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Senior Statistical Programmer Jobs in Frederick, MD

Sr AI/ML Engineer

Hagerstown, MD

$103K - $142K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

The Senior AI/ML Engineer is a highly skilled and experienced professional responsible for leading ... Bachelor's degree in computer science, mathematics, applied statistics, various engineering ...

Sr. Microbiologist

Leesburg, VA · On-site

$80K - $90K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Interpret sampling and monitoring data using statistical and analytical techniques to determine ... Work cross-functionally with Manufacturing Engineering, R&D, Operations, and Regulatory Affairs to ...

Senior Manager, Forecasting

Gaithersburg, MD · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

The Senior Manager seamlessly collaborates with Insights and Analytics colleagues to deliver data ... Engineering, Data Science, Statistics, Math, Economics,Computer Science,Operations Research) * 2 ...

Senior Manager, Forecasting

Gaithersburg, MD · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

The Senior Manager seamlessly collaborates with Insights and Analytics colleagues to deliver data ... Engineering, Data Science, Statistics, Math, Economics,Computer Science,Operations Research) * 2 ...

Staff Platform Engineer

Gaithersburg, MD · On-site +1

$185K - $220K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

We are hiring a senior engineer to own bfARENAS end-to-end and lead its evolution into a self-serve ... Real statistical literacy. Comfort with ranking and pairwise comparison models, bootstrap methods ...

Staff Platform Engineer

Gaithersburg, MD · On-site

$185K - $220K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

We are hiring a senior engineer to own bfARENAS end-to-end and lead its evolution into a self-serve ... Real statistical literacy. Comfort with ranking and pairwise comparison models, bootstrap methods ...

Senior Manager, Forecasting

Gaithersburg, MD · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

The Forecasting Senior Manager, Oncology leads the US forecasting process for one of the key brands ... g., Engineering, Data Science, Statistics, Math, Economics, Computer Science, Operations Research ...

Senior Manager, Forecasting

Gaithersburg, MD · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

The Forecasting Senior Manager, Oncology leads the US forecasting process for one of the key brands ... g., Engineering, Data Science, Statistics, Math, Economics, Computer Science, Operations Research ...

Senior Manager, IO Forecasting

Gaithersburg, MD · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Senior Manager, IO Forecasting leads the US forecasting process for a key tumor type within the US ... g., Engineering, Data Science, Statistics, Math, Economics, Computer Science, Operations Research ...

Senior Manager, IO Forecasting

Gaithersburg, MD · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Senior Manager, IO Forecasting leads the US forecasting process for a key tumor type within the US ... g., Engineering, Data Science, Statistics, Math, Economics, Computer Science, Operations Research ...

Senior Manager, IO Forecasting

Gaithersburg, MD · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Senior Manager, IO Forecasting leads the US forecasting process for a key tumor type within the US ... g., Engineering, Data Science, Statistics, Math, Economics, Computer Science, Operations Research ...

Showing results 41-60

Senior Statistical Programmer information

See Frederick, MD salary details

$82K

$127.6K

$166.5K

How much do senior statistical programmer jobs pay per year?

As of Aug 19, 2026, the average yearly pay for senior statistical programmer in Frederick, MD is $127,558.00, according to ZipRecruiter salary data. Most workers in this role earn between $106,400.00 and $147,200.00 per year, depending on experience, location, and employer.

What is a senior statistical programmer?

A Senior Statistical Programmer is responsible for developing, testing, and validating statistical programs used for clinical trial data analysis. They work primarily with statistical software like SAS to generate tables, listings, and figures (TLFs) for regulatory submissions and research studies. This role requires strong programming skills, knowledge of statistical methodologies, and an understanding of clinical trial processes. Senior Statistical Programmers also collaborate with statisticians, data managers, and regulatory teams to ensure data integrity and compliance with industry standards.

What are the typical responsibilities and team dynamics for a senior statistical programmer?

As a Senior Statistical Programmer, you will typically be responsible for designing, developing, and validating statistical programs for clinical trial data analysis and reporting. You’ll work closely with biostatisticians, data managers, and clinical project teams to ensure data quality and regulatory compliance, often contributing to the creation of submission datasets and study reports. The role usually involves both independent work and active collaboration, with seasoned programmers frequently mentoring junior staff and participating in process improvement initiatives. This team-oriented structure offers exposure to a variety of projects and stakeholders, making it a dynamic environment ideal for those who enjoy both analytical tasks and cross-functional teamwork.

What are the key skills and qualifications needed to thrive as a senior statistical programmer, and why are they important?

To thrive as a Senior Statistical Programmer, a strong background in statistical analysis, programming (often in SAS and R), and a relevant degree such as in statistics, mathematics, or computer science is essential. Experience with regulatory submission standards (like CDISC SDTM/ADaM), clinical trial software, and certifications such as SAS Certified Advanced Programmer are highly valued. Outstanding attention to detail, problem-solving abilities, and effective communication skills help individuals excel in this collaborative and deadline-driven role. These skills are crucial for ensuring accurate data analysis, regulatory compliance, and successful teamwork in high-stakes research environments.

What are the most commonly searched types of Statistical Programmer jobs in Frederick, MD?

The most popular types of Statistical Programmer jobs in Frederick, MD are:

What are popular job titles related to Senior Statistical Programmer jobs in Frederick, MD?

For Senior Statistical Programmer jobs in Frederick, MD, the most frequently searched job titles are:

What job categories do people searching Senior Statistical Programmer jobs in Frederick, MD look for?

The top searched job categories for Senior Statistical Programmer jobs in Frederick, MD are:

What cities near Frederick, MD are hiring for Senior Statistical Programmer jobs?

