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Upstream Process Development Jobs in Philadelphia, PA

Supply Chain Intern

Pennsauken, NJ · On-site

$17.75 - $24/hr

... development. Discover why Cooper University Health Care is the employer of choice in South Jersey ... The Strategic Sourcing Division is tasked with upstream sourcing assessments of market activity ...

Supply Chain Intern

Pennsauken, NJ · On-site

$17.75 - $24/hr

... development. Discover why Cooper University Health Care is the employer of choice in South Jersey ... The Strategic Sourcing Division is tasked with upstream sourcing assessments of market activity ...

Settlement Processing: The Analyst will learn and utilize in-house developed software tools and ... and upstream systems for accuracy and completeness. The Analyst will be expected to resolve data ...

Validation Engineer

King Of Prussia, PA · On-site

$72K - $80K/yr

... processes, and elite expertise developed over 30 years. Our Purpose We exist to be the trusted ... HVAC) - Upstream/downstream processing - Purification, recovery - Building automation ...

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Upstream Process Development information

See Philadelphia, PA salary details

$19

$26

$37

How much do upstream process development jobs pay per hour?

As of Jun 15, 2026, the average hourly pay for upstream process development in Philadelphia, PA is $26.76, according to ZipRecruiter salary data. Most workers in this role earn between $23.75 and $28.12 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in Upstream Process Development, and why are they important?

Success in Upstream Process Development requires a strong background in biology, biochemistry, or chemical engineering, often with an advanced degree and experience in cell culture or fermentation techniques. Familiarity with bioreactors, process control systems, and analytical instrumentation, as well as knowledge of cGMP regulations, is essential. Critical thinking, problem-solving, and effective communication are important soft skills for optimizing processes and collaborating across multidisciplinary teams. These competencies ensure efficient development of scalable production processes, maintaining product quality and regulatory compliance.

What is the difference between Upstream Process Development vs Downstream Process Development?

AspectUpstream Process DevelopmentDownstream Process Development
FocusDevelopment of cell culture, fermentation, and bioreactor processesPurification, filtration, and formulation of bioproducts
Skills & CredentialsBioprocess engineering, molecular biology, biochemistryBioprocessing, chromatography, analytical chemistry
Work EnvironmentLaboratories, bioreactors, pilot plantsPurification facilities, labs, quality control
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical manufacturing

Upstream Process Development focuses on creating and optimizing cell culture and fermentation processes to produce bioproducts. In contrast, Downstream Process Development involves purifying and finishing these products. Both roles are essential in biopharmaceutical manufacturing and require similar scientific backgrounds, but they specialize in different stages of bioprocessing.

What is upstream process development?

Upstream process development refers to the optimization and scaling of biological production processes that occur before product harvesting. This primarily involves the cultivation of cells or microorganisms to produce a desired product, such as a protein or antibody, in bioreactors. Scientists in this field work on improving cell lines, culture media, and fermentation conditions to maximize yield and quality. Upstream process development is a critical early phase in biomanufacturing, laying the foundation for downstream processing and overall production efficiency.

What are some common challenges faced in upstream process development and how do teams typically address them?

One of the main challenges in upstream process development is optimizing cell culture conditions to consistently achieve high yields and product quality. Teams often encounter variability in biological systems and must troubleshoot issues such as contamination, scale-up inconsistencies, or nutrient limitations. Collaboration with analytical, downstream, and quality teams is essential to identify root causes and implement solutions. Regular data review meetings, cross-functional problem-solving, and continuous process improvement are standard practices to ensure robust upstream processes.
What are popular job titles related to Upstream Process Development jobs in Philadelphia, PA? For Upstream Process Development jobs in Philadelphia, PA, the most frequently searched job titles are:
Senior Manager, P2P Support Desk

Senior Manager, P2P Support Desk

Comcast

Philadelphia, PA

Full-time

Posted 20 days ago


Job description

Comcast brings together the best in media and technology. We drive innovation to create the world's best entertainment and online experiences. As a Fortune 50 leader, we set the pace in a variety of innovative and fascinating businesses and create career opportunities across a wide range of locations and disciplines. We are at the forefront of change and move at an amazing pace, thanks to our remarkable people, who bring cutting-edge products and services to life for millions of customers every day. If you share in our passion for teamwork, our vision to revolutionize industries and our goal to lead the future in media and technology, we want you to fast-forward your career at Comcast.

Job Summary

The Senior Manager of the Procure-to-Pay (P2P) Service Desk leads a centralized support team responsible for delivering timely and accurate assistance to employees, vendors, and business stakeholders across purchasing, vendor setup, invoice workflows, payment status, and expense-related inquiries. This role emphasizes customer service, issue resolution, knowledge management, trend analysis, and continuous improvement. The Senior Manager drives a high-quality support experience and partners cross-functionally to eliminate root-cause issues and increase adoption of policies, tools, and digital solutions.

Job Description

Core Responsibilities

Service Desk Leadership

  • Leads daily operations of the P2P Service Desk, ensuring inquiries are resolved accurately, quickly, and with a customer-centric mindset.
  • Ensures service-level agreements (SLAs), response time targets, backlog thresholds, and customer satisfaction goals are consistently met.
  • Manages ticket intake, triage, prioritization, and escalation paths.
  • Develops analytics and reporting to monitor performance, identify trends, and recommend improvements.

