank
  3. Technical Interview - Member of Technical Staff
  4. Culture Interview - C-Suite (If applicable)
  5. Offer

LatchBio logo

About LatchBio

Sourced by ZipRecruiter

Industry

Biotechnology research and development

Company size

11 - 50 Employees

Headquarters location

San Francisco, CA, US

Year founded

2021

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