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Spatial Transcriptomics Jobs in Massachusetts (NOW HIRING)

MapLight Therapeutics

Clinical Data Manager

Burlington, MA · On-site

$145K - $160K/yr

We combine cutting-edge technologies including optogenetics, in vivo physiology, and spatial transcriptomics to identify novel drug targets and develop effective therapies to address psychiatric ...

Dana-Farber Cancer Institute

$53K - $72K/yr

The candidate for this position will join a team of computational biologists to work on multi-omic sequencing datasets (DNA, RNA, epigenetic, spatial transcriptomics and spatial proteomics) in the ...

Vizgen Inc

Corporate Controller

Waltham, MA · On-site

$150K - $215K/yr

The company's groundbreaking MERSCOPE product utilizes MERFISH spatial transcriptomics technology to image RNA molecules with high accuracy and unrivaled detection efficiency at subcellular ...

ZS

Patient-Centered Prediction Lead

Boston, MA · On-site

... spatial transcriptomics, methylation, imaging) * Credible as a thought partner with senior R&D leaders on patient-centered prediction topics; able to engage across both scientific and business ...

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Spatial Transcriptomics information

What is spatial transcriptomics?

Spatial transcriptomics is an advanced technique that allows scientists to measure gene expression within the spatial context of tissue samples. Unlike traditional RNA sequencing, which loses information about where each gene is expressed, spatial transcriptomics preserves the physical location of gene activity in tissues. This helps researchers better understand how cells function within their native environments and interact with neighboring cells, which is especially valuable in fields like cancer research, neuroscience, and developmental biology. The method combines microscopy, molecular biology, and computational analysis to produce detailed maps of gene expression.

What are some common challenges faced by professionals working in spatial transcriptomics, and how can they be addressed?

Professionals in spatial transcriptomics often encounter challenges related to handling large, complex datasets and integrating spatial information with gene expression data. Ensuring high-quality sample preparation and mastering advanced imaging or sequencing technologies are also frequent hurdles. These challenges can be addressed by collaborating closely with multidisciplinary teams—including bioinformaticians, molecular biologists, and imaging specialists—and staying up-to-date with the latest software tools and protocols. Continuous learning and effective communication within the team are key to overcoming technical and analytical obstacles in this rapidly evolving field.

What are the key skills and qualifications needed to thrive as a Spatial Transcriptomics Scientist, and why are they important?

To thrive as a Spatial Transcriptomics Scientist, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by an advanced degree in a life science field. Familiarity with spatial transcriptomics platforms (such as 10x Genomics Visium), next-generation sequencing (NGS) technologies, and data analysis tools like R or Python is essential. Strong problem-solving skills, attention to detail, and effective communication are important soft skills for collaborating on interdisciplinary research projects. These skills and qualities are crucial for generating high-quality spatial gene expression data and translating findings into meaningful biological insights.
What are popular job titles related to Spatial Transcriptomics jobs in Massachusetts? For Spatial Transcriptomics jobs in Massachusetts, the most frequently searched job titles are:
What job categories do people searching Spatial Transcriptomics jobs in Massachusetts look for? The top searched job categories for Spatial Transcriptomics jobs in Massachusetts are:
What cities in Massachusetts are hiring for Spatial Transcriptomics jobs? Cities in Massachusetts with the most Spatial Transcriptomics job openings:
Spatial Transcriptomics jobs near you
Infographic showing various Spatial Transcriptomics job openings in Massachusetts as of June 2026, with employment types broken down into 1% Internship, 1% As Needed, 22% Full Time, 71% Part Time, 4% Contract, and 1% Nights. Highlights an 73% Physical, 1% Hybrid, and 26% Remote job distribution.

Associate Director, Statistical Programming

MapLight Therapeutics

Burlington, MA • On-site

$195K - $225K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 14 days ago

Job description

Who We Are: MapLight Therapeutics is a clinical stage biotech company that focuses on drug discovery for central nervous system disorders. We combine cutting-edge technologies including optogenetics, in vivo physiology, and spatial transcriptomics to identify novel drug targets and develop effective therapies to address psychiatric symptoms.
What You'll Do: Reporting to the Senior Director, Statistical Programming, the Associate Director will provide statistical and clinical data programming expertise to manage statistical programming activities that support drug development programs and regulatory submissions. This role involves overseeing the creation, validation, and delivery of programming deliverables, ensuring compliance with industry standards, and fostering cross-functional collaboration with biostatistics, data management, clinical, and regulatory teams.
Responsibilities:
  • Oversee the development and validation of SAS programs to generate datasets (SDTM, ADaM), tables, listings, and figures (TLFs) in compliance with CDISC standards.
  • Ensure the timely and high-quality delivery of programming outputs for regulatory submissions, clinical study reports, and exploratory analyses.
  • Ensure all programming activities align with industry standards (CDISC, ICH, FDA, EMA) and internal SOPs.
  • Programming lead for clinical programs as needed. Hand-on programming work in SAS and other programming languages/tools.
  • Establishes and maintains CRO/vendor partnerships.
  • Act as a liaison between statistical programming and other functions, ensuring clear communication and alignment of goals.
  • Partner with biostatistics, data management, and clinical operations to resolve programming issues and optimize processes.
  • Identify and implement new tools, techniques, and processes to improve efficiency and quality in statistical programming.

Qualifications:
  • Master's degree in statistics, computer science or a related field
  • At least 8 years of statistical programming experience in the pharmaceutical/biotech industry
  • Proven ability to manage CRO relationships and oversee programmed deliverables.
  • Extensive experience in leading statistical programming function for both early and late phase clinical trials, and regulatory submissions (NDA/BLA, MAA)
  • Excellent skills in SAS programming and statistical reporting, knowledge of R and R Shiny desirable
  • In-depth knowledge of CDISC standards for SDTM and ADaM and FDA electronic data submission requirements
  • Familiarity with FDA and ICH regulations and guidelines
  • Excellent written and verbal communication skills, ability to collaborate with a multidisciplinary team and interact effectively in a fast-paced team environment

Location: This is a hybrid role with three days per week in-office in Burlington, Massachusetts.
Compensation for this role may vary within the above range based on many factors including geographic location, candidate experience, and skills. Additional compensation/benefits include annual bonus opportunity, medical, dental, vision, life and AD&D, short term and long term disability, 401(K) plan with match, stock options, flexible non-accrual paid time off, and parental leave.
Salary Range
$195,000-$225,000 USD
EEOC Statement: MapLight Therapeutics is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

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