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Single Molecule Microscopy Jobs in Michigan (NOW HIRING)

Bruker

Automation Chemist

Detroit, MI · On-site

$125K/yr

... molecular and cell biology research, in applied and biopharma applications, in microscopy, as well ... spatial and single-cell biology, structural and condensate biology, as well as in clinical ...

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Single Molecule Microscopy information

What is single molecule microscopy?

Single molecule microscopy is an advanced imaging technique that allows scientists to observe and analyze individual molecules in real time, often within living cells. Unlike traditional microscopy, which looks at the collective behavior of many molecules, this method provides detailed insights into molecular interactions, dynamics, and functions at the single-molecule level. It is widely used in biophysics, chemistry, and cell biology to study processes such as protein folding, enzyme activity, and molecular transport. This technique requires highly sensitive equipment and specialized fluorescent labeling to detect and track single molecules with great precision.

What are the key skills and qualifications needed to thrive as a single molecule microscopy specialist, and why are they important?

To thrive in Single Molecule Microscopy, you need a strong background in physics, chemistry, or biology, typically with an advanced degree and experience in microscopy techniques. Familiarity with advanced fluorescence microscopy systems, data analysis software (such as ImageJ or MATLAB), and often certifications in laboratory safety are important. Attention to detail, problem-solving abilities, and effective communication help in troubleshooting experiments and collaborating with multidisciplinary teams. These skills are essential for generating accurate data, driving scientific discovery, and ensuring the reliability of experimental results.

What is the difference between Single Molecule Microscopy vs Fluorescence Microscopist?

AspectSingle Molecule MicroscopyFluorescence Microscopist
Required CredentialsAdvanced microscopy training, possibly PhD in biology or physicsSimilar; microscopy experience, often with a background in biology or chemistry
Work EnvironmentResearch labs, academic institutions, biotech companiesResearch labs, hospitals, biotech firms
Industry UsageSpecialized research in molecular biology, biophysicsBroad applications in cell biology, medical research

Single Molecule Microscopy and Fluorescence Microscopist roles share similar credentials and work environments, but Single Molecule Microscopy focuses on observing individual molecules, requiring specialized techniques. Fluorescence Microscopists often work with broader fluorescence imaging, making the roles distinct yet related in microscopy expertise.

What are some common challenges faced by single molecule microscopy researchers, and how can they be addressed?

Single molecule microscopy researchers often encounter challenges such as minimizing background noise, achieving high-resolution imaging, and ensuring sample stability during prolonged observations. Addressing these issues typically involves optimizing sample preparation protocols, using advanced imaging techniques like Total Internal Reflection Fluorescence (TIRF) microscopy, and implementing robust data analysis tools. Collaborating closely with physicists, chemists, and bioinformaticians can also help troubleshoot technical hurdles and improve experimental outcomes.
What are popular job titles related to Single Molecule Microscopy jobs in Michigan? For Single Molecule Microscopy jobs in Michigan, the most frequently searched job titles are:
What job categories do people searching Single Molecule Microscopy jobs in Michigan look for? The top searched job categories for Single Molecule Microscopy jobs in Michigan are:
What cities in Michigan are hiring for Single Molecule Microscopy jobs? Cities in Michigan with the most Single Molecule Microscopy job openings:
Single Molecule Microscopy jobs near you

Postdoctoral Researcher in Cell and Molecular Biology / Virology

University of Michigan

Ann Arbor, MI • On-site

$63K - $70K/yr

Full-time

Posted 29 days ago

University Of Michigan rating

8.1

Company rating: 8.1 out of 10

Based on 145 frontline employees who took The Breakroom Quiz

161st of 618 rated colleges and universities

Job description

How to Apply
Interested individuals should email a single pdf file including a cover letter outlining the applicant's research and career goals and why the Maurer Lab is a good fit, CV including contact information for three references, and a copy of at least one representative research publication to Dr. Maurer at [email protected] and cc Dr. Xiao, our Senior Scientist, at [email protected] . Applications will be reviewed as they are received, and only applications that follow the submission guidelines will be considered.
Job Summary
The Maurer Lab in the Department of Biophysics is seeking a highly motivated Postdoctoral Researcher to contribute to ongoing research projects and start recently funded new projects within the scope of adeno-associated viral vector biology. Start dates are flexible, from immediately to May 2027.
The Maurer Lab is within the Biophysics Program in the College of Literature, Science, and the Arts at the University of Michigan, Ann Arbor. We are also affiliated with the Microbiology and Immunology Department at the University of Michigan Medical School. The successful candidate will join a rich and collaborative research environment that spans these adjacent campuses, with many opportunities for professional development.
This is a one-year appointment, with anticipated extension for a second year. All extensions for a second year or beyond are contingent upon satisfactory performance, availability of work and the availability of funding. International applicants are welcome, but we are not able to sponsor an H1B Visa. Additionally, we encourage applicants to apply for the Michigan Pioneer Fellows Program , which provides supplementary salary and outstanding professional development opportunities. Dr. Maurer will help prepare your application.
Responsibilities*
Responsibilities include contributing to project design, collection and analysis of data, manuscript and grant writing, co-mentoring undergraduate and graduate students with Dr. Maurer, and presenting research at regional, national, and international conferences.
Required Qualifications*
The successful candidate will have expertise in one or more of the following specific areas:
  • Plasmid library cloning and screening (pooled and/or arrayed)
  • Virology (especially DNA viruses)
  • Mammalian gene regulation
  • Chromatin structure and function
  • DNA replication and/or repair
  • Cryo-Electron Tomography

Applicants should hold (or be nearing completion of) a PhD in Biological Sciences, Virology/Microbiology/Immunology, Biophysics, Biomedical Sciences/Engineering, or a related field. In addition to the required expertise, preferred skills include: mammalian cell culture, molecular cloning, flow cytometry, CRISPR/Cas9 based genetic perturbations, and microscopy techniques including confocal fluorescent and live imaging.
A Ph.D. is required on or before the start date.
Modes of Work
Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes .
Background Screening
The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks are performed in compliance with the Fair Credit Reporting Act.
U-M EEO Statement
The University of Michigan is an Equal Opportunity Employer. We are committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants, including protected veterans and individuals with disabilities.
Job Detail
Job Opening ID
280029
Working Title
Postdoctoral Researcher in Cell and Molecular Biology / Virology
Job Title
RESEARCH FELLOW
Work Location
Ann Arbor Campus
Ann Arbor, MI
Modes of Work
Onsite
Full/Part Time
Full-Time
Regular/Temporary
Regular
FLSA Status
Exempt
Organizational Group
College Of Lsa
Department
LSA Biophysics
Posting Begin/End Date
7/14/2026 - 10/11/2026
Salary
$63,480.00 - $70,000.00
Career Interest
Research Fellows

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About University of Michigan

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The University of Michigan (U-M), based in Ann Arbor, MI, US, is one of America's most esteemed institutions in higher education. Established in 1817, it presides in the industry of education and research, providing a range of services including undergraduate, graduate, and professional education programs. Complementing this is an extensive research activity that has significantly contributed to various fields, from healthcare to engineering, humanities to sports. Upholding its mission "to serve the people of Michigan and the world through preeminence in creating, communicating, preserving and applying knowledge, art, and academic values", U-M consistently ranks among the top universities globally, a testament to its tradition of excellence in learning and research, and a deep commitment to innovation and discovery.

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Company size

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Headquarters location

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Year founded

1817

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