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Tangential Flow Filtration Tff Jobs (NOW HIRING)

Chromatography Tangential Flow Filtration (TFF) Viral Filtration Ultrafiltration/Diafiltration (UF/DF) Monitor critical process parameters (CPPs) and critical quality attributes (CQAs). Perform trend ...

Purify polysaccharides and conjugates using a variety of methods including dialysis, size-exclusion chromatography, and tangential flow filtration (TFF). * Analyze polysaccharides and conjugates with ...

Purification Scientist

Boston, MA Β· On-site

$44 - $46/hr

Perform tangential flow filtration (TFF) for buffer exchange and product concentration * Prepare buffers and manage chromatography columns and consumables * Support experimental design, data ...

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Tangential Flow Filtration Tff information

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$11K

$52.4K

$64K

How much do tangential flow filtration tff jobs pay per year?

As of Sep 12, 2026, the average yearly pay for tangential flow filtration tff in the United States is $52,374.00, according to ZipRecruiter salary data. Most workers in this role earn between $45,000.00 and $62,500.00 per year, depending on experience, location, and employer.

What is tangential flow filtration (TFF)?

Tangential Flow Filtration (TFF) is a filtration technique commonly used in bioprocessing and laboratory applications to separate and purify biomolecules like proteins, viruses, and nucleic acids. Unlike traditional filtration, where the feed passes perpendicular to the filter membrane, in TFF, the solution flows tangentially along the surface of the membrane, reducing clogging and allowing for efficient processing of large volumes. TFF is widely used for concentration, diafiltration, and buffer exchange in research and industrial settings.

What are the key skills and qualifications needed to thrive as a tangential flow filtration (TFF) specialist?

To excel as a Tangential Flow Filtration (TFF) Specialist, you need a background in bioprocessing or chemical engineering, with knowledge of filtration principles and GMP standards. Familiarity with TFF systems, process control software, and relevant certifications such as cGMP or Lean Six Sigma is often required. Strong attention to detail, analytical thinking, and effective communication are crucial soft skills for troubleshooting and collaborating with cross-functional teams. These skills and qualifications ensure efficient, high-quality filtration processes critical to biopharmaceutical manufacturing and regulatory compliance.

What are some common challenges faced in a tangential flow filtration (TFF) role, and how can they be managed?

Professionals working in Tangential Flow Filtration (TFF) often face challenges such as membrane fouling, optimizing process parameters for different biomolecules, and maintaining consistent product quality. Managing these issues typically involves thorough system cleaning, regular monitoring of transmembrane pressure, and adjusting flow rates and buffer conditions. Collaborating closely with upstream and downstream processing teams is essential to ensure seamless integration and troubleshoot issues as they arise. Continuous learning and staying updated with evolving filtration technologies can also help in efficiently overcoming these challenges.

What is the difference between Tangential Flow Filtration Tff vs Microbiologist?

AspectTangential Flow Filtration TffMicrobiologist
Required credentialsTechnical certifications, science or engineering degreeBiology, microbiology degree, certifications often preferred
Work environmentLaboratories, biotech, pharmaceutical manufacturingResearch labs, healthcare, environmental settings
Industry usageBioprocessing, biopharmaceuticals, biotech manufacturingHealthcare, research, environmental monitoring

While Tangential Flow Filtration Tff specialists focus on filtration processes in biotech and pharmaceutical manufacturing, microbiologists study microorganisms and their effects. Both roles require scientific knowledge but differ in daily tasks and industry applications.

What other helpful pages are available for Tangential Flow Filtration Tff?

Other pages related to Tangential Flow Filtration Tff:

Infographic showing various Tangential Flow Filtration Tff job openings in the United States as of September 2026, with employment types broken down into 100% Contract. Highlights an 100% In-person job distribution, with an average salary of $52,374 per year, or $25.2 per hour.

