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Senior Statistician Jobs in Chicago, IL (NOW HIRING)

Chicago Public Schools

Senior Data Strategist

Chicago, IL · On-site

$89.70K - $110.30K/yr

Senior Data Strategist Chicago Public Schools (CPS) is a district on the rise, serving over 320,000 students in 500+ schools and employing over 44,000 people, most of them teachers. CPS has set ...

Epsilon

Senior Digital Solutions Consultant

Chicago, IL · On-site

$82.10K - $163.20K/yr

We are looking for a Senior Digital Solutions Consultant to join our Digital Strategy team. This role is not channel specific, though work may frequently involve CRM, lifecycle marketing, audience ...

cap

Senior SAS Programmer

Winnetka, IL · Remote

$87K - $111K/yr

Brief Description The Senior SAS Programmer in the Biostatistics Department is responsible for ... Having the experience and expertise to handle complex research or development statistical ...

TENDO

Senior Data Scientist

Chicago, IL · On-site

$110.50K - $149.50K/yr

Senior Data Scientist The Senior Data Scientist will support Tendo analytics projects focused on ... Develop analytic data sets and use statistical software to analyze data sets as requested. * Use ...

Cedent Life Talent

Sr. Data Scientist

Chicago, IL · On-site

... senior clients * Explain complex modeling approaches in simple terms and develop compelling ... Master's degree in statistics, economics, operations research, engineering, or related field * 6+ ...

1872 Consulting

Senior Financial Data Analyst

Chicago, IL · Hybrid

$88.10K - $109.70K/yr

Senior Financial Data Analyst Chicago, IL (hybrid WFH 2 days, onsite 3 days in Willis Tower in the ... statistical and financial techniques to create and manipulate complex datasets to identify trends ...

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$24.7K

$102.1K

$172.2K

How much do senior statistician jobs pay per year?

As of May 28, 2026, the average yearly pay for senior statistician in Chicago, IL is $102,073.00, according to ZipRecruiter salary data. Most workers in this role earn between $89,700.00 and $110,300.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Statistician, and why are they important?

To thrive as a Senior Statistician, you need advanced knowledge of statistical theory, data analysis, and experimental design, typically supported by a master’s or doctoral degree in statistics or a related field. Expertise with statistical software such as R, SAS, Python, and proficiency in data management systems are commonly required, along with relevant certifications or training. Strong problem-solving skills, attention to detail, and the ability to communicate complex findings clearly set top candidates apart. These abilities are crucial for delivering accurate insights that inform high-stakes business or scientific decisions.

How do Senior Statisticians typically collaborate with cross-functional teams within an organization?

Senior Statisticians frequently work alongside professionals from diverse backgrounds, such as data scientists, subject matter experts, and business analysts. They play a key role in translating complex statistical findings into actionable insights for non-technical stakeholders. Collaboration often involves participating in project meetings, advising on study design, and ensuring that statistical methods align with project objectives. Effective communication and adaptability are crucial, as Senior Statisticians must tailor their approach to support various departmental needs and drive data-informed decision-making.

What does a Senior Statistician do?

A Senior Statistician is responsible for designing, analyzing, and interpreting complex data to help organizations make informed decisions. They often lead statistical projects, develop methodologies, and ensure the accuracy and reliability of data analysis. Senior Statisticians may also mentor junior staff, collaborate with cross-functional teams, and communicate findings to both technical and non-technical audiences. Their work is crucial in fields such as healthcare, finance, government, and research. They use advanced statistical software and techniques to solve real-world problems and drive strategic initiatives.

Is AI replacing statisticians?

AI is transforming the role of senior statisticians by automating data analysis tasks and enhancing predictive modeling, but it does not replace the need for expert interpretation, domain knowledge, and critical thinking. Statisticians are increasingly using AI tools and programming languages like R or Python to improve efficiency and accuracy. Human oversight remains essential for designing studies, validating models, and making informed decisions based on complex data.

What is the difference between Senior Statistician vs Data Analyst?

AspectSenior StatisticianData Analyst
Required CredentialsMaster's or PhD in Statistics, Mathematics, or related fieldBachelor's or Master's in Statistics, Data Science, or related field
Work EnvironmentResearch-focused, often in healthcare, finance, or government sectorsBusiness, marketing, or technology sectors, often in corporate settings
Employer & Industry UsageUsed in industries requiring advanced statistical modeling and analysisCommon in industries focusing on data reporting and visualization

While both roles analyze data, a Senior Statistician typically handles complex statistical modeling and research, often requiring advanced degrees. Data Analysts focus on interpreting data for business insights, using tools like Excel and SQL. The Senior Statistician's role is more research-oriented, whereas Data Analysts are more involved in data reporting and visualization for decision-making.

What are the most commonly searched types of Statistician jobs in Chicago, IL? The most popular types of Statistician jobs in Chicago, IL are:
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What cities near Chicago, IL are hiring for Senior Statistician jobs? Cities near Chicago, IL with the most Senior Statistician job openings:
Senior Statistician jobs near you
Infographic showing various Senior Statistician job openings in Chicago, IL as of May 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $102,073 per year, or $49.1 per hour.

Team Lead, Statistical Programming, Oncology (Director)

Astellas Pharma, Inc.

