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Senior Systems Engineer Jobs in Rochester, NH (NOW HIRING)

Lonza

Systems Engineer, Level 3

Portsmouth, NH · On-site

System Engineer, Level 3 Location: On-site, Portsmouth, NH. Relocation assistance is available for eligible candidates and their families, if needed. The Systems Engineer will support ongoing Lonza ...

Lonza

Systems Engineer, Level 3

Portsmouth, NH

System Engineer, Level 3 Location: On-site, Portsmouth, NH. Relocation assistance is available for eligible candidates and their families, if needed. The Systems Engineer will support ongoing Lonza ...

Symbotic LLC

System Engineer

Raymond, NH · On-site

$80 - $100/hr

The System Engineer focuses on troubleshooting, maintaining and stabilizing complex ... systems (e.g., Maximo) and internal tools. * Act as a senior technical escalation point during ...

Lonza

Systems Engineer, Level 3

Portsmouth, NH · On-site

Lonza is a global leader in life sciences manufacturing, and they are seeking a Systems Engineer to support ongoing operations through technical assistance with computerized systems infrastructure.

Biopharma Careers

Systems Engineer (R2-R4)

Concord, NH · On-site

$80 - $100/hr

Eli Lilly and Company seeks a Systems Engineer (R2-R4) to implement our next-generation Manufacturing Execution System (MES). Ensure alignment of manufacturing sites' strategic milestones and serve ...

SAIC

Senior Network Engineer

Kittery, ME · On-site

$120K - $160K/yr

ORA_ON_SITE Description SAIC is seeking a Senior Network Engineer to support the Portsmouth Naval ... This initiative leverages advanced technologies and integrates critical defense systems to optimize ...

SAIC

Senior Network Engineer

Kittery, ME

$120K - $160K/yr

ORA_ON_SITE Description SAIC is seeking a Senior Network Engineer to support the Portsmouth Naval ... This initiative leverages advanced technologies and integrates critical defense systems to optimize ...

Lonza

Systems Development Engineer II

Portsmouth, NH · On-site

Systems Development Engineer II Location: On-site, Portsmouth, NH. Relocation assistance is available for eligible candidates and their families, if needed. The Systems Engineer will be responsible ...

SAIC

Senior Network Engineer

Kittery, ME · On-site

$120K - $160K/yr

Description SAIC is seeking a Senior Network Engineer to support the Portsmouth Naval Shipyard ... This initiative leverages advanced technologies and integrates critical defense systems to optimize ...

Lonza

Systems Development Engineer II

Portsmouth, NH · On-site

Systems Development Engineer II Location: On-site, Portsmouth, NH. Relocation assistance is available for eligible candidates and their families, if needed. The Systems Engineer will be responsible ...

Lonza

Systems Development Engineer II

Portsmouth, NH · On-site

Systems Development Engineer II Location: On-site, Portsmouth, NH. Relocation assistance is available for eligible candidates and their families, if needed. The Systems Engineer will be responsible ...

Lonza

Systems Development Engineer II

Portsmouth, NH · On-site

Systems Development Engineer II Location: On-site, Portsmouth, NH. Relocation assistance is available for eligible candidates and their families, if needed. The Systems Engineer will be responsible ...

Lonza

Systems Development Engineer II

Portsmouth, NH · On-site

Systems Development Engineer II Location: On-site, Portsmouth, NH. Relocation assistanceis available for eligible candidates and their families, if needed.The Systems Engineerwill be responsible ...

Lonza

Systems Development Engineer II

Portsmouth, NH · On-site

$100 - $125/hr

Serve as primary technical point of contact for MES-related system incidents, working closely with production, automation engineering teams, and quality to minimize downtime. Support connectivity ...

Wilcox Industries

Senior Firmware Engineer

Newington, NH · On-site

$123K - $163K/yr

Wilcox develops innovative, world class electro-mechanical combat systems for today's warfighters and law enforcement officers. Senior Firmware Engineers are a core component of the development team ...

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Showing results 21-40

All JobsSystems Engineer JobsSenior Systems Engineer JobsSenior Systems Engineer Jobs in Rochester, NH

Senior Systems Engineer information

See Rochester, NH salary details

$54.8K

$122.1K

$172.3K

How much do senior systems engineer jobs pay per year?

As of Sep 7, 2026, the average yearly pay for senior systems engineer in Rochester, NH is $122,077.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,300.00 and $140,000.00 per year, depending on experience, location, and employer.

What is a senior systems engineer?

A senior systems engineer is an IT (information technology) professional tasked with designing and maintaining network systems and security. Examples include large server or storage systems, computer networks, and mainframes. As a systems engineer, your primary duties are to oversee the daily operations of your facility and lead a team of engineers in designing new systems to replace old ones. You may work for a company that provides engineering services and solutions for other businesses, or you may be part of a large university or other institution's IT department. Skills needed for the career include the ability to work independently, leadership, and analytical problem-solving. A bachelor’s degree in electrical engineering or IT and significant experience in a lower systems engineering position are essential qualifications.

What are the key skills and qualifications needed to thrive as a senior systems engineer, and why are they important?

To thrive as a Senior Systems Engineer, you need expertise in systems architecture, troubleshooting, and network administration, typically supported by a degree in computer science or a related field and several years of relevant experience. Familiarity with virtualization platforms, cloud services (like AWS or Azure), automation tools (such as Ansible or PowerShell), and certifications like CompTIA, Microsoft, or Cisco are often required. Outstanding problem-solving, communication, and project management skills help you lead initiatives and collaborate effectively across teams. These competencies are crucial for ensuring system reliability, scalability, and security in complex IT environments.

