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Structural Biologist Jobs in Boston, MA (NOW HIRING)

Harvard University

Postdoctoral Fellow

Cambridge, MA · On-site

$54K - $73K/yr

... research in structural biology of membrane proteins. Our lab investigates the structure, mechanism and evolution of several types of membrane proteins using biochemical, biophysical, and ...

MSD

Sr. Scientist, Generative Protein Design

Cambridge, MA · On-site

$100K - $136K/yr

Integrate AI/ML protein design methods with structural biology and high-throughput experimental screening data to devise and execute de novo protein design and optimization strategies. * Process and ...

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All JobsStructural Biologist JobsStructural Biologist Jobs in Boston, MA

Structural Biologist information

See Boston, MA salary details

$20

$38

$54

How much do structural biologist jobs pay per hour?

As of Aug 22, 2026, the average hourly pay for structural biologist in Boston, MA is $38.63, according to ZipRecruiter salary data. Most workers in this role earn between $31.63 and $43.94 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a structural biologist?

To thrive as a Structural Biologist, you need a strong background in molecular biology, biochemistry, and protein chemistry, usually supported by a PhD in a relevant field. Proficiency with techniques such as X-ray crystallography, cryo-electron microscopy (cryo-EM), and computational modeling software is typically required. Strong analytical thinking, attention to detail, and effective teamwork are critical soft skills for interpreting complex data and collaborating on research projects. These skills are essential for accurately elucidating biomolecular structures, advancing scientific knowledge, and driving innovation in drug discovery and biotechnology.

What are some common challenges structural biologists face when collaborating on interdisciplinary research projects?

Structural biologists often work closely with computational scientists, chemists, and clinicians to interpret and apply structural data. A common challenge in these collaborations is effectively communicating complex structural information to colleagues outside the field, ensuring that findings are accurately understood and integrated into broader research goals. Additionally, coordinating project timelines and data sharing across diverse teams can require strong organizational skills and adaptability. Building mutual understanding and setting clear expectations at the outset can help overcome these challenges and foster productive interdisciplinary work.

What is the difference between Structural Biologist vs Molecular Biologist?

AspectStructural BiologistMolecular Biologist
Required CredentialsTypically a Ph.D. in biochemistry, biophysics, or related fieldsUsually a Ph.D. or Master's in biology, biochemistry, or related areas
Work EnvironmentResearch labs, universities, biotech companies focusing on 3D structuresLabs, research institutions, focusing on gene and protein functions
Employer & Industry UsagePharmaceuticals, biotech, academia, structural research

While both roles involve biological research, Structural Biologists specialize in determining the 3D structures of biomolecules, often using techniques like X-ray crystallography or cryo-EM. Molecular Biologists focus on understanding gene and protein functions at the molecular level. The two roles often overlap but differ mainly in their focus and methods used.

How much does a structural biologist make?

A structural biologist's salary varies based on experience, education, and location, but typically ranges from $60,000 to $120,000 annually. Entry-level positions may start lower, while experienced professionals with advanced skills in techniques like X-ray crystallography or cryo-EM can earn higher salaries, especially in research or industry settings.

Is structural biology in demand?

Structural biologists are in demand in research institutions, pharmaceutical companies, and biotech firms, as their expertise in techniques like X-ray crystallography and cryo-electron microscopy is essential for drug development and understanding biological mechanisms. The field offers opportunities for employment with advanced degrees and proficiency in specialized tools. Growing interest in personalized medicine and structural analysis continues to drive job opportunities in this area.

What does a structural biologist do?

A structural biologist studies the 3D structures of biological molecules such as proteins, nucleic acids, and complexes using techniques like X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy. Their work helps understand how these molecules function and interact, which can inform drug design and disease research. They often work in research labs, collaborating with chemists and biologists, and require strong skills in biochemistry and molecular biology.
Structural Biologist jobs near you
Infographic showing various Structural Biologist job openings in Boston, MA as of August 2026, with employment types broken down into 86% Full Time, 9% Part Time, 4% Contract, and 1% Nights. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $80,346 per year, or $38.6 per hour.

Senior AI Scientist - Drug Discovery & Computational Biology (Hybrid - Boston, MA, USA)

OMG Technology

Boston, MA • On-site

$75/hr

Contractor

Posted 15 days ago

Job description

Senior AI Scientist – Drug Discovery & Computational Biology (Hybrid - Boston, MA, USA)
We are looking to hire a candidate with the mentioned skill sets and experience for one of our clients within the Healthcare Industry. This is a 6+ month contracting role, with potential for extension. This is a HYBRID role.


Key Responsibilities:


We are seeking a highly skilled professional with deep expertise in applying Artificial Intelligence and Machine Learning to drug discovery and development. The ideal candidate will have experience in Drug Discovery & Computational Biology (Must).

The candidate should demonstrate a strong track record of leveraging advanced computational approaches to accelerate therapeutic discovery and possess the ability to collaborate effectively with multidisciplinary research and development teams.


Required Skills/Qualifications:


  • Deep expertise in applying Artificial Intelligence and Machine Learning to drug discovery and development.
  • Experience in Drug Discovery & Computational Biology (Must).
  • AI and machine learning methodologies for drug discovery, including predictive modeling, lead optimization, and translational research applications.
  • Graph machine learning techniques for biological networks, molecular property prediction, target identification, and knowledge graph-based discovery.
  • Virtual cell screening and AI-driven target discovery platforms, with particular focus on rare disease research and therapeutic innovation.
  • AI-driven molecular design for small molecules and biologics (Abs/VHH), including toxicity prediction, off-target assessment, developability analysis, and candidate optimization.
  • Structural biology, including protein structure analysis, molecular interactions, computational modeling, and integration of structural data into drug discovery workflows.
  • Healthcare Domain experience (Must).
  • Ability to collaborate effectively with multidisciplinary research and development teams.


Other Job Details:


  • Job Type: C2C or W2.
  • Duration: 6+ months with high possibility of extension.
  • Pay Rate: $75/hr. on C2C or $65/hr. on W2.
  • Location: Hybrid - Boston, MA, USA.
  • Interviews: Video interviews.
  • Docs required: ID proof will be required.