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Toxicokinetic Jobs (NOW HIRING)

Wave Life Sciences

Senior Scientist I, DMPK

Lexington, MA · On-site

$157K - $213K/yr

The successful candidate will play a key role in independently designing, executing, and interpreting pharmacokinetic (PK), toxicokinetic (TK), plasma protein binding and in vitro drug-drug ...

Amgen

Scientist, Bioanalytical Sciences

$36 - $45.25/hr

Individuals in this role will provide scientific and technical oversight of bioanalytical activities (including pharmacokinetic [PK] and toxicokinetic [TK] analyses) performed by external contract ...

Wave Life Sciences

Senior Scientist I, DMPK

Lexington, MA · On-site

$157 - $213/hr

The successful candidate will play a key role in independently designing, executing, and interpreting pharmacokinetic (PK), toxicokinetic (TK), plasma protein binding and in vitro drug‑drug ...

State of Washington

Toxicologist 2

Olympia, WA · On-site +1

$80K - $108K/yr

... toxicokinetic and toxicodynamic characteristics of toxic agents in hazardous waste. Represent the Program on task groups within the department and in coordination with external agencies and other ...

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Toxicokinetic information

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How much do toxicokinetic jobs pay per hour?

As of Sep 2, 2026, the average hourly pay for toxicokinetic in the United States is $76.10, according to ZipRecruiter salary data. Most workers in this role earn between $15.38 and $192.31 per hour, depending on experience, location, and employer.

What is toxicokinetics?

Toxicokinetics is the study of how a chemical substance enters, moves through, and exits the body, focusing on its absorption, distribution, metabolism, and excretion. Toxicokineticists use this information to predict the concentration of chemicals over time in biological systems and assess potential health risks. This field is crucial in drug development, chemical safety assessment, and regulatory toxicology to ensure substances are safe for humans and the environment.

What are the key skills and qualifications needed to thrive as a toxicokineticist, and why are they important?

To thrive as a Toxicokineticist, you need a solid background in pharmacokinetics, toxicology, and analytical chemistry, typically supported by an advanced degree in a related scientific field. Experience with laboratory instrumentation, data analysis software (such as WinNonlin or Phoenix), and regulatory guidelines is highly valuable. Strong problem-solving skills, attention to detail, and effective communication set outstanding professionals apart in this role. These competencies ensure accurate assessment of chemical behaviors in biological systems, critical for drug safety and regulatory compliance.

What are some common challenges faced by toxicokinetic professionals when interpreting complex pharmacokinetic data?

Toxicokinetic professionals often encounter challenges when interpreting data due to the variability of biological systems, differences in species, and the complex interactions between chemicals and biological matrices. Accurately modeling these interactions requires careful consideration of dose-response relationships, metabolic pathways, and potential data gaps. Collaboration with toxicologists, pharmacologists, and statisticians is essential to ensure robust data interpretation and reliable risk assessments, especially when data are limited or inconsistent.
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What job categories do people searching Toxicokinetic jobs look for?

The top searched job categories for Toxicokinetic jobs are:

Infographic showing various Toxicokinetic job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 85% Physical, and 15% Remote job distribution, with an average salary of $158,293 per year, or $76.1 per hour.

Senior Research Scientist

The Mind Research Network

Albuquerque, NM • On-site

$94K - $120K/yr

Full-time

Posted 12 days ago

Job description

Overview
The Senior Research Scientist is responsible for leading the LC-MS/MS bioanalytical laboratory, ensuring high-quality analytical testing, regulatory compliance, operational excellence, and staff development. This role oversees method development, validation, sample analysis, and laboratory operations supporting preclinical and clinical studies in accordance with GLP, ICH M10, and applicable regulatory guidelines. The manager provides strategic leadership while maintaining efficient laboratory workflows, meeting project time-lines, and ensuring data integrity.
Key Responsibilities
Laboratory Leadership
  • Manage daily operations of the Bioanalytical LC-MS/MS laboratory.
  • Supervise, mentor, and develop scientists, analysts, supervisors, and laboratory staff.
  • Establish and maintain departmental goals, performance metrics, and staffing plans.
  • Foster a culture of scientific excellence, quality, safety, and continuous improvement.
  • Conduct employee performance evaluations and provide coaching and career development.

Scientific Oversight
  • Oversee LC-MS/MS method development, optimization, validation, and transfer.
  • Review bioanalytical method documents, validation reports, study data, and final reports.
  • Ensure bioanalytical methods meet regulatory expectations, LBRI internal SOPs and Sponsor requirements.
  • Provide scientific guidance on troubleshooting complex analytical challenges.
  • Support assay development for small molecules, peptides, metabolites, biomarkers, protein and macro-molecules.
  • Provide on-going training for staff members.

