Summer Internship Computational Biology Jobs in Romeoville, IL

Job Summary:
Argonne National Laboratory is seeking a Software Engineer to serve as a technical lead for the Modular Autonomous Discovery for Science (MADSci) framework. The role involves leading the development and operational support of a Python-based platform that integrates various scientific instruments and AI/ML decision agents for autonomous laboratories.
Responsibilities:
• Lead day-to-day development of the MADSci framework: design and implement new features, triage and resolve bugs, review pull requests, and shepherd releases through the project's CI/CD pipeline.
• Own the architecture of a Python microservices system spanning workflow orchestration, resource and inventory tracking, distributed event logging, experiment management, and device integration.
• Collaborate with experimental scientists and robotics engineers to onboard new instruments, design experiment workflows, and translate scientific goals into robust software abstractions.
• Maintain and grow the contributor community, including external collaborators at other DOE laboratories, universities, and industrial partners. Triage issues, review external contributions, and represent the project at workshops, conferences, and working groups.
• Operate and improve production deployments of MADSci in active autonomous laboratories at Argonne, including monitoring, observability (OpenTelemetry), backups, migrations, and on-call support during experimental campaigns.
• Mentor early-career staff, students, and interns contributing to MADSci and to autonomous-laboratory projects more broadly.
• Contribute to proposals, publications, and outreach describing MADSci and its scientific impact (e.g., journal articles, conference talks, the JOSS publication, documentation).
Qualifications:
Required:
• Bachelor’s degree and 5+ years of experience or Master's and 3+ years in computer science, or a PhD and 0+ years in software engineering, a related computational discipline
• Demonstrated proficiency in modern Python (3.10+), including type-annotated code, packaging, and testing
• Practical experience designing and maintaining production-quality software: version control (Git/GitHub), code review, automated testing, CI/CD, semantic versioning, and structured release management
• Familiarity with at least one web service framework (e.g., FastAPI, Flask, Django) and with HTTP/REST API design
• Working knowledge of relational and/or document databases (e.g., PostgreSQL, MongoDB-compatible stores) and of containerized deployment (Docker, docker compose)
• Strong written and verbal communication skills, including the ability to write clear technical documentation for both developer and end-user audiences
• Demonstrated ability to work effectively as part of a small, cross-disciplinary team and to collaborate with non-software domain experts (scientists, instrument operators, hardware engineers)
• Ability to model Argonne's core values of impact, safety, respect, integrity and teamwork
Preferred:
• Software engineering depth
• Experience designing microservice or service-oriented systems, including service discovery, schema management, and inter-service communication patterns
• Hands-on experience with Pydantic v2, SQLModel/SQLAlchemy, or comparable typed-data and ORM frameworks
• Experience maintaining a multi-package monorepo (e.g., PDM, uv, Poetry workspaces) with shared types and coordinated releases
• Experience with observability tooling: OpenTelemetry, distributed tracing, structured logging, metrics dashboards
• Experience as a maintainer of an open-source project, including triaging external issues, reviewing community contributions, and managing a public roadmap
• Familiarity with frontend development (Vue 3, TypeScript) sufficient to coordinate with frontend collaborators on dashboard and TUI features
• Robotics, lab automation, and self-driving labs
• Experience integrating scientific instruments or laboratory robots with software control systems (e.g., liquid handlers, plate readers, robotic arms, mobile platforms, characterization instruments)
• Familiarity with laboratory automation standards or protocols such as SiLA2, OPC-UA, ROS/ROS 2, AnIML, or vendor-specific instrument SDKs
• Experience building or operating a self-driving laboratory, autonomous experimentation platform, or closed-loop active-learning workflow, in academia, a national lab, or industry
• Familiarity with scientific workflow systems (e.g., Globus Compute, Parsl, Snakemake, Nextflow) and with managing experimental data lifecycles
• Background or coursework in a physical or life science sufficient to communicate fluently with experimental collaborators (e.g., chemistry, materials science, biology, physics)
• Experience deploying software in shared scientific computing environments (HPC clusters, ALCF, lab-edge compute)
• Contributions to DOE, NSF, or other federally funded scientific software projects
• Experience with AI/ML for experimental design (Bayesian optimization, active learning, surrogate models)
• Experience writing or contributing to technical proposals or scientific publications
Company:
Argonne National Laboratory conducts researches in basic science, energy resources, and environmental management. Founded in 1946, the company is headquartered in Lemont, USA, with a team of 1001-5000 employees. The company is currently Late Stage.