Manufacturing Manager, Bioprocessing

Durham, NC β€’ On-site

Full-time

Posted 25 days ago


Job description

Donaldson is committed to solving the world's most complex filtration challenges. Together, we make cool things. As an established technology and innovation leader, we are continuously evolving to meet the filtration needs of our changing world. Join a culture of collaboration and innovation that matters and a chance to learn, effect change, and make meaningful contributions at work and in communities.
Position Summary:
We are seeking a Manufacturing Manager, Bioprocessing for Isolere Bio, a division of Donaldson and home to the proprietary IsoTagβ„’ technology-a bioprocessing purification solution that delivers better-than-affinity performance without the chromatography column. The company offers a growing portfolio of purification solutions for a wide range of biologics and other viral particles. This high-visibility role will lead and manage establishing production of IsoTag reagents as well as supporting efforts to scale production. Qualified candidates must be able to work an on-site schedule at our Durham, NC office/facility.
Role Responsibilities:
  • Oversee upstream fermentation processes and downstream purification operations including chromatography, tangential flow filtration (TFF), and buffer preparation.
  • Coordinate production activities across manufacturing, quality, operations, and process development functions to meet business objectives
  • Train, develop, supervise manufacturing personnel.
  • Draft, review and approve batch records, deviations, investigations, change controls, and corrective actions.
  • Identify and implement improvements to increase operational efficiency, product quality, and manufacturing capacity.
  • Support technology transfer and process scale-up activities from development to commercial manufacturing by participating in SOP and batch record generation, documentation and training requirements, and other needs for tech transfer.
  • Ensure proper operation, maintenance, calibration, and qualification of manufacturing equipment.
  • Support commissioning and qualification of new manufacturing equipment and process technologies, as well as leading efforts for expansion of capabilities and equipment.
  • Foster a culture of accountability, safety, quality, and continuous improvement.

Minimum Qualifications:
  • Bachelors degree in science, engineering, manufacturing operations, or related field.
  • 5+ years of Bioprocessing experience in biopharmaceutical, industrial biotechnology, or related manufacturing environments.
  • Experience with upstream and/or downstream bioprocessing operations or related bioprocessing manufacturing operations.

Preferred Qualifications:
  • 1+ years of leadership or supervisory experience within a manufacturing setting.
  • Experience with fermentation, chromatography, and/or tangential flow filtration (TFF).
  • Strong understanding of process control, batch manufacturing, and production scheduling.
  • Strong organizational, communication, and leadership skills.
  • Experience in GMP-regulated manufacturing environments.
  • Experience with scale-up, technology transfer, and process validation activities.
  • Knowledge of Lean Manufacturing, Six Sigma, or Operational Excellence methodologies.
  • Experience with contract manufacturing or customer-facing production programs.

Relocation: This position is not eligible for relocation assistance.
Immigration Sponsorship Not Available:
  • Applicants for this position must be currently and legally authorized to work in the United States without the need for current or future sponsorship (e.g., H-1B, J-1, F-1, CPT, OPT, etc.).
  • Donaldson will not offer immigration sponsorship or assume sponsorship of an employment visa for this position.
  • International relocation or remote work arrangements outside of the U.S. will not be considered.

Equal Opportunity Employer, including Disability and Veterans
Employment opportunities for positions in the United States may require use of information which is subject to the export control regulations of the United States. Hiring decisions for such positions are required by law to be made in compliance with these regulations. Applicants for employment opportunities in other countries must be able to meet the comparable export control requirements of that country and of the United States.
Donaldson Company has been made aware that there are several recruiting scams that are targeting job seekers. These scams have attempted to solicit money for job applications and/or collect confidential information, Donaldson will never solicit money during the application or recruiting process. Donaldson only accepts online applications through our Careers | Donaldson Company, Inc. website and any communication from a Donaldson recruiter would be sent using a donaldson.com email address. If you have any questions about the legitimacy of an employment opportunity, please reach out to talentacquisition@donaldson.com to verify that the communication is from Donaldson.
Our policy is to provide equal employment opportunities to all qualified persons without regard to race, gender, color, disability, national origin, age, religion, union affiliation, sexual orientation, veteran status, citizenship, gender identity and/or expression, or other status protected by law.