Staff Software Engineer Machine Learning Jobs in Houston, TX

At Fuze Health, we put patients first and tirelessly address the most pressing needs in healthcare. We empower millions to digitally connect with care providers, essential health resources and needed treatments – and enable care providers, employers, health plans and life sciences companies to meaningfully enhance quality, outcomes and value. We are dedicated to helping our partners evolve and modernize to meet emerging patient and marketplace needs.

Fuze Health's foundation is built upon the strategic combination of several proven, technology-powered innovators in the digital health, diagnostics, and pharmacy sectors. Our growing portfolio brings together the capabilities of industry leaders including LetsGetChecked, Truepill, and Alto Pharmacy, to create a distinctive, unified force in healthcare. Together, we have the shared vision, advanced capabilities and talented teams to deliver next-generation solutions that patients and healthcare partners need today and into the future.

We are actively recruiting for a Staff Software Engineer. As a Staff Software Engineer at FuzeRx, you are a principal technical leader within our technology organization, responsible for defining the architectural evolution, technical strategy, and engineering standards of our digital pharmacy platforms. This role sits within our core product engineering hierarchy, reporting directly to the Director/VP of Engineering or a Principal Engineer.

Unlike traditional management paths, this is a highly technical individual contributor (IC) role. You will serve as a force multiplier across multiple agile squads, tackling our most complex distributed systems challenges and ensuring our API-driven fulfillment platform is secure, highly scalable, and resilient. By blending deep technical expertise in Ruby on Rails, Python, PostgreSQL, and AWS with a strong understanding of healthcare systems, you will directly influence how millions of patients access vital medications.

• Technical Leadership & Architecture: Define the long-term technical vision and architectural roadmap for FuzeRx's B2B and consumer platforms. Drive decisions around microservices design, API design, database schemas, and data pipelines.

• Engineering Excellence & Code Quality: Lead by example by writing clean, highly optimized, and maintainable code for critical system components. Establish engineering standards, champion rigorous code reviews, and advocate for modern testing practices.

• System Scalability & Performance: Own the reliability and performance of our core platforms. Diagnose and resolve complex systemic issues, optimize heavy PostgreSQL workloads, and architect high-throughput infrastructure on AWS.

• Cross-Squad Force Multiplier: Act as a technical consultant and mentor to engineers across multiple squads. Break down ambiguous, massive technical problems into actionable execution phases that junior and senior engineers can successfully deliver.

• Cross-Functional Collaboration: Partner closely with Product Managers, Pharmacy Operations, and Engineering Managers to evaluate technical feasibility, de-risk complex roadmaps, and align technology choices with business objectives.

• Security & Compliance Safeguarding: Architect systems with privacy by design. Ensure our codebase, data-at-rest, and data-in-transit adhere strictly to healthcare regulations (e.g., HIPAA, SOC2), safeguarding sensitive patient data.

• Innovation & R&D: Evaluate emerging technologies, frameworks, and patterns. Build prototypes and proofs-of-concept (POCs) to derisk new initiatives before they are rolled out to the wider engineering team.

• Education: Bachelor's degree in Computer Science, Software Engineering, or a related technical field (or equivalent practical experience).

• Technical Experience: 8+ years of progressive experience in software engineering, with at least 3+ years acting as a Tech Lead, Architect, or Staff Engineer designing complex, distributed systems.

• Tools & Tech Stack: Expert-level mastery in at least one core language (Ruby on Rails or Python) and deep proficiency with PostgreSQL, TypeScript/JavaScript, and AWS cloud infrastructure (e.g., ECS, RDS, Lambda, VPC).

• System Design Expertise: Proven track record of designing, building, and scaling high-volume API-led transactional or logistical platforms.

• Communication & Influence: Exceptional ability to articulate complex architectural trade-offs to both highly technical engineers and non-technical stakeholders (e.g., clinical, product, and operational leaders).

• Shift / Site Specific Requirements: Standard business hours; available for critical tier-3 escalation architecture support if needed.

• Education: Master's degree in Computer Science or a related technical discipline.

• Industry & Domain Experience: Prior engineering experience within Pharmacy Tech, Digital Health, or highly regulated FinTech/HealthTech environments.

• Healthcare Interoperability: Deep understanding of healthcare data standards, pharmacy management systems, or electronic health record (EHR) integrations.

• Measurable Impact: Proven track record of successfully leading major architecture modernization projects (e.g., monolith-to-services migrations, database overhauls) with zero-downtime within an AWS ecosystem.

Physical requirements for this role include the ability to work at a computer terminal with monitor, keyboard and mouse for extended periods of time, stoop, bend, and reach for equipment and supplies, make frequent repetitive motions required to operate a computer that include the wrists, hands and fingers, and lift, carry, push, pull, and move light objects up to 20 pounds. The role also requires the ability to effectively communicate through verbal interactions, discern auditory information, and visually perceive details to perform essential job functions.

Consistent with the Americans with Disabilities Act (ADA) and similar applicable state laws, it is Fuze Health's policy to provide reasonable accommodation to enable qualified individuals with disabilities to perform essential job functions, unless such accommodation would cause an undue hardship.

Salary Range: $178,400 to $223,000

Location Requirement:

• FuzeRx (Truepill / Fuze Care Services) is limited to individuals residing in the following states: Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Maryland, Massachusetts, Michigan, Minnesota, Missouri, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, Tennessee, Texas, Vermont, Virginia, Washington (WA), Wisconsin

Employment Authorization Requirement: Applicants must be authorized to work for any employer in the U.S. Alto Pharmacy, Fuze Health, LetsGetChecked, and Fuze Care Services can not take over, transfer, or sponsor any visa type at this time.

Full-time employee benefits include: dental, vision, and multiple group medical plans to choose from, a 401(k) retirement savings plan, group life insurance, accidental death and dismemberment (AD&D) insurance, flexible spending account (FSA) and health savings account (HSA), commuter benefits, employer-paid short-term (STD) and long-term disability (LTD) insurance, and additional supplemental insurance plans (spouse life insurance, legal insurance, an employee assistance program, home health testing kits, and a fertility medication discount program). Employees are also provided flexible vacation time, accrued paid sick time, 10 paid holidays, (2 floating holidays for full time non-exempt employees) , and eight weeks of paid parental leave for eligible employees, additional paid weeks for the birthing parent, 4 weeks paid caregiver leave, and a Lifestyle Spending Account allowance each month.

More Benefits Information Here: Fuze Health Benefits Site

The application deadline is July 6, 2026. This application deadline may be extended based on business needs.

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