ZipRecruiter

Log In

1

Upstream Process Development Jobs in Philadelphia, PA

Wood Plc

Senior Process Engineer

Philadelphia, PA · On-site +1

$104K - $135K/yr

A key contributor on process engineering design teams (upstream, downstream, utilities, fill ... Participating in project planning, cost development, and project scheduling * Maintaining effective ...

Globusmedical

Analytical Scientist

Audubon, PA

Collaborate cross-functionally with upstream/downstream process development, formulation, and quality teams to support CMC development. * Analyze and interpret complex data, provide scientific ...

Globus Medical

Analytical Scientist

Audubon, PA · On-site

Collaborate cross-functionally with upstream/downstream process development, formulation, and quality teams to support CMC development. * Analyze and interpret complex data, provide scientific ...

Drayer Physical Therapy

Physical Therapist

Middletown, PA · On-site

$78K - $95K/yr

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

previous page

Showing results 41-60

All JobsUpstream Process Development JobsUpstream Process Development Jobs in Philadelphia, PA

Upstream Process Development information

See Philadelphia, PA salary details

$19

$26

$37

How much do upstream process development jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for upstream process development in Philadelphia, PA is $26.76, according to ZipRecruiter salary data. Most workers in this role earn between $23.75 and $28.12 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in upstream process development?

Success in Upstream Process Development requires a strong background in biology, biochemistry, or chemical engineering, often with an advanced degree and experience in cell culture or fermentation techniques. Familiarity with bioreactors, process control systems, and analytical instrumentation, as well as knowledge of cGMP regulations, is essential. Critical thinking, problem-solving, and effective communication are important soft skills for optimizing processes and collaborating across multidisciplinary teams. These competencies ensure efficient development of scalable production processes, maintaining product quality and regulatory compliance.

What are some common challenges faced in upstream process development and how do teams typically address them?

One of the main challenges in upstream process development is optimizing cell culture conditions to consistently achieve high yields and product quality. Teams often encounter variability in biological systems and must troubleshoot issues such as contamination, scale-up inconsistencies, or nutrient limitations. Collaboration with analytical, downstream, and quality teams is essential to identify root causes and implement solutions. Regular data review meetings, cross-functional problem-solving, and continuous process improvement are standard practices to ensure robust upstream processes.

What is the difference between Upstream Process Development vs Downstream Process Development?

AspectUpstream Process DevelopmentDownstream Process Development
FocusDevelopment of cell culture, fermentation, and bioreactor processesPurification, filtration, and formulation of bioproducts
Skills & CredentialsBioprocess engineering, molecular biology, biochemistryBioprocessing, chromatography, analytical chemistry
Work EnvironmentLaboratories, bioreactors, pilot plantsPurification facilities, labs, quality control
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical manufacturing

Upstream Process Development focuses on creating and optimizing cell culture and fermentation processes to produce bioproducts. In contrast, Downstream Process Development involves purifying and finishing these products. Both roles are essential in biopharmaceutical manufacturing and require similar scientific backgrounds, but they specialize in different stages of bioprocessing.

What are common upstream process development jobs?

Common upstream process development jobs include roles such as upstream process scientist, process engineer, and bioprocess development specialist. These positions focus on optimizing cell culture, fermentation, and bioreactor processes to improve product yield and quality, often requiring knowledge of bioreactor operation, cell biology, and process scale-up. Skills in laboratory techniques, process modeling, and regulatory compliance are also important in these roles.

What is an upstream process development job?

An upstream process development job involves designing, optimizing, and scaling the early stages of biopharmaceutical production, such as cell culture and fermentation processes. Professionals in this role typically work with bioreactors, laboratory equipment, and process analytical tools to improve yield and quality of biological products. Strong knowledge of microbiology, biochemistry, and process engineering is essential, along with adherence to regulatory standards.

What are popular job titles related to Upstream Process Development jobs in Philadelphia, PA?

For Upstream Process Development jobs in Philadelphia, PA, the most frequently searched job titles are:

What job categories do people searching Upstream Process Development jobs in Philadelphia, PA look for?

The top searched job categories for Upstream Process Development jobs in Philadelphia, PA are:

Upstream Process Development jobs near you
Infographic showing various Upstream Process Development job openings in Philadelphia, PA as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 79% Full Time, 17% Part Time, and 2% Contract. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution, with an average salary of $55,652 per year, or $26.8 per hour.

Scientific Process Operator

Malvern, PA • On-site

Artech Information System LLC
Recruiting and Staffing Services • 10K+ employees
Learn more about Artech Information System LLCexternal

Contractor

Re-posted 16 days ago

Job description

Company Description

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.

Job Description

This position is responsible for performing manufacturing procedures and the execution of scheduled tasks within a CGMP environment in the Upstream group. This position is responsible for quality and maintaining the highest standards in compliance within company policies, procedures and all applicable regulations. 

ESSENTIAL FUNCTIONS: 

Executes manufacturing processes according to Technical Operations and Operational Services standard operating procedures 

Verifies and enters production parameters per SOP and Batch Record on trained procedures 

Retrieves and analyze trend charts and process data on trained procedures 

Accurately completes documentation in SOP's, logbooks and other GMP documents 

Demonstrate training progression through assigned curriculum 

Accountable for adherence to compliance policies and regulations 

Wear the appropriate PPE when working in manufacturing and other hazardous working environments 

Takes necessary action to eliminate safety hazards and communicate to others any observed unsafe behaviors 


ADDITIONAL RESPONSIBILITIES/DUTIES: 

Carries out duties in compliance with all state and federal regulations and guidelines including FDA, EPA and OSHA. 

Adheres to the Safety Code of Conduct and attend all required EHS training 

Support the ongoing production schedule by: 

Report to work on-time and according to the shift schedule 

Be available for other duties as assigned 

Attend departmental and other scheduled meetings 

Good interpersonal and communication skills 

Demonstrates positive team-oriented attitude in the daily execution of procedures 

Promote and work within a team environment 

Continue professional development through learning new skills, procedures, processes 

and seminars 



Qualifications

College degree or HS Diploma with +5 years biopharmaceutical industry experience 

Experience must be Biotech/Pharmaceutical industry or relevant experience working with Standard Operating Procedures (SOP's) where formal documentation is required 

Previous experience with Manufacturing Execution System (MES) would be an advantage 

Mechanical aptitude for assembling and disassembling process equipment would be an advantage 

Process flow aptitude to recognize and understand process pathways 

Knowledge of routine and non-routine testing and sampling methods, techniques and related equipment would be an advantage 


Additional Information

Regards,

Sneha Shrivastava

9739673348



Artech logo

About Artech

Sourced by ZipRecruiter

Artech is a leading IT staffing and consulting company based in Morristown, NJ, US. Since its foundation in 1992, Artech has mastered in complementing human expertise with technology and business acumen to produce world-class staffing solutions. The company caters to diverse industry sectors, including financial services, healthcare, telecommunication, energy and utilities, supply chain, and retail. It provides IT consulting, project management, professional and staff augmentation, and managed staffing services. Artech's mission is to provide exceptional IT staffing services to its clients by comprehending their business needs and then crafting a customized staffing strategy. Its notable achievement includes being recognized as one of the largest IT staffing companies in the U.S, according to Staffing Industry Analysts (SIA).

Industry

Recruiting and staffing services

Company size

10,000+ Employees

Headquarters location

Morristown, NJ, US

Year founded

1992

View All Artech Jobs

Apply