What are some common challenges faced by senior systems engineers when integrating new technologies into existing infrastructure?

Senior Systems Engineers often encounter challenges such as ensuring compatibility between legacy systems and new technologies, minimizing downtime during migrations, and addressing unforeseen security vulnerabilities. Effective integration requires thorough planning, cross-team collaboration, and detailed testing to avoid disruptions to business operations. Staying current with emerging technologies and adopting best practices for change management are essential for overcoming these challenges and ensuring smooth implementation.

What is the difference between Senior Systems Engineer vs Systems Administrator?

AspectSenior Systems EngineerSystems Administrator
CertificationsCompTIA Security+, Cisco CCNA, Microsoft certificationsCompTIA A+, Network+, Microsoft certifications
Work EnvironmentDesigning, implementing, and troubleshooting complex systemsManaging daily system operations and user support
Industry UsageIT, technology, enterprise environmentsIT support, small to medium businesses

While both roles involve working with IT systems, Senior Systems Engineers focus on designing and implementing complex infrastructure, whereas Systems Administrators handle routine maintenance and user support. The senior role typically requires more advanced certifications and experience, and often involves strategic planning and system architecture.

More about Senior Systems Engineer jobs

What are the most commonly searched types of Systems Engineer jobs in Rochester, NH?

The most popular types of Systems Engineer jobs in Rochester, NH are:

What are popular job titles related to Senior Systems Engineer jobs in Rochester, NH?

For Senior Systems Engineer jobs in Rochester, NH, the most frequently searched job titles are:

What cities near Rochester, NH are hiring for Senior Systems Engineer jobs?

Cities near Rochester, NH with the most Senior Systems Engineer job openings:

Senior Systems Engineer jobs near you
Infographic showing various Senior Systems Engineer job openings in Rochester, NH as of August 2026, with employment types broken down into 83% Full Time, 13% Part Time, 3% Contract, and 1% Nights. Highlights an 86% Physical, 2% Hybrid, and 12% Remote job distribution, with an average salary of $122,345 per year, or $58.8 per hour.

Systems Engineer, Level 3

Lonza

Portsmouth, NH • On-site

Full-time

Medical, Dental, Vision, Retirement

Re-posted 6 days ago

Lonza rating

8.3

Company rating: 8.3 out of 10

Based on 42 frontline employees who took The Breakroom Quiz

25th of 86 rated pharmaceutical

Job description

System Engineer, Level 3
Location: On-site, Portsmouth, NH. Relocation assistance is available for eligible candidates and their families, if needed.
The Systems Engineer will support ongoing Lonza operations through technical assistance as it relates to computerized systems infrastructure for process automation and QC laboratory systems. This person provides a technical resource to operations customers to ensure that systems are designed and operating to meet production needs.
What you will get:
  • An agile career and dynamic working culture.
  • An inclusive and ethical workplace.
  • Competitive salary and performance-based bonuses
  • 401(k) matching plan.
  • Competitive compensation programs that reward high performance.
  • Comprehensive medical, dental, and vision insurance.

Access to our full list of global benefits: https://www.lonza.com/careers/benefits
What you will do:
  • Administer, monitor, and maintain manufacturing execution systems using Emerson Syncade (or equivalent such as Lonza MODA-ES and RockwellPharma Suite) including application servers, web servers, system interfaces, and other integration points.
  • Support batch record execution, electronic work instructions, and material tracking performance within the MES environments.
  • Coordinate MES patching, upgrades, and system validation testing in accordance with change control procedures.
  • Serve as primary technical point of contact for MES-related system incidents, working closely with production, automation engineering teams, and quality to minimize downtime.
  • Support connectivity between MES, DCS, analytical systems, and PLC platforms (Rockwell/Allen, Siemens) via Kepware, OPC Router, or similar middleware.
  • Troubleshoot data flow, perform ad-hoc queries, manage vendor tickets, lead root cause analysis, and provide 24/7 on-call support.
  • Maintain IT and regulatory compliance, update system documentation, and collaborate on site and global projects.

What we are looking for:
  • Bachelor's degree in Computer Science, Information Technology, a related field, or equivalent practical experience with minimum of 3-5 years of experience in systems administration or network engineering.
  • 3+ years of experience administering Windows Server environments, Active Directory, and SQL Server.
  • A strong proficiency in Microsoft Windows Server administration, including hands-on experience with Active Directory and related Windows services and an understanding of virtualization technologies such as VMware or HyperV.
  • Experience administering platforms like Emerson Syncade and data historians like OSIsoft PI.
  • Proficiency in PowerShell and Visual Basic for automation and troubleshooting. Knowledge of Kepware, FactoryTalk, OPC Router, and DCOM/OPC configurations.
  • Background in validated GxP environments, change control, and relevant technical certifications.

About Lonza
At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone's ideas, big or small, have the potential to improve millions of lives, and that's the kind of work we want you to be part of.
Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you're ready to help turn our customers' breakthrough ideas into viable therapies, we look forward to welcoming you on board.
Ready to shape the future of life sciences? Apply now.

What Lonza employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

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About Lonza

Sourced by ZipRecruiter

Industry

Biotechnology research and development and pharmaceutical and medicine manufacturing

Company size

10,000+ Employees

Headquarters location

Bern, KS, US

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