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Spatial Transcriptomics Jobs in Massachusetts (NOW HIRING)

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Spatial Transcriptomics information

What is spatial transcriptomics?

Spatial transcriptomics is an advanced technique that allows scientists to measure gene expression within the spatial context of tissue samples. Unlike traditional RNA sequencing, which loses information about where each gene is expressed, spatial transcriptomics preserves the physical location of gene activity in tissues. This helps researchers better understand how cells function within their native environments and interact with neighboring cells, which is especially valuable in fields like cancer research, neuroscience, and developmental biology. The method combines microscopy, molecular biology, and computational analysis to produce detailed maps of gene expression.

What are some common challenges faced by professionals working in spatial transcriptomics, and how can they be addressed?

Professionals in spatial transcriptomics often encounter challenges related to handling large, complex datasets and integrating spatial information with gene expression data. Ensuring high-quality sample preparation and mastering advanced imaging or sequencing technologies are also frequent hurdles. These challenges can be addressed by collaborating closely with multidisciplinary teams—including bioinformaticians, molecular biologists, and imaging specialists—and staying up-to-date with the latest software tools and protocols. Continuous learning and effective communication within the team are key to overcoming technical and analytical obstacles in this rapidly evolving field.

What are the key skills and qualifications needed to thrive as a Spatial Transcriptomics Scientist, and why are they important?

To thrive as a Spatial Transcriptomics Scientist, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by an advanced degree in a life science field. Familiarity with spatial transcriptomics platforms (such as 10x Genomics Visium), next-generation sequencing (NGS) technologies, and data analysis tools like R or Python is essential. Strong problem-solving skills, attention to detail, and effective communication are important soft skills for collaborating on interdisciplinary research projects. These skills and qualities are crucial for generating high-quality spatial gene expression data and translating findings into meaningful biological insights.
What are popular job titles related to Spatial Transcriptomics jobs in Massachusetts? For Spatial Transcriptomics jobs in Massachusetts, the most frequently searched job titles are:
What job categories do people searching Spatial Transcriptomics jobs in Massachusetts look for? The top searched job categories for Spatial Transcriptomics jobs in Massachusetts are:
What cities in Massachusetts are hiring for Spatial Transcriptomics jobs? Cities in Massachusetts with the most Spatial Transcriptomics job openings:
Infographic showing various Spatial Transcriptomics job openings in Massachusetts as of July 2026, with employment types broken down into 50% Full Time, and 50% Contract. Highlights an 100% In-person job distribution.
Director, Portfolio Pathology (Multiple Listings)

Director, Portfolio Pathology (Multiple Listings)

Novartis

Cambridge, MA • Hybrid

$204K - $379K/yr

Full-time

Medical, Life, Retirement, PTO

Posted 11 days ago


Novartis rating

7.5

Company rating: 7.5 out of 10

Based on 9 frontline employees who took The Breakroom Quiz

55th of 74 rated pharmaceutical


Job description

Job Description Summary

#LI-Hybrid
Internal Title: Director
Location: Cambridge, MA, USA
Director level toxicologic (anatomic) pathologist to implement innovative drug development strategies for new discoveries and/or initiatives throughout a project lifecycle. Enables impactful experimentation, project initiation, and decision making/progression by leading and empowering an interdisciplinary team or by creating and driving scientific, functional and technical communities surrounding own area of deep expertise and thought leadership. Connects and inspires others around the Novartis Vision.


Job Description

Key Responsibilities:

  • Responsible for generating and evaluating (GLP and Non-GLP) pathology data for assigned studies.

  • Provides leadership, as needed and in fitting with areas of expertise of pathology laboratories, including electron microscopy in Preclinical Safety.

  • Sits on scientific boards, project teams, and advisory committees and may be asked to function as project team representative for preclinical safety.

  • Participate in the study design and in the evaluation and implementation of new procedures to improve the operations. A current knowledge of recent advances is important to achieve optimum results.

  • Responsible for making recommendations toward the development of an annual budget

  • May be asked to assist the management in training the other pathologists

  • May be assigned to projects with more complex design and/or those requiring the most advanced interpretive experience and knowledge.

  • At the conclusion of the study, participates in the data review/analyses and determines target organ toxicity.

  • May participate in projects requiring international involvement as an expert.

  • May be assigned to monitor and review pathology procedures and data during the performance of studies by outside contractors

  • Assists as needed in special technical projects requiring managerial coordination.

Essential Requirements:

  • DVM degree (or equivalent)

  • Pathology training withACVP or ECVP board certification

  • Minimum of 10+ years relevant experience

  • Deep expertise in toxicologic and/or investigative pathology, nonclinical toxicology study design and interpretation.

  • Ability to synthesize and integrate complex molecular datasets (RNA-seq, proteomics, spatial transcriptomics) in the context of tissue biology and nonclinical and translational pathology.

  • Strong cross-functional influence and comfort operating in governance forums and matrixed teams.

  • Commitment to scientific rigor, clear data storytelling, and continuous improvement.

Desirable Requirements:

  • Post Graduate training (PhD, MPH, master's in data science or other relevant degree)

  • Carcinogenicity study design, evaluation and/or interpretation in the context of drug development

The salary for this position is expected to range between: $204,400-$379,600/year

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

To learn more about the culture, rewards and benefits we offer our people click here.


EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.


Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.


Salary Range

$204,400.00 - $379,600.00


Skills Desired

Analytical Thinking, Analytical Thinking, Bioinformatics, Clinical Data Management, Collaboration, Communication Skills (Inactive), Critical Thinking, Data Analysis, Detail-Oriented, Drug Discovery Process, Ethics, Global Project Management, Laboratory (Inactive), Leadership, Lifesciences (Inactive), Management (Inactive), Medical Research, Organization (Inactive), Problem Solving Skills (Inactive), Regulatory Compliance, Report Writing, Strategic Thinking, Team Management, Technical Skills (Inactive), Time Management Skills (Inactive) {+ 2 more}

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