Policy, Guidance & User Support

  • Provides expert-level guidance on purchasing, vendor management, invoice workflow, and expense-related policies.
  • Ensures team members deliver consistent support aligned with documented policies and procedures.
  • Identifies trends in recurring questions and partners with leadership to update FAQs, training materials, and self-service resources.

Training & Staff Development

  • Ensures team members are fully trained on systems, policies, service protocols, and issue-resolution standards.
  • Provides coaching, performance feedback, and development planning.
  • Creates a supportive, high-performing environment that prioritizes service excellence and continuous improvement.

Process Improvement & Root Cause Resolution

  • Monitors common support issues to identify root causes and works with cross-functional teams such as Accounting, Procurement, Technology, and Operations to reduce or eliminate repeat inquiries.
  • Enhances self-service tools, knowledge articles, user documentation, and communication channels.
  • Leveraging data and insights to recommend process enhancements, automation opportunities, and policy updates.
  • Champions digital solutions and automation that improve the ease and efficiency of the support experience.

Business Partnership & Communication

  • Acts as the primary escalation point for complex vendor and employee support issues.
  • Provides insights, trends, and recommendations to leadership to improve upstream processes and overall customer experience.
  • Influences cross-functional decision-making by communicating service challenges, user pain points, and emerging themes.

Other Responsibilities

  • Exercises independent judgment and discretion in resolving significant support matters.
  • Maintains high standards of reliability, punctuality, and professionalism; supports flexible hours as needed.
  • Performs other duties and responsibilities as assigned.

Preferences

Education & Experience

  • Bachelor's degree in Business, Accounting, Finance, Supply Chain, or related field; or equivalent experience.
  • 5-7 years of experience in Accounts Payable, Procure-to-Pay, purchasing support, shared services, or related financial operations.
  • 3+ years of experience supervising, leading, or managing a customer support, service desk, or financial operations team.support, service desk, or financial operations team.
  • Experience working with purchasing systems, invoice workflows, vendor management tools, and expense platforms.
  • Strong background in support operations, ticketing systems, and customer service process management.service process management.

Knowledge & Skills

  • Ability to interpret and explain Accounts Payable and purchasing policies to employees and vendors.
  • Strong analytical and problem solving skills with the ability to identify trends, root causes, and recommended improvements.solving skills with the ability to identify trends, root causes, and recommended improvements.
  • Excellent communication skills-verbal, written, and interpersonal-with the ability to interact effectively with employees at all levels and external suppliers.
  • Demonstrated ability to manage multiple priorities in a fast paced environment while maintaining high accuracy and attention to detail.paced environment while maintaining high accuracy and attention to detail.
  • Familiarity with ERP systems (Oracle, SAP, Workday, or similar) preferred.
  • Ability to coach, motivate, and develop team members.

Leadership & Behavioral Competencies

  • Strong customer service orientation and ability to model and reinforce a service focused culture.service orientation and ability to model and reinforce a servicefocused culture.
  • Demonstrated ability to exercise independent judgment and discretion in matters of significance.
  • Proven ability to build strong working relationships across departments such as Finance, Sourcing, IT, and Operations.
  • Ability to manage confidential information with professionalism and integrity.
  • Comfortable facilitating feedback loops, communicating trends, and leading continuous improvement activities.improvement activities.

Employees at all levels are expected to:

  • Understand our Operating Principles; make them the guidelines for how you do your job.
  • Own the customer experience - think and act in ways that put our customers first, give them seamless digital options at every touchpoint, and make them promoters of our products and services.
  • Know your stuff - be enthusiastic learners, users and advocates of our game-changing technology, products and services, especially our digital tools and experiences.
  • Win as a team - make big things happen by working together and being open to new ideas.
  • Be an active part of the Net Promoter System - a way of working that brings more employee and customer feedback into the company - by joining huddles, making call backs and helping us elevate opportunities to do better for our customers.
  • Drive results and growth.
  • Support a culture of inclusion in how you work and lead.
  • Do what's right for each other, our customers, investors and our communities.

Disclaimer:

  • This information has been designed to indicate the general nature and level of work performed by employees in this role. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications.

Skills

Accounts Payable (AP), Procure-to-Pay, Service Desk Management

We believe that benefits should connect you to the support you need when it matters most, and should help you care for those who matter most. That's why we provide an array of options, expert guidance and always-on tools that are personalized to meet the needs of your reality-to help support you physically, financially and emotionally through the big milestones and in your everyday life.


Please visit the benefits summary on our careers site for more details.

Education

Bachelor's DegreeWhile possessing the stated degree is preferred, Comcast also may consider applicants who hold some combination of coursework and experience, or who have extensive related professional experience.

Certifications (if applicable)

Relevant Work Experience

7-10 YearsComcast is an equal opportunity workplace. We will consider all qualified applicants for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability, veteran status, genetic information, or any other basis protected by applicable law.