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Upstream Process Development Scientist Jobs in Maryland

US Tech Solutions

Associate Scientist

Gaithersburg, MD · On-site

This position is focused on upstream cell culture and fermentation processes supporting scalability ... stage development to DSC as well as assisting in the production of various tox and development ...

CybSafe

Process Engineer - Graphite

Baltimore, MD · On-site

$110 - $160/hr

Work side-by-side with R&D scientists/engineers to understand the chemistry, reaction kinetics, and unit operations underlying the novel process including designing and running experiments and ...

ETCH, Inc

Process Engineer - Graphite

Baltimore, MD · On-site

Work side-by-side with R&D scientists/engineers to understand the chemistry, reaction kinetics, and unit operations underlying the novel process including designing and running experiments and ...

ETCH, Inc

Process Engineer - Graphite

Baltimore, MD · On-site

Work side-by-side with R&D scientists/engineers to understand the chemistry, reaction kinetics, and unit operations underlying the novel process including designing and running experiments and ...

Peraton

Development Support Process Engineer

Linthicum, MD · On-site

$146K - $234K/yr

As a Development Support Process Engineer, you will support a customer Program Management Office ... Bachelor's degree in Computer Science, Information Systems, Engineering, Business, or Education ...

Peraton

Development Support Process Engineer

Linthicum, MD · On-site

$146K - $234K/yr

As a Development Support Process Engineer, you will support a customer Program Management Office ... Bachelor's degree in Computer Science, Information Systems, Engineering, Business, or Education ...

Peraton

Development Support Process Engineer

Linthicum, MD · On-site

$146K - $234K/yr

As a Development Support Process Engineer, you will support a customer Program Management Office ... Bachelor's degree in Computer Science, Information Systems, Engineering, Business, or Education ...

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Upstream Process Development Scientist information

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$20

$37

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How much do upstream process development scientist jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for upstream process development scientist in Maryland is $37.52, according to ZipRecruiter salary data. Most workers in this role earn between $27.55 and $44.81 per hour, depending on experience, location, and employer.

What does an upstream process development scientist do?

An Upstream Process Development Scientist is responsible for designing, optimizing, and scaling up processes for the production of biological products such as proteins, vaccines, or antibodies. They primarily focus on cell culture, fermentation, and bioreactor operations to maximize yield and product quality. These scientists work closely with research and manufacturing teams to develop efficient and reproducible processes that can be transferred to large-scale production. Their work is essential in the biotechnology and pharmaceutical industries for the development of new therapeutics.

What are some typical challenges faced by an upstream process development scientist, and how are they addressed in the workplace?

Upstream Process Development Scientists often encounter challenges such as optimizing cell culture conditions for maximum yield, scaling up processes from bench to pilot or production scale, and troubleshooting variability in biological systems. These challenges are typically addressed through rigorous experimental design, close collaboration with cross-functional teams like analytical development and quality assurance, and leveraging data-driven approaches to problem-solving. Regular team meetings and access to advanced instrumentation also provide support, ensuring that scientists can quickly adapt to evolving project needs and industry standards.

What are the key skills and qualifications needed to thrive as an upstream process development scientist, and why are they important?

To thrive as an Upstream Process Development Scientist, you need a strong background in bioprocess engineering, cell culture, and molecular biology, typically supported by a degree in life sciences or biochemical engineering. Familiarity with bioreactor systems, analytical instrumentation, and data analysis software, as well as experience with cGMP and regulatory guidelines, is essential. Strong problem-solving abilities, teamwork, and effective communication help drive innovation and collaboration in the lab. These skills are crucial for optimizing cell culture processes, ensuring product quality, and meeting timelines in biopharmaceutical development.

What is the difference between Upstream Process Development Scientist vs Downstream Process Development Scientist?

AspectUpstream Process Development ScientistDownstream Process Development Scientist
Focus AreaBioreactor cultivation, cell culture optimization, media developmentPurification, filtration, chromatography, product recovery
Skills & CertificationsCell biology, bioprocessing, GMP regulationsProtein chemistry, purification techniques, GMP compliance
Work EnvironmentLaboratories, bioreactors, pilot plantsLaboratories, purification facilities, pilot plants
Industry UsageBiopharmaceuticals, biotech companies, contract manufacturingBiopharmaceuticals, biotech companies, contract manufacturing

Both roles are essential in bioprocessing, with upstream scientists focusing on cell growth and media optimization, while downstream scientists handle product purification. They often collaborate closely within biopharmaceutical manufacturing to ensure efficient production and high-quality biologics.

What are popular job titles related to Upstream Process Development Scientist jobs in Maryland?

For Upstream Process Development Scientist jobs in Maryland, the most frequently searched job titles are:

What job categories do people searching Upstream Process Development Scientist jobs in Maryland look for?

The top searched job categories for Upstream Process Development Scientist jobs in Maryland are:

What cities in Maryland are hiring for Upstream Process Development Scientist jobs?

Cities in Maryland with the most Upstream Process Development Scientist job openings:

Upstream Process Development Scientist jobs near you
Infographic showing various Upstream Process Development Scientist job openings in Maryland as of August 2026, with employment types broken down into 1% As Needed, 84% Full Time, 13% Part Time, and 2% Contract. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution, with an average salary of $78,051 per year, or $37.5 per hour.

Associate Scientist

US Tech Solutions

Gaithersburg, MD • On-site

Contractor

Re-posted 19 days ago

Job description

Company Description

US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website www.ustechsolutions.com.

We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well.

Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset.

Job Description

BioProcess Engineering (BPE) department is responsible for scale up, tech transfer, and facility fit of clinical and commercial processes to manufacturing. BPE is also responsible for producing development drug substance material and data from pilot facilities. Members of Development Scale-up Center (DSC), within BPE, produce materials up to 500L scale for toxicology and process development studies, to confirm process performance and to troubleshoot issues in GMP facility, and work with cross functional team on technology evaluations.   

This position is focused on upstream cell culture and fermentation processes supporting scalability and production of therapeutic proteins in DSC. Position is a hands-on laboratory and production-based role. Responsibilities include but are not limited to media preparations, routine sub-culturing of cells and fermentations. The candidate will assist in adaptation of transferred information for scale-up processes from late stage development to DSC as well as assisting in the production of various tox and development materials, troubleshooting and resolving technical issues with the production processes and/or equipment, identifying root causes for deviations, implementing corrective/preventative actions, assisting in implementing new technologies, and trending/analyzing data. 

The candidate will assist in compiling data and expected to summarize and assist in interpreting results. The candidate will also maintain production and laboratory equipment.  


Qualifications

Education: 

Bachelor of Science (BS) or Master of Science (MS) in scientific, engineering or related field.  

Experience:

For the RA, we require a BS with 2 - 5 years or a MS with 0 - 2 years of relevant experience.  

For the AS, we require a BS with a minimum of 5 years or MS with a minimum of 2 years of relevant experience.


Additional Information

Special Skills/ Abilities

Hands on proficiency in cell culture and/or fermentation and good aseptic techniques. Bioreactor/fermenter operation experience is preferred. 

Good documentation, writing and communication skills in a team based setting are essential.  


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About US Tech Solutions

Sourced by ZipRecruiter

US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions.

Industry

It services

Company size

1,001 - 5,000 Employees

Headquarters location

Jersey City, NJ, US

Year founded

2000

Social media

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