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Tangential Flow Filtration Tff Jobs (NOW HIRING)

Senior Engineer

Bedford, MA · On-site

$116K - $177K/yr

The role is based at our Bedford, MA campus and centers on Tangential Flow Filtration (TFF) technology for next-generation bioprocessing. What you'll do: * Lead technology and product development ...

Knowledge in mRNA downstream methods for Tangential Flow Filtration (TFF) and multiple chromatography techniques such as dT Affinity, IEX, and RP-HPLC. * Experience operating automated chromatography ...

Experience with tangential flow filtration (TFF), including microfiltration and ultrafiltration. * Experience with analytical instrumentation, including plate readers, densitometers, thermocyclers ...

Senior Engineer

Bedford, MA · On-site

$116K - $177K/yr

The role is based at our Bedford, MA campus and centers on Tangential Flow Filtration (TFF) technology for next-generation bioprocessing. What you'll do: * Lead technology and product development ...

Scientist I

San Diego, CA · On-site

$48/hr

Prior experience with Tangential Flow Filtration (TFF), dialysis, and bioconjugation chemistry is highly desirable. * Software & Data: High proficiency in MS Excel is required; hands-on experience ...

Senior Bioprocess Engineer

Burlington, MA · On-site

$113K - $156K/yr

Experience setting up and executing downstream unit operations, including Chromatography, Normal Flow Filtration, and Tangential Flow Filtration (TFF). * Prior experience in analytical methods and ...

Showing results 41-60

Tangential Flow Filtration Tff information

See salary details

$11K

$52.4K

$64K

How much do tangential flow filtration tff jobs pay per year?

As of Sep 12, 2026, the average yearly pay for tangential flow filtration tff in the United States is $52,374.00, according to ZipRecruiter salary data. Most workers in this role earn between $45,000.00 and $62,500.00 per year, depending on experience, location, and employer.

What is tangential flow filtration (TFF)?

Tangential Flow Filtration (TFF) is a filtration technique commonly used in bioprocessing and laboratory applications to separate and purify biomolecules like proteins, viruses, and nucleic acids. Unlike traditional filtration, where the feed passes perpendicular to the filter membrane, in TFF, the solution flows tangentially along the surface of the membrane, reducing clogging and allowing for efficient processing of large volumes. TFF is widely used for concentration, diafiltration, and buffer exchange in research and industrial settings.

What are the key skills and qualifications needed to thrive as a tangential flow filtration (TFF) specialist?

To excel as a Tangential Flow Filtration (TFF) Specialist, you need a background in bioprocessing or chemical engineering, with knowledge of filtration principles and GMP standards. Familiarity with TFF systems, process control software, and relevant certifications such as cGMP or Lean Six Sigma is often required. Strong attention to detail, analytical thinking, and effective communication are crucial soft skills for troubleshooting and collaborating with cross-functional teams. These skills and qualifications ensure efficient, high-quality filtration processes critical to biopharmaceutical manufacturing and regulatory compliance.

What are some common challenges faced in a tangential flow filtration (TFF) role, and how can they be managed?

Professionals working in Tangential Flow Filtration (TFF) often face challenges such as membrane fouling, optimizing process parameters for different biomolecules, and maintaining consistent product quality. Managing these issues typically involves thorough system cleaning, regular monitoring of transmembrane pressure, and adjusting flow rates and buffer conditions. Collaborating closely with upstream and downstream processing teams is essential to ensure seamless integration and troubleshoot issues as they arise. Continuous learning and staying updated with evolving filtration technologies can also help in efficiently overcoming these challenges.

What is the difference between Tangential Flow Filtration Tff vs Microbiologist?

AspectTangential Flow Filtration TffMicrobiologist
Required credentialsTechnical certifications, science or engineering degreeBiology, microbiology degree, certifications often preferred
Work environmentLaboratories, biotech, pharmaceutical manufacturingResearch labs, healthcare, environmental settings
Industry usageBioprocessing, biopharmaceuticals, biotech manufacturingHealthcare, research, environmental monitoring

While Tangential Flow Filtration Tff specialists focus on filtration processes in biotech and pharmaceutical manufacturing, microbiologists study microorganisms and their effects. Both roles require scientific knowledge but differ in daily tasks and industry applications.

What other helpful pages are available for Tangential Flow Filtration Tff?

Other pages related to Tangential Flow Filtration Tff:

Infographic showing various Tangential Flow Filtration Tff job openings in the United States as of September 2026, with employment types broken down into 100% Contract. Highlights an 100% In-person job distribution, with an average salary of $52,374 per year, or $25.2 per hour.

Senior Engineer

Bedford, MA • On-site

$116K - $177K/yr

Full-time

Medical, Retirement, PTO

Re-posted 11 days ago


Job description

Work Location: Bedford, Massachusetts
Shift:
Department: LS-PS-RDFU Ultrafiltration Product Development
Recruiter: Stefanie Fried
This information is for internals only. Please do not share outside of the organization.
Your Role:
MilliporeSigma, a business of Merck KGaA, Darmstadt, Germany, is seeking a Sr. Engineer to join Process Solutions Filtration R&D. The role is based at our Bedford, MA campus and centers on Tangential Flow Filtration (TFF) technology for next-generation bioprocessing.
What you'll do:
  • Lead technology and product development programs around TFF membranes, modules, materials, devices and integrated filtration solutions for therapeutic biopharmaceutical manufacturing.
  • Define technical roadmaps, translate unmet customer needs into scalable TFF concepts, and de-risk through lab and pilot-scale studies.
  • Analyze process bottlenecks, evaluate novel TFF concepts/equipment, and design experiments to optimize flux, selectivity, shear, fouling resistance, and cleaning/sterilization compatibility.
  • Collaborate cross-functionally with Operations, Process Development, Applications, Quality, IP, Regulatory, and commercial teams to ensure robust, scalable, and defensible filtration solutions.
  • Manage project scope, timelines, budgets, and risk (e.g., FMEA); provide post-launch support and iterative improvements.
  • Communicate technical results clearly to both technical and non-technical stakeholders; author technical reports, SOPs, and patent/presentation materials as needed.
  • Occasional domestic/international travel to support programs and customer engagements.

Who You Are
Minimum Qualifications:
  • B.S. in chemical,mechanical or related engineering plus 5-7+ years experience in a related technical area, or MS plus 3-5+ years, or PhD plus 2+ years
  • Track record of new product/process development and validation in filtration/bioprocessing.
  • Demonstrated leadership role in project planning and execution with a diverse project team.
  • Experience in project management, budgeting, risk assessment (e.g. FMEA), validation, and post launch support.
  • Capable to work collaboratively with different functions within and outside of the company.
  • Technical expertise in designing and conducting experiments in laboratory or manufacturing setting with good trouble shooting, problem solving and statistical analysis skills.
  • Strong oral and written communication skills to effectively communicate technical information to different parts of the organization.

Preferred Qualifications:
  • Experience with TFF device design, membrane selection, module integration, and scalable process implementation.
  • IP assessment, patent review/application/publication/external presentation experience.

Role must be based in Bedford, MA
Pay Range for this position: $116,700- $177,700. The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.
The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.