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Software Engineer Night Shift Remote Jobs in Detroit, MI

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Software Engineering Manager

Detroit, MI · On-site +1

We're looking for software engineers that have started playing project team management and ... Hybrid remote model allows the flexibility to work remotely as much as desired. * Paid time off for ...

Ford Motor Company

Software Test Engineer

Dearborn, MI · On-site +1

$102K - $204K/yr

  • Medical

  • Dental

  • Life

  • PTO

... 5. Remote Vehicle telemetry APIs. 6. Connected vehicle diagnostics including OBD-II, CAN, IP ... Software Test Engineer - positions offered by Ford Motor Company (Dearborn, Michigan). Note, this ...

Techcliff Group

Mulesoft Developer

Dearborn Heights, MI · Remote

$51.50 - $68.25/hr

Experienced MuleSoft Software developer with expertise in designing, developing and testing ... Position can be Remote but Hybrid preferred. Skills Required: Mulesoft, JAVA, Github, Jenkins ...

Birdi

Principal Data Engineer

Plymouth, MI · Remote

$109K - $130K/yr

Remote Employment: Full Time Location: US Seniority: Senior Level Technologies: Tableau, Tableau Server, SSIS, SQL Server, PostgreSQL, Python, SSRS, Azure, Cloud, Git, CI/CD, Terraform ...

THOMSON REUTERS

Lead Research Engineer

Ann Arbor, MI · On-site +1

$100K - $132K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Applying modern software development practices, you will be involved in the entire software ... remote teams. * Be an Agile Person:With a strong sense of urgency and a desire to work in a fast ...

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Software Engineer Night Shift Remote information

See Detroit, MI salary details

$62.9K

$146K

$203.4K

How much do software engineer night shift remote jobs pay per year?

As of Aug 17, 2026, the average yearly pay for software engineer night shift remote in Detroit, MI is $146,043.00, according to ZipRecruiter salary data. Most workers in this role earn between $118,800.00 and $171,300.00 per year, depending on experience, location, and employer.

What does a software engineer night shift remote do?

A Software Engineer Night Shift Remote works primarily during nighttime hours, often from home or another remote location, to design, develop, test, and maintain software applications. Their responsibilities are similar to those of daytime software engineers but they may also address urgent technical issues, perform system maintenance, or support global teams operating in different time zones. Working remotely at night can help companies provide 24/7 support, meet project deadlines, or collaborate with international staff. This role requires strong technical skills, self-motivation, and effective communication, as most collaboration will occur online.

What are the key skills and qualifications needed to thrive as a software engineer night shift remote?

To thrive as a Software Engineer Night Shift Remote, you need strong programming skills, a solid understanding of software development methodologies, and typically a degree in computer science or related field. Familiarity with version control systems like Git, cloud platforms, and remote collaboration tools such as Slack or Jira is essential. Excellent problem-solving abilities, self-motivation, and effective communication are crucial soft skills, especially when working independently during off-hours. These skills and qualities ensure productivity, code quality, and seamless collaboration with distributed teams despite the challenges of remote night shift work.

What are some common challenges faced by remote software engineers working the night shift, and how can they be addressed?

Remote software engineers on the night shift often encounter challenges such as coordinating with daytime teams, managing communication across different time zones, and maintaining a healthy work-life balance due to unconventional hours. To address these issues, it's important to establish clear communication protocols, make use of collaborative tools for asynchronous work, and set personal routines that support both productivity and well-being. Regular check-ins with team members and proactive documentation can also help ensure projects stay on track despite time differences.

What are popular job titles related to Software Engineer Night Shift Remote jobs in Detroit, MI?

For Software Engineer Night Shift Remote jobs in Detroit, MI, the most frequently searched job titles are:

What job categories do people searching Software Engineer Night Shift Remote jobs in Detroit, MI look for?

The top searched job categories for Software Engineer Night Shift Remote jobs in Detroit, MI are:

What cities near Detroit, MI are hiring for Software Engineer Night Shift Remote jobs?

Cities near Detroit, MI with the most Software Engineer Night Shift Remote job openings:

Software Engineer Night Shift Remote jobs near you
Infographic showing various Software Engineer Night Shift Remote job openings in Detroit, MI as of August 2026, with employment types broken down into 87% Full Time, and 13% Contract. Highlights an 100% Remote job distribution, with an average salary of $146,043 per year, or $70.2 per hour.

Bioinformatics Software Engineer

micro1 AI

Sterling Heights, MI • Remote

$80 - $110/hr

Part-time

Posted 15 days ago

Job description

Role Title: Computational Biology & Cheminformatics Expert


Role Type: Contractor


Location: Remote


micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer’s computational drug discovery project. In this role, you'll apply your expertise to help train next-generation AI systems. Your work will shape how models learn, reason, and perform through high-quality, real-world input. No prior experience in AI is required — your domain knowledge is what matters.


Scope of Work

  1. Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods.
  2. Curate, annotate, and validate chemical and biological datasets (e.g., ChEMBL, PubChem, DrugBank) to support AI-driven discovery platforms.
  3. Evaluate compound-target interactions, ADMET properties, and lead optimization strategies by integrating chemical, biological, and clinical data sources.
  4. Provide expert insights on structure-activity and structure-property relationships (SAR/SPR), medicinal chemistry approaches, and experimental design considerations.
  5. Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios.
  6. Develop reproducible environments (e.g., using Docker) and automated testing pipelines to ensure task correctness and solvability.
  7. Assess and review AI-generated outputs for scientific rigor, accuracy, and practical relevance, delivering detailed written feedback and recommendations.


Preferred Qualifications

  1. Advanced expertise in Computational Biology, Cheminformatics, Medicinal Chemistry, Biochemistry, or related fields; advanced degree (PhD, MSc, PharmD) highly valued but not strictly required.
  2. Strong coding proficiency in Python (beyond analysis scripts), with hands-on experience building tools, pipelines, or testable code; familiarity with Git, GitHub, and Docker.
  3. Extensive experience with cheminformatics toolkits and platforms such as RDKit, KNIME, Schrödinger, OpenEye, or MOE.
  4. Proven track record in small-molecule drug discovery, SAR/QSAR evaluation, ADMET prediction, or virtual screening workflows.
  5. Comfort working with public chemical and bioactivity databases and integrating diverse datasets for scientific analysis.
  6. Demonstrated ability to clearly communicate complex chemical and biological concepts in written feedback and reports.
  7. Experience participating in multidisciplinary and/or remote projects; familiarity with AI-assisted coding tools is a plus.

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