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Statistical Programmer 2 Jobs (NOW HIRING)

Vrtx

Principal Statistical Programmer

Boston, MA · Remote

$149K - $223K/yr

The Principal Statistical Programmer works with management to delegate tasks appropriately, track ... to two days per week; or select 3. On-Site : work five days per week on-site with ad hoc ...

Actalent

Senior Statistical Programmer

Princeton, NJ · Hybrid

$70 - $80/hr

Senior Statistical Programmer The Senior Statistical Programmer will provide comprehensive ... Work Environment This position requires working in the office at least two days a week. The company ...

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Statistical Programmer 2 information

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$84.5K

$147.3K

$249K

How much do statistical programmer 2 jobs pay per year?

As of Sep 10, 2026, the average yearly pay for statistical programmer 2 in the United States is $147,292.00, according to ZipRecruiter salary data. Most workers in this role earn between $125,000.00 and $160,000.00 per year, depending on experience, location, and employer.

What is a statistical programmer 2?

A Statistical Programmer 2 is a mid-level professional who specializes in writing and managing computer programs to analyze and process data, often in clinical research or pharmaceutical settings. They are responsible for generating statistical tables, listings, and figures, as well as validating data and ensuring compliance with regulatory standards. Typically, they work with software like SAS or R and collaborate closely with statisticians, data managers, and clinical teams to support data-driven decision-making. Their role requires a solid understanding of statistical methodologies, programming skills, and industry regulations.

What are the key skills and qualifications needed to thrive as a statistical programmer 2?

To thrive as a Statistical Programmer 2, you need a strong background in statistics, data analysis, and programming languages such as SAS or R, usually supported by a degree in statistics, mathematics, or a related field. Experience with clinical trial data standards (like CDISC SDTM/ADaM), regulatory submission requirements, and data management systems is typically expected. Attention to detail, strong problem-solving skills, and effective communication are essential soft skills that help ensure accuracy and collaboration. These competencies are vital for delivering reliable statistical outputs and supporting successful clinical research and regulatory submissions.

How does a statistical programmer 2 typically collaborate with biostatisticians and clinical teams during a clinical trial project?

As a Statistical Programmer 2, you will frequently work closely with biostatisticians to implement statistical analysis plans, ensuring that data outputs meet regulatory standards and project specifications. Collaboration with clinical teams is also essential for clarifying data requirements, resolving discrepancies, and understanding study protocols. Effective communication and teamwork are crucial, as you may be responsible for translating statistical methods into programming code and explaining technical outputs to non-programmers. This collaborative environment provides opportunities to expand both your technical and interpersonal skills.
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Statistical Programmer 2 jobs near you
Infographic showing various Statistical Programmer 2 job openings in the United States as of September 2026, with employment types broken down into 3% Internship, 86% Full Time, 9% Part Time, 1% Contract, and 1% Nights. Highlights an 84% Physical, 2% Hybrid, and 14% Remote job distribution, with an average salary of $147,292 per year, or $70.8 per hour.

Principal Statistical Programmer

Boston, MA • Remote

Vrtx
See more jobs at Vrtxexternal

$149K - $223K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 15 days ago

Job description

Job Description

General Summary:

The Principal Statistical Programmer works with management to delegate tasks appropriately, track progress, and provide expert technical support to team members. In addition, the Principal Statistical Programmer is a designated member of clinical sub-team(s) in the role of project lead Statistical Programmer.

Key Duties and Responsibilities:

  • Works regularly with advanced features of SAS (including interfacing ability with other software applications and operating system tools)

  • Performs quality control checks of SAS code and output produced by other Statistical Programmers to ensure accuracy and consistency within group

  • Demonstrates in-depth knowledge of clinical development and medical data

  • Solves complex clinical trial reporting problems and demonstrates technical proficiency and exercises judgment in supporting daily operations and ensuring that study tasks are completed accurately and in a timely manner

  • Engages with a variety of other functions, including Statistical Programmers, Biostatisticians, Data Management, and other departments engaged in providing data and submission-related activities, often at Senior Management levels

  • Creates all files, documents, and analyses necessary to support an electronic submission in eCTD format, including ISS/ISE

  • Provides leadership to ensure compliance with Vertex SOP'S and FDA/ICH/GCP regulations

  • Provides technical and project management skills to create, review, and approve documentation required to support data analysis, reporting, and CDlSC data submission

  • Participates in project management cross-functional teams that work on standard operating procedures, guidelines, process improvements, system validation and acquisition, customization, and integration of new tools and technologies

Knowledge and Skills:

  • Proficiency in all SAS language, procedures, and functions commonly used in clinical trial reporting including the Macro language, BASE SAS, SAS/STAT and SAS/GRAPH

  • Intermediate knowledge of CDISC Standards

  • Intermediate knowledge of clinical trials

  • Regulatory submission experiences

  • Effective communication (written and verbal) skills to explain difficult information

Education and Experience:

  • Bachelors degree in a Scientific Discipline

  • Typically requires 5+ for M.S. or above and 8+ years for B.S. years of work experience in Biotech, Pharmaceuticals or Clinical Research Organization


At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$149,200 - $223,800

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Remote-Eligible

Flex Eligibility Status:

In this Remote-Eligible role, you can choose to be designated as:
1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select
2. Hybrid: work remotely up to two days per week; or select
3. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Remote

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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