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Structural Biologist Jobs in Boston, MA (NOW HIRING)

SupportFinity™

Machine Learning Engineer

Boston, MA · On-site

$140 - $210/hr

Adapt and implement cutting-edge ML architectures for co-folding to augment our extensive internal structural biology expertise and capabilities * Design and deploy active learning frameworks that ...

Moderna, Inc.

Scientist, Protein Design

Cambridge, MA · On-site

Develop biological and structural understanding of assigned targets through literature review, analysis of internal and external data, and discussion with project teams. * Collaborate with cross ...

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All JobsStructural Biologist JobsStructural Biologist Jobs in Boston, MA

Structural Biologist information

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$20

$38

$54

How much do structural biologist jobs pay per hour?

As of Aug 22, 2026, the average hourly pay for structural biologist in Boston, MA is $38.63, according to ZipRecruiter salary data. Most workers in this role earn between $31.63 and $43.94 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a structural biologist?

To thrive as a Structural Biologist, you need a strong background in molecular biology, biochemistry, and protein chemistry, usually supported by a PhD in a relevant field. Proficiency with techniques such as X-ray crystallography, cryo-electron microscopy (cryo-EM), and computational modeling software is typically required. Strong analytical thinking, attention to detail, and effective teamwork are critical soft skills for interpreting complex data and collaborating on research projects. These skills are essential for accurately elucidating biomolecular structures, advancing scientific knowledge, and driving innovation in drug discovery and biotechnology.

What are some common challenges structural biologists face when collaborating on interdisciplinary research projects?

Structural biologists often work closely with computational scientists, chemists, and clinicians to interpret and apply structural data. A common challenge in these collaborations is effectively communicating complex structural information to colleagues outside the field, ensuring that findings are accurately understood and integrated into broader research goals. Additionally, coordinating project timelines and data sharing across diverse teams can require strong organizational skills and adaptability. Building mutual understanding and setting clear expectations at the outset can help overcome these challenges and foster productive interdisciplinary work.

What is the difference between Structural Biologist vs Molecular Biologist?

AspectStructural BiologistMolecular Biologist
Required CredentialsTypically a Ph.D. in biochemistry, biophysics, or related fieldsUsually a Ph.D. or Master's in biology, biochemistry, or related areas
Work EnvironmentResearch labs, universities, biotech companies focusing on 3D structuresLabs, research institutions, focusing on gene and protein functions
Employer & Industry UsagePharmaceuticals, biotech, academia, structural research

While both roles involve biological research, Structural Biologists specialize in determining the 3D structures of biomolecules, often using techniques like X-ray crystallography or cryo-EM. Molecular Biologists focus on understanding gene and protein functions at the molecular level. The two roles often overlap but differ mainly in their focus and methods used.

How much does a structural biologist make?

A structural biologist's salary varies based on experience, education, and location, but typically ranges from $60,000 to $120,000 annually. Entry-level positions may start lower, while experienced professionals with advanced skills in techniques like X-ray crystallography or cryo-EM can earn higher salaries, especially in research or industry settings.

Is structural biology in demand?

Structural biologists are in demand in research institutions, pharmaceutical companies, and biotech firms, as their expertise in techniques like X-ray crystallography and cryo-electron microscopy is essential for drug development and understanding biological mechanisms. The field offers opportunities for employment with advanced degrees and proficiency in specialized tools. Growing interest in personalized medicine and structural analysis continues to drive job opportunities in this area.

What does a structural biologist do?

A structural biologist studies the 3D structures of biological molecules such as proteins, nucleic acids, and complexes using techniques like X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy. Their work helps understand how these molecules function and interact, which can inform drug design and disease research. They often work in research labs, collaborating with chemists and biologists, and require strong skills in biochemistry and molecular biology.
Structural Biologist jobs near you
Infographic showing various Structural Biologist job openings in Boston, MA as of August 2026, with employment types broken down into 86% Full Time, 9% Part Time, 4% Contract, and 1% Nights. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $80,346 per year, or $38.6 per hour.

Cryo-FIB/SEM Staff Scientist, CryoEM Facility

MIT Human Resources

Cambridge, MA • On-site

Full-time

Re-posted 5 days ago

Job description

CRYO-FIB/SEM Staff Scientist, CryoEM Facility, Biology, to lead the adoption of next-generation plasma FIB milling and in situ structural biology as the primary expert for the newly installed HydraBio plasma FIB/SEM; advance cellular and tissue imaging by developing cryo-FIB/ET and volume EM workflows, including fluorescence-guided targeting, precision milling, and lift-out; provide user training, experimental design consultation, and troubleshooting; collaborate on sample preparation, tomography, and data reconstruction; and drive innovative method development and publications; oversee instrument calibration, vendor servicing, and facility infrastructure, including liquid nitrogen and data storage; represent the facility through tours, workshops, and scientific outreach, strengthening cryo-ET and volume EM research across the Cambridge/Boston community.

The full job description is available, here: https://acrobat.adobe.com/id/urn:aaid:sc:US:4001a239-70bd-4d68-837c-15d86f680ace

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Our mission is to advance a vibrant and diverse work community where individuals and groups thrive and contribute to MIT's excellence. We offer Support, Services, and Programs to enhance your work life. We're here to help. MIT is committed to helping employees achieve a healthy balance between their careers and the full lives they lead off-campus. Explore all of MIT's Work & Life resources, including MyLife Services, which provides 24/7 access to a network of experts available to help with life’s challenges.

Industry

Human resource programs administration

Company size

1 - 10 Employees

Headquarters location

Cambridge, MA, US

Year founded

2014

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