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Staff Software Jobs in California (NOW HIRING)

Staff Software Engineer

San Diego, CA · On-site

$156 - $233/hr

Staff Software EngineerSkip to main content#Staff Software Engineer page is loaded## Staff Software EngineerApplylocations: US - California - San Diego: US - Remotetime type: Full timeposted on:

Staff Software Engineer

San Mateo, CA · On-site

$158K - $277K/yr

Summary Solution Engineering is looking for a Staff Software Engineer to provide technical leadership across cloud-native services and AI-enabled engineering initiatives. This role is ideal for ...

Staff Software Engineer

San Mateo, CA · On-site

$158K - $277K/yr

Summary Solution Engineering is looking for a Staff Software Engineer to provide technical leadership across cloud-native services and AI-enabled engineering initiatives. This role is ideal for ...

Staff Software Engineer

San Francisco, CA · On-site

$250K - $325K/yr

The Role | Staff Software Engineer As a Staff Software Engineer at Endeavor, you will help optimize our application and make our key business cases run faster. You'll find the bottlenecks in a messy ...

247Hire in Burbank is seeking a hands-on Staff Software Engineer to drive high-impact initiatives at the forefront of emerging technologies. You'll lead prototyping efforts, building scalable proofs ...

247Hire in Burbank is seeking a hands-on Staff Software Engineer to drive high-impact initiatives at the forefront of emerging technologies. You'll lead prototyping efforts, building scalable proofs ...

The Staff Software Engineer will work cross-functionally to build robust and scalable systems, leading technical decision-making and fostering an inclusive team culture. Responsibilities : • Drive ...

Staff Software Engineer Location: Hercules, California Duration: Long term contract As a Staff Software Engineer, you will also provide technical leadership: mentoring junior engineers, driving best ...

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Staff Software information

What is a staff software engineer?

Staff Software Engineers are senior-level engineers who play a key role in designing, developing, and overseeing complex software projects. They typically have extensive experience and are responsible for setting technical direction, mentoring other engineers, and collaborating with cross-functional teams. In addition to coding, they often influence architecture decisions and contribute to overall engineering strategy within an organization.

How does a staff software engineer typically collaborate with cross-functional teams on large-scale projects?

As a Staff Software Engineer, you'll frequently work alongside product managers, designers, and other engineering teams to define technical requirements and ensure alignment on project goals. This role often involves leading technical discussions, mentoring junior engineers, and making architectural decisions that impact multiple teams. Effective communication and the ability to translate complex technical concepts for non-technical stakeholders are crucial. You may also facilitate code reviews and help set engineering best practices across the organization.

What are the key skills and qualifications needed to thrive as a staff software engineer, and why are they important?

To thrive as a Staff Software Engineer, you need advanced software development skills, deep expertise in system architecture, and typically a bachelor’s or master’s degree in computer science or related fields. Proficiency with programming languages (such as Python, Java, or C++), cloud platforms, development frameworks, and version control systems is crucial. Strong leadership, effective communication, and problem-solving abilities set standout staff engineers apart as they guide teams and influence technical direction. These skills and qualities are vital for designing scalable solutions, mentoring peers, and ensuring project success across complex engineering environments.

What is the difference between Staff Software vs Software Engineer?

AspectStaff SoftwareSoftware Engineer
Required credentialsBachelor's or higher in CS or related field; extensive experienceBachelor's or higher in CS or related field; some experience
Work environmentLead complex projects, mentor teams, influence technical strategyDevelop features, fix bugs, collaborate within teams
Employer usageUsed in larger organizations for senior technical rolesCommon entry to mid-level technical roles across industries

Staff Software roles typically involve leading complex projects and mentoring, requiring extensive experience. Software Engineers focus on developing features and collaborating within teams. The roles differ mainly in seniority and scope, with Staff Software positions being more strategic and leadership-oriented.

Infographic showing various Staff Software job openings in California as of August 2026, with employment types broken down into 2% As Needed, 80% Full Time, 13% Part Time, 1% Temporary, and 4% Contract. Highlights an 96% Physical, 2% Hybrid, and 2% Remote job distribution.

Staff Software Engineer

Illumina

San Diego, CA • On-site

$156 - $233/hr

Other

Medical, Dental, Vision, Retirement, PTO

Posted 7 days ago


Illumina rating

8.3

Company rating: 8.3 out of 10

Based on 9 frontline employees who took The Breakroom Quiz

114th of 493 rated machine equipment manufacturers


Job description

Staff Software EngineerSkip to main content#Staff Software Engineer page is loaded## Staff Software EngineerApplylocations: US - California - San Diego: US - Remotetime type: Full timeposted on: Posted Yesterdayjob requisition id: 43096-JOBWhat if the work you did every day could impact the lives of people you know? Or all of humanity?## At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.## Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.## What if the work you did everyday could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, can make a difference. Surrounded by extraordinary people, inspiring leaders, and world-changing projects, you will do more and become more than you ever thought possible.We are searching for a software engineer who is ready to join us in this important mission.Illumina’s Primary Analysis team specializes in designing algorithms and developing software to detect genomic data from signals contained within images. Implementation challenges include managing parallel tasks, optimizing memory accesses, and improving the speed and accuracy of genomic base calling. We develop methods to address these challenges by focusing on high reliability, speed, and completeness of results. We are seeking an exceptional individual to join our team in developing analysis solutions for use by researchers and clinicians worldwide.**Responsibilities:*** Define software architecture solutions for our high-performance signal processing pipelines* Design, develop, debug, and integrate C/C++ software on Linux for multi-threaded applications* Optimize and accelerate software executed on Illumina instruments* Closely interact with the bioinformatics team, instrument design team, test and quality teams* Collaborate in an agile environment to maintain high quality software against established processes* Maintain awareness of industry trends and evaluate applicability of new software and hardware technologies to platform development efforts* Provide technical leadership where needed**Requirements:*** Extensive knowledge and experience with C/C++, Java or C#* Experience in multi-threading, and memory management techniques* Proficient with tools for software debugging and troubleshooting (GDB, etc.)* Proficient with tools for software performance analysis and optimization* Proficient with source control management repositories (such as GIT, SVN, etc.)* Extensive experience writing high quality unit tests against mock objects* Good understanding of object-oriented analysis and design* Strong problem-solving skills**Desired:*** Extensive knowledge and experience in developing software for real-time systems* Experience with image processing algorithms and techniques* Experience with time-series analysis and interpretation of temporal data* Experience with Python and Python visualization libraries* Be customer-focused, team-oriented, and motivated, taking ownership of assigned tasks* Have proven ability to self-manage, as well as manage interdisciplinary relationships* Have proven verbal and written communication skills**Education & Experience:*** BS/MS in Computer Science, EE, Bioinformatics, or related field* 8+ years of professional software development experience#LI-HYBRID### The estimated base salary range for the Staff Software Engineer role based in the United States of America is: $155,600 - $233,400. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‐term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.### We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. #J-18808-Ljbffr

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