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Single Cell Spatial Transcriptomics Jobs in Connecticut

The Jackson Laboratory

Associate Scientist

Farmington, CT

$69.71K - $90.62K/yr

The Associate Scientist will serve as the platform lead for Xenium spatial transcriptomics projects at Single Cell Biology Lab (SCBL) within The Jackson Laboratory for Genomic Medicine, ensuring the ...

The Jackson Laboratory

Associate Scientist

Farmington, CT · On-site

$69.71K - $90.62K/yr

The Associate Scientist will serve as the platform lead for Xenium spatial transcriptomics projects at Single Cell Biology Lab (SCBL) within The Jackson Laboratory for Genomic Medicine, ensuring the ...

The Jackson Laboratory

Automation Engineer

Farmington, CT · On-site

$65.02K - $108.86K/yr

The SCBL is a core facility enabling the research community with advanced single-cell omics, spatial profiling, and high-content functional screening platforms. This role is central to the lab ...

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Single Cell Spatial Transcriptomics information

What are the key skills and qualifications needed to thrive as a Single Cell Spatial Transcriptomics Scientist, and why are they important?

To thrive as a Single Cell Spatial Transcriptomics Scientist, you need a strong background in molecular biology, genomics, and bioinformatics, typically supported by an advanced degree (PhD or MSc) in a relevant field. Familiarity with high-throughput sequencing platforms, spatial transcriptomics technologies (like 10x Genomics Visium or NanoString GeoMx), and data analysis tools such as R or Python is essential. Critical thinking, problem-solving, and effective communication are crucial soft skills for interpreting complex data and collaborating in multidisciplinary teams. These skills and qualities are vital for generating reliable insights into cellular function and spatial organization, which drive innovative research and discovery.

What are some typical challenges faced by professionals working in Single Cell Spatial Transcriptomics, and how can they be addressed?

Professionals in Single Cell Spatial Transcriptomics often encounter challenges related to handling large, complex data sets and integrating spatial information with single-cell transcriptomic profiles. These tasks demand strong computational skills and close collaboration with bioinformaticians and other researchers. Effective communication within interdisciplinary teams is essential to ensure experimental design aligns with downstream analysis needs. Staying updated with rapidly evolving technologies and best practices also helps professionals overcome technical hurdles and produce reliable, high-impact results.

What is single cell spatial transcriptomics?

Single cell spatial transcriptomics is a cutting-edge technique that allows researchers to analyze gene expression in individual cells while preserving their spatial location within a tissue. This method combines the high-resolution insights of single-cell RNA sequencing with spatial information, enabling scientists to understand how cells interact and organize within their native environments. It is widely used in biomedical research to study tissue architecture, disease mechanisms, and cellular heterogeneity.
What are popular job titles related to Single Cell Spatial Transcriptomics jobs in Connecticut? For Single Cell Spatial Transcriptomics jobs in Connecticut, the most frequently searched job titles are:
What job categories do people searching Single Cell Spatial Transcriptomics jobs in Connecticut look for? The top searched job categories for Single Cell Spatial Transcriptomics jobs in Connecticut are:
Single Cell Spatial Transcriptomics jobs near you
Functional Genomics Scientist III

Functional Genomics Scientist III

Astrix Inc

Ridgefield, CT • On-site

$47 - $49/hr

Full-time

Posted 26 days ago

Job description

Pay Rate Low: 47 | Pay Rate High: 49
Our client, a leading global pharmaceutical company, is looking for a skilled Functional Genomics Scientist III to join their team in Fairfield County, CT! This is a great opportunity to join a leading pharmaceutical company!
Job Type: 1 year contract
Pay rate: $47/hr. - $49/hr.
Location: Fairfield County, CT
Position Summary
We are seeking a highly motivated Functional Genomics Scientist III with strong experience in molecular and cell biology to design, develop, and execute advanced functional genomics assays. The ideal candidate will have hands-on expertise in CRISPR-based genome editing, next-generation sequencing library preparation, and single-cell technologies.
Key Responsibilities
  • Design, develop, and execute functional genomics assays, including CRISPR-based genome editing workflows.
  • Perform CRISPR experiments including guide RNA design, RNP delivery, transfection/infection, selection of edited cells, and validation of knockouts/knock-ins.
  • Conduct next-generation sequencing (NGS) library preparation for genomics and transcriptomics applications.
  • Perform single-cell sequencing workflows, including sample preparation, library generation, and quality control.
  • Implement and support advanced assays such as Perturb-seq, CITE-seq, and spatial transcriptomics.
  • Maintain accurate and detailed laboratory documentation in compliance with internal policies.
  • Define and execute quality control (QC) procedures to ensure data reliability and reproducibility.
  • Operate, maintain, and troubleshoot laboratory equipment.
  • Provide technical guidance and training to research scientists on functional genomics technologies.
  • Monitor scientific literature to identify new methods, tools, and best practices in functional genomics.

Required Qualifications
  • Master's degree in Molecular Biology, Cell Biology, Functional Genomics, or a related field with 4+ years of hands-on laboratory experience.
  • Proven experience with CRISPR genome editing, including guide RNA design, transfection/infection, edited cell selection, and knockout/knock-in validation.
  • Hands-on experience with next-generation sequencing (NGS) library preparation.
  • Experience with single-cell technologies, including sample preparation, library generation, and quality control.
  • Proficiency in molecular biology techniques such as qPCR, Western blotting, cloning, and gel electrophoresis.
  • Strong cell culture skills, including maintaining multiple cell lines and performing transfections using sterile technique.
  • Ability to troubleshoot functional genomics experiments and work effectively in a collaborative, multidisciplinary environment.
  • Experience with lab automation and handling multiple experimental workflows simultaneously is a plus.
*This job description is a complete list of all desired skills, but not all are required. We strongly encourage candidates who have some of the skills to apply. We look forward to a conversation to learn more about you! *
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