Northbrook, IL • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 15 days ago

Job description

About Astellas
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.
Are you driven to make a real difference in the lives of patients?
We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.
Purpose & Scope
As a senior statistician, data scientist or clinical programmer, the position has a dual purpose: manage 4+ direct reports and have a major influence on the leadership and technical capabilities of the department.
The position can act as Global Statistical lead (GSTATL), Global Programmer Lead (GPROGL), Real World Data Scientist lead (RWDSL), Lead Product Statistician (LPS), Statistical Biomarker Lead (SBL) or as a Regional/site Head.
With no or minimal experience as people manager and an extensive knowledge of the scientific and regulatory area of responsibility and experience in multiple indications; the position is expected to ask critical scientific questions, challenge hypotheses, designs and results interpretation.
The position is responsible for the optimal development and assignments of reports (all individual contributors; Statistical Science Lead, Statistician, Statistical programming Lead, Programmer and RWD scientist) to Astellas asset teams, study teams or deliverables teams (e.g. IEGP, EDAP) for the assigned projects.
The position supports Senior management with decision making at the asset and portfolio level with an impact within and outside of the organization. The position works independently and involves the right level of participants as needed effectively engaged as a matrix team member in M&D.
This position represents Astellas on statistical matters related to clinical data, RWD, Biomarkers PROs, PK/PD analysis or methodology at meetings with regulatory authorities, key opinion leaders and HTAs
Role and Responsibilities
The position is accountable for multiple projects, challenging and assessing the asset strategy and ensuring the statistical/scientific soundness of all input and deliverables for the assigned projects. The position works on the most complex and critical projects from pre-Candidate Nomination (CN) till life cycle management impacting CN, Proof of Concept, approval and post submission strategies.
  • Advises asset teams on challenging statistical/epidemiological design, analysis and decision-making issues for interventional and non-interventional studies.
  • How RWD and Clinical Trial post hoc analyses can support drug development, Pricing submissions and the Growth strategy in general.
  • How omics and biomarkers can support drug development and the BOLD objectives
  • How programming support will be executed for all stakeholders' needs globally. Performs/supervises modeling and simulations, leverages external experts to provide input to clinical development issues.
  • Provides oversight on statistical/scientific/programming matters for meetings with regulatory authorities, HTAs, key opinion leaders and similar experts
  • Reviews key project level documents
  • Participates in due diligence activities, external initiatives or working groups.
  • Presents and defends complex solutions to governance committees (KACHI, PRC, MA-C, EC), key stakeholders, or regulatory bodies in a compelling and impactful way
  • Stays at the cutting edge of methodology development in statistics, epidemiology, regulatory and HTA guidelines, and industry trends in drug development, particularly with respect to the Primary Focus of interest, and signals relevant developments in a timely manner for the company.
  • Ensures efficient and innovative ways of programming are selected for each deliverable
  • Researches, creates, validates, implements and teaches complex methodologies ensuring the department stays at the forefront of innovational drug development

People Management
  • Supervision (first line manager) of 4+ direct reports
  • Assist with recruitment, development / career management and retention of staff
  • Oversees adherence to timelines, standards, processes for work assigned to their members of staff
  • Responsible for compliance of direct reports with Astellas policies and procedures

Personal development / Collaboration
  • Challenges and influences peers and senior managers inside and outside of Quantitative Sciences and Evidence Generation (QSEG) on best practice in their area of competence
  • As a leader, member of external industry or professional organizations, develops and maintains relationships with peers and key leaders. Actively participates in professional association activities to support the branding of Astellas
  • Understands Astellas' priorities, uses position to advance Astellas' mission through high quality statistical programming work - ensures programming team stays current with changes in regulatory requirements globally
  • Contributes in ensuring that Astellas is at the forefront of recruitment, training, professional development and retention of statistical programming personnel.
  • Partners with SRS LT to set short- and long-term strategic direction for programming function.
  • Partners with programming team in other Astellas sites to ensure global consistency, global efficient resource utilization and development.

Required Qualifications
  • Bachelor's or master's in statistics, mathematics, or related field
  • 12+ years (15+ years for Bachelor) of experience of relevant programming experience in the pharmaceutical industry and working with vendors
  • 8+ years' experience as a lead programmer working on global clinical studies and projects or global process and system initiatives
  • 5+ years' experience in mentoring/leading statistical programmers
  • Prior working experience with Oncology
  • Prior experiencing leading a team

Location and Working Environment
This position is based in Northbrook, Illinois. Remote work from anywhere in the US is available.
At Astellas we recognize the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimize the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas' Responsible Flexibility Guidelines.
What awaits you at Astellas?
  • Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
  • Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
  • Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
  • A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.

Our Organizational Values and Behaviors
Values: Innovation, Integrity and Impact sit at the heart of what we do.
Behaviors: We come together as 'One Astellas', working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.
Salary Range
$170,450 - $243,500 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations)
Benefits:
  • Medical, Dental and Vision Insurance
  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
  • 401(k) match and annual company contribution
  • Company paid life insurance
  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
  • Long Term Incentive Plan for eligible positions
  • Company fleet vehicle for eligible positions
  • Referral bonus program

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