Project Management
  • Coordinate multiple client projects simultaneously.
  • Allocate laboratory resources to meet project time-lines and deliverables.
  • Collaborate with study directors and business development to support Sponsor needs.
  • Monitor project progress, budgets, and laboratory productivity.
  • Communicate project status effectively with internal teams and Sponsors.

Quality & Regulatory Compliance
  • Ensure compliance with:

o ICH M10
o GLP/GCP regulations
o Quality Management System
  • Support internal, Sponsor, and regulatory audits.
  • Review deviations, CAPAs, change controls, and investigations.
  • Maintain complete documentation and data integrity in compliance with ALCOA+ principles.

Instrumentation Management
  • Oversee operation and maintenance of LC-MS/MS instrumentation, including Sciex Triple Quad instruments, Waters and Shimadzu LC units.
  • Ensure instrument validation and qualification, calibration, preventive maintenance, and troubleshooting.
  • Coordinate with vendors for service and technical support.
  • Evaluate and recommend new instrumentation and technologies.

Operational Excellence
  • Monitor laboratory key performance indicators including:

o Turnaround time
o Sample throughput
o Instrument utilization
o Quality metrics
  • Manage laboratory inventory, budgets, and capital equipment planning.
  • Ensure laboratory safety and compliance with environmental health and safety regulations.
  • Represent LBRI at scientific discussion both virtually and in person.
  • Foster a collaborative environment with vendors for new product training and cross-training across internal LBRI teams.

Sponsor Relations
  • Serve as a scientific point of contact for Sponsors.
  • Participate in Sponsor meetings, audits, and technical discussions.
  • Support proposal development and technical feasibility assessments.
  • Build and maintain strong Sponsor relationships through scientific expertise and reliable project execution.

Technical Skills
  • Expert knowledge of:

o LC-MS/MS instrumentation, especially QqQ and HRMS.
o Sample preparation techniques
o Method validation
o Bioanalytical assays
o Pharmacokinetics and Toxicokinetic
  • Strong understanding of bioanalytical regulatory requirements.
  • Familiarity with statistical analysis and data review.

Leadership Competencies
  • Strong people management and mentoring skills.
  • Excellent organizational and project management abilities.
  • Effective written and verbal communication.
  • Strategic thinking and problem-solving.

Qualifications
Requires a Ph.D in Bioanalytical Chemistry as well as ten (10) years of directly related research experience; or an equivalent combination of education, training and/or experience from which comparable knowledge, skills and abilities have been attained. Requires a minimum of 2 years of previous personnel supervision.
Must have experience as a Bioanalytical leader with deep expertise in LC-MS/MS, method development, method validation and sample analysis as well as the ability to summarize data and write reports. The ideal candidate should have previous experience with multiple compound classes that are amenable for quantification by triple quad LC-MS/MS. Must have knowledge of Good Laboratory Practice Guidelines (FDA, OECD, EPA). Preference will be giving to individuals who have experience in a regulated setting (FDA, GLP, ICH, etc.), with ABSciex hardware/software and / or individuals with experience in bioanalytical sample workflows. Preference will be given to candidates with direct relevant experience in GLP bioanalytical chemistry.
Must have demonstrated ability to handle fundamental scientific tasks and have published and/or presented original research in prior roles. Requires research experience in a specific discipline.
Must have superior professional-level written and verbal communication skills; a high degree of professionalism and excellent problem-solving skills. Demonstrated ability in managing a wide variety of complex tasks and projects simultaneously while meeting multiple deadlines is required. Must have the ability to work independently and as a part of a team as well as the ability to maintain confidential information. Requires professional-level computer skills and advanced experience with Excel, as well as the ability to learn department-specific computer systems as needed.
This position will involve work inside the ABSL3 facility which will require vaccinations/immunizations. Ability to obtain and maintain Select Agent clearance is required. A Post-offer physical and background check are required.
This position may require vaccinations/immunizations. A Post-offer physical and background check are required.
Must be a US Citizen or permanent resident in order to gain and maintain access to Kirtland Air Force base (KAFB).
Physical Requirements
Work is performed in an office environment. Will operate standard office equipment and will frequently stand, walk, sit, perform desk-based computer tasks, use a telephone, perform repetitive motions and occasionally lift objects that weigh up to 10 pounds.
The above is intended to describe the general requirements for the position and should not be interpreted as an exhaustive statement of physical requirements. The Institute will provide reasonable accommodation to any employee with a disability who requires an accommodation to perform the essential functions of the position.
Salary
Salary is commensurate with experience.
Lovelace Biomedical is an Equal Opportunity Employer

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