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Single Cell Spatial Transcriptomics Jobs in Minnesota

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Single Cell Spatial Transcriptomics information

What are the key skills and qualifications needed to thrive as a single cell spatial transcriptomics scientist, and why are they important?

To thrive as a Single Cell Spatial Transcriptomics Scientist, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by an advanced degree (PhD or MSc) in a relevant field. Familiarity with high-throughput sequencing platforms, spatial transcriptomics technologies (like 10x Genomics Visium or NanoString GeoMx), and data analysis tools such as R or Python is essential. Critical thinking, problem-solving, and effective communication are crucial soft skills for interpreting complex data and collaborating in multidisciplinary teams. These skills and qualities are vital for generating reliable insights into cellular function and spatial organization, which drive innovative research and discovery.

What are the typical challenges faced by professionals working in single cell spatial transcriptomics, and how can they be addressed?

Professionals in Single Cell Spatial Transcriptomics often encounter challenges related to handling large, complex data sets and integrating spatial information with single-cell transcriptomic profiles. These tasks demand strong computational skills and close collaboration with bioinformaticians and other researchers. Effective communication within interdisciplinary teams is essential to ensure experimental design aligns with downstream analysis needs. Staying updated with rapidly evolving technologies and best practices also helps professionals overcome technical hurdles and produce reliable, high-impact results.

What is single cell spatial transcriptomics?

Single cell spatial transcriptomics is a cutting-edge technique that allows researchers to analyze gene expression in individual cells while preserving their spatial location within a tissue. This method combines the high-resolution insights of single-cell RNA sequencing with spatial information, enabling scientists to understand how cells interact and organize within their native environments. It is widely used in biomedical research to study tissue architecture, disease mechanisms, and cellular heterogeneity.
What are popular job titles related to Single Cell Spatial Transcriptomics jobs in Minnesota? For Single Cell Spatial Transcriptomics jobs in Minnesota, the most frequently searched job titles are:
What job categories do people searching Single Cell Spatial Transcriptomics jobs in Minnesota look for? The top searched job categories for Single Cell Spatial Transcriptomics jobs in Minnesota are:
What cities in Minnesota are hiring for Single Cell Spatial Transcriptomics jobs? Cities in Minnesota with the most Single Cell Spatial Transcriptomics job openings:
Infographic showing various Single Cell Spatial Transcriptomics job openings in Minnesota as of August 2026, with employment types broken down into 1% Locum Tenens, 78% Full Time, 17% Part Time, and 4% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution.

Post-Doctoral Associate - Noel Lab, Department of Neuroscience

University of Minnesota

Minneapolis, MN • On-site

$61K - $71K/mo

Full-time

Medical, Dental, Life

Re-posted 16 days ago


Job description

About the Job
 

The Noel Lab (noel-lab.org) in the Department of Neuroscience at the University of Minnesota is seeking highly motivated Postdoctoral Associates to join our team. Funded by the Simons Foundation), these positions offer an exciting opportunity to conduct cutting-edge research at the intersection of systems neuroscience and computational modeling. 

Our lab is broadly interested in Bayesian inference, perception, multisensory integration, spatial navigation, sensorimotor loops, embodied cognition, and computational psychiatry. We work across levels of analysisfrom single neurons to human behaviorusing both rodent and human models. This position will focus primarily on rodent research, though exceptional candidates with expertise in human cognitive neuroscience are encouraged to apply.
Position Overview

Successful candidates will lead projects involving:
Large-scale neurophysiology (e.g., Neuropixels recordings) in awake, behaving rodents.
Computational modeling and advanced data analysis.
 

At least one role will be embedded within the newly launched Simons Collaboration on Ecological Neuroscience (SCENE)a multi-species, international consortium exploring ecological behaviors across rodents, bats, non-human primates, and humans (https://www.simonsfoundation.org/2025/04/24/simons-foundation-launches-collaboration-on-ecological-neuroscience/).
 

Collaborative Network
You will engage with a global team of scientists, including but not limited to:
Jan Zimmermann (University of Minnesota)
Mate Lengyel (Cambridge)
Daniel Wolpert (Columbia)
Cris Neill (University of Oregon)
Andreas Tolias (Stanford)
Alexander & Mackenzie Mathis (EPFL)
Constantin Rothkopf (TU Darmstadt)
Nanthia Suthana (Duke)
 

Opportunities for travel, data sharing, and joint publications across sites will be plentiful.
Job Responsibilities

Research (95% effort)
Design and conduct innovative experiments (e.g., neurophysiology data collection)
Build and maintain behavioral and neurophysiology rigs (head-fixed and freely-moving paradigms, including video-tracking)
Rodent surgeries
Analyze data and contribute to computational models
Draft high-quality figures, manuscripts, and grant materials
Present findings at scientific meetings
Mentoring and Instruction (5% effort)
Mentor students and foster a dynamic, collaborative lab culture.
Maintain proper documentation and keep standard operating procedures up to date.
Details
Start Date: July 1, 2025 (negotiable)

Qualifications
 

What We're Looking For


Required Qualifications
Ph.D. in Neuroscience, Biomedical Engineering, or a related field
Strong publication record
Interest in understanding perception and decision-making in real-world contexts
Excellent written and verbal communication skills in English
Proficiency in MATLAB and/or Python
Hands-on experience with rodent behavior and surgeries
Expertise in large-scale neurophysiology and histology
Skilled in single-cell/population data analysis (e.g., GLMs, decoding)
Preferred Qualifications
Background in machine learning or computational modeling (Bayesian methods, neural networks, etc.)
Experience with marker-less video tracking and computer vision
Experience with CAD design and 3D printing
Familiarity with relational databases (e.g., SQL)
Demonstrated success in collaborative research environments

About the Department
 

Neuroscience is the scientific study of the nervous system. It is an interdisciplinary science that collaborates with other fields such as chemistry, computer science, engineering, linguistics, mathematics, medicine and allied disciplines, philosophy, physics, and psychology.

The Department of Neuroscience is committed to providing excellence in research, education, and public service. The Department of Neuroscience is part of the University of Minnesota's Medical School.
 

Pay and Benefits
 

Pay Range: $61,008 - $71,532 annually; depending on education/qualifications/experience

Please visit the Benefits for Postdoctoral Candidates website for more information regarding benefit eligibility.

  • Competitive wages, paid holidays, and generous time off
  • Continuous learning opportunities through professional training
  • Medical, dental, and pharmacy plans
  • Healthcare and dependent care flexible spending accounts
  • University HSA contributions
  • Disability and life insurance
  • Employee wellbeing program
  • Financial counseling services
  • Employee Assistance Program with eight sessions of counseling at no cost
How To Apply
 

Applications must be submitted online.  To be considered for this position, please click the Apply button and follow the instructions.  You will have the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.  

This position requires that you attach: CV (including publications) and a Cover Letter indicating:

Your preferred starting date
Your scientific interests and ambitions for the future
Dates (and time) at which you would be available for a 30 minute zoom interview.
Who may be able to provide a reference letter (letter not required at this stage). 

Please contact Dr. Jean-Paul Noel Noelx071@umn.edu with any questions

This position will remain open until filled.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

Diversity
 

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission.  The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression.  To learn more about diversity at the U:  http://diversity.umn.edu

Employment Requirements
 

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

About University of Minnesota
 

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of Americas Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).