ZipRecruiter

Log In

1

Stealth Biotech Jobs in California (NOW HIRING)

Output, Inc

AI Technical Recruiter

San Francisco, CA · On-site +1

Output is currently in stealth, operated by a team of repeat founders and biotech veterans with multiple exits in AI x Bio, and backed by top-tier VCs including Y Combinator. You will build Output ...

Orchestra Bio, Inc

Senior Platform Engineer

San Francisco, CA · On-site

$123K - $169K/yr

Founded by early Benchling leaders, we just emerged from stealth with $20M in funding from 8VC, Andreessen Horowitz, Insight Partners, Definition, and Haystack to transform how biotech companies ...

Benchling

AI Partnerships Lead

San Francisco, CA · On-site

$173K - $234K/yr

We are rebuilding biotech for the AI era. When a breakthrough is delayed, the world waits. Getting ... Source, diligence, and place clear bets on the next generation of AI/ML companies, from stealth ...

Orchestra Bio, Inc

Senior Fullstack Engineer

San Francisco, CA · On-site

$144K - $190K/yr

Founded by early Benchling leaders, we just emerged from stealth with $20M in funding from 8VC, Andreessen Horowitz, Insight Partners, Definition, and Haystack to transform how biotech companies ...

Pivotal

Analytical Scientist, Ph.D.

San Diego, CA · On-site

$110K - $140K/yr

San Diego, CA Job Type: Full-Time, Onsite About Us We are an innovative, stealth-mode biotech focused on developing best-in-class delivery for in vivo gene editing. Job Summary We are seeking a ...

next page

Showing results 1-20

All JobsStealth Biotech JobsStealth Biotech Jobs in California

Stealth Biotech information

What are the unique challenges of working at a stealth biotech company?

Working at a Stealth Biotech company often involves operating in a highly confidential environment where active projects and discoveries are not publicly disclosed until specific milestones are achieved. Team members need to balance rigorous scientific work with strict information security protocols, which can add complexity to daily operations. You may encounter rapidly changing priorities and the need to pivot your focus as new data emerges or company strategies shift. Collaboration with a small, skilled team is typical, allowing for significant hands-on experience, but also requires flexibility, resourcefulness, and strong trust among colleagues.

What are the key skills and qualifications needed to thrive in the stealth biotech position, and why are they important?

To thrive in a Stealth Biotech role, candidates typically need a strong background in life sciences or biotechnology, advanced research skills, and usually a graduate-level degree such as a PhD or MS. Familiarity with specialized laboratory equipment, data analysis software, and adherence to regulatory compliance standards like GLP or GMP is often required. Excellent collaboration, adaptability, and the ability to work discreetly are critical soft skills in this environment. These abilities are crucial as the work often involves confidential research and fast-paced innovation within a highly specialized and secretive setting.

What are the most commonly searched types of Stealth Biotech jobs in California?

The most popular types of Stealth Biotech jobs in California are:

What are popular job titles related to Stealth Biotech jobs in California?

For Stealth Biotech jobs in California, the most frequently searched job titles are:

What job categories do people searching Stealth Biotech jobs in California look for?

The top searched job categories for Stealth Biotech jobs in California are:

What cities in California are hiring for Stealth Biotech jobs?

Cities in California with the most Stealth Biotech job openings:

Stealth Biotech jobs near you
Infographic showing various Stealth Biotech job openings in California as of August 2026, with employment types broken down into 100% Full Time. Highlights an 90% In-person, and 10% Remote job distribution.

Senior Process Engineer, Assay Development

San Diego Stealth Startup

San Diego, CA

$131K - $140K/yr

Full-time

Posted 22 days ago

Job description

Location: San Diego, CA

Job Type: Full-Time

Compensation: $131,000 - $140,000

Position Overview

We are seeking a Senior Process Engineer to drive the development, automation, and productionalization of clinical next-generation sequencing (NGS) assays. This is a hands-on individual contributor role focused on translating bench-developed chemistry into robust, automated, audit-ready workflows that are ready for clinical lab deployment.

The Senior Process Engineer will work in close partnership with assay development scientists, automation engineers, quality/regulatory specialists, and laboratory operations to design and qualify automated methods for library preparation, nucleic acid extraction, and sample quantitation and normalization. The role requires a builder's mindset, comfort with ambiguity, and the discipline to apply rigorous engineering practices in an early-stage environment where the process roadmap is still being defined.

Key Responsibilities

  • Develop, optimize, and qualify automated workflows for NGS library preparation.
  • Partner with assay development scientists to transfer bench-developed chemistry onto automation platforms, identifying and resolving robustness, scaling, and operability issues.
  • Apply DOE, SPC, and other statistical tools to characterize process performance, define operating windows, and establish in-process and release specifications.
  • Contribute to reagent and consumable manufacturing and qualification activities, including QC method development and lot release strategy.
  • Execute equipment qualification activities (IQ/OQ/PQ) for automation and ancillary instrumentation in partnership with engineering and lab operations.
  • Support development and maintenance of process documentation, including process maps, equipment lists, and bills of materials, in alignment with design control expectations.
  • Participate in tech transfer of NGS assays to the clinical laboratory, supporting validation activities and resolving process issues that surface during scale-up and deployment.
  • Partner cross-functionally with chemistry, automation, software, quality, and lab operations to drive sustainable process improvements.

Qualifications

  • BS/MS in Chemical Engineering, Bioengineering, Biochemistry, Biotechnology, or a related field.
  • 6+ years of experience in process engineering or process development within clinical diagnostics, NGS, biotech, or other regulated laboratory environments.
  • Hands-on experience developing and optimizing automated laboratory workflows, including direct protocol development on liquid handling platforms.
  • Demonstrated experience supporting clinical or near-clinical NGS assays, including library preparation, nucleic acid extraction, methylation conversion, or sample QC workflows.
  • Prior experience supporting LDT and/or FDA-regulated IVD assay development. Working knowledge of design controls and regulated development frameworks (ISO 13485, IVD or LDT context), with experience operating in a quality-driven environment.
  • Practical fluency in data-driven process development methods — DOE, statistical process control, Gage R&R, root cause analysis.
  • Ability to operate independently across multiple workstreams in an early-stage environment where requirements evolve.
  • Comfort operating in a stealth-stage, resource-constrained environment where processes are being built from the ground up.

Why Join Us

  • Influence the foundational technologies and strategies of a company poised to shape the future of clinical genomics and healthcare.
  • Work in a dynamic, collaborative environment where innovation and scientific rigor are deeply valued.
  • Join a seasoned and multidisciplinary team tackling high-impact problems at the intersection of science and engineering.
  • Competitive compensation and equity package, comprehensive benefits, and flexibility to support work-life integration.

We are an equal opportunity employer. We thrive on diversity and collaboration.