Cities near Frederick, MD with the most Senior Statistical Programmer job openings:

Infographic showing various Senior Statistical Programmer job openings in Frederick, MD as of August 2026, with employment types broken down into 57% Full Time, and 43% Contract. Highlights an 100% In-person job distribution, with an average salary of $127,558 per year, or $61.3 per hour.

$103K - $142K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 14 days ago


Sierra Nevada Corporation rating

8.7

Company rating: 8.7 out of 10

Based on 29 frontline employees who took The Breakroom Quiz

17th of 72 rated aerospace companies


Job description

The Senior AI/ML Engineer is a highly skilled and experienced professional responsible for leading the development of complex AI/ML systems, driving innovation, and mentoring team members to deliver impactful solutions. In this role, you will oversee the design, implementation, and deployment of scalable AI/ML models for mission-critical aerospace and defense applications. You will also act as a technical leader, providing strategic guidance on AI/ML initiatives, ensuring compliance with regulatory standards, and collaborating with stakeholders to meet organizational objectives. This position demands advanced technical expertise and the ability to manage high-impact projects in a fast-paced environment.As SNC's corporate team, we provide the company and its business areas with strategic direction and business support spanning executive management, finance and accounting, operations, human resources, legal, IT, information security, facilities, marketing, and communications.

Responsibilities:

  • Exploration & Innovation:
    • Conduct continuous discovery and hypothesis-driven experimentation, rapidly developing prototypes to assess feasibility and potential impact.
    • Partner with business stakeholders to translate non-technical requirements into actionable AI/ML exploration paths.
  • RAG-Focused AI/ML Development:
    • Develop and prototype RAG-based architectures, including embedding pipelines, retrieval strategies, and transformer-based generative components.
    • Explore and validate new approaches for retrieval, indexing, and multimodal document understanding.
    • Apply validation, safety, and explainability practices in support of aerospace/defense requirements.
  • MPC & Real-Time Decisioning Exploration:
    • Design and prototype MPC-aligned models incorporating predictive modeling, optimization, and reinforcement-learning-based control.
    • Develop signal processing, perception, and planning pipelines supporting MPC control loops.
    • Use GPU acceleration, simulation environments, and HPC resources to support MPC experimentation.
  • Advanced AI/ML Modeling & Technical Leadership:
    • Architect, train, and optimize advanced models including transformers, GANs, RL agents, and real-time systems.
    • Provide technical leadership, mentor engineers, and guide cross-functional teams.
  • Safety, Validation & Integration Support:
    • Develop validation and testing frameworks ensuring compliance with safety and reliability standards.
    • Support integration teams with prototypes, documentation, and technical insights as required.

Qualifications You Must Have:

  • Bachelor's degree in computer science, mathematics, applied statistics, various engineering disciplines, or related STEM discipline
  • 10+ years of experience in a related field.
  • Relevant experience can be considered as a substitute for the required educational qualifications. In the absence of a degree, a minimum of 12 years of related experience is required.
  • Higher level relevant degree may substitute for experience.
  • Advanced skills in machine learning frameworks (TensorFlow, PyTorch) and modern AI/ML techniques, including supervised, unsupervised, and reinforcement learning (e.g., PPO, Actor/Critic). Demonstrated ability to design and optimize generative AI models (e.g., transformers) and neural networks for complex applications.
  • Extensive experience architecting, deploying, and optimizing AI/ML systems, including ANNs, CNNs, and RNNs, in large-scale or mission-critical environments. Led efforts to improve model performance and reliability in production settings.
  • Strong proficiency in programming languages such as Python, C++, C# or Java, with experience in building scalable AI/ML systems.
  • Demonstrated experience leading teams or projects, including mentoring junior staff.
  • Proven track record of deploying AI/ML models in production environments and optimizing them for real-world use cases.
  • Knowledge of regulatory and cybersecurity requirements for AI/ML systems in aerospace and defense applications.
  • Experience designing and optimizing generative AI models including transformers and GANs.
  • Experience building or integrating transformer-based models for retrieval-augmented or hybrid reasoning systems.
  • Proficiency designing embedding, retrieval, or indexing pipelines for large, multi-source datasets.
  • Familiarity with explainable AI (XAI) techniques for safety-critical environments.
  • Hands-on experience with reinforcement learning and real-time systems applicable to MPC.

Qualifications We Prefer:

  • Master's degree + additional years experience, or Ph.D. in Artificial Intelligence, Machine Learning, or a related field.
  • Experience with hardware acceleration technologies (e.g., CUDA, TensorRT) and high-performance computing systems.
  • Background in autonomous systems, robotics, or sensor fusion.
  • Familiarity with Agile/DevOps methodologies for software development.
  • Certifications in AI/ML or related fields, such as AWS Certified Machine Learning Specialty or Google Professional Machine Learning Engineer.
  • Deep understanding and practical application of Agile/DevOps in large-scale AI/ML projects.
  • Demonstrated experience with reinforcement learning and generative AI models in production or research settings.
  • Advanced proficiency in GPU programming, parallel/distributed computing, and optimizing ML workloads for performance.
  • Expertise in designing and implementing complex ML pipelines, including clustering, dimensionality reduction, generative modeling, and reinforcement learning, aligned to mission objectives and HMI systems.
  • Skilled in analyzing massive, multi-source datasets and delivering end-to-end autonomy software solutions, from requirements to deployment and maintenance.
  • Working knowledge of hardware acceleration technologies (CUDA, TensorRT), edge AI deployments, and explainable AI (XAI) methods.
  • Exposure to or interest in quantum computing for ML applications.

Essential Functions:


  • Contribute to AI/ML innovation and prototyping projects from exploration through technical feasibility assessment.
  • Support cross-functional engineering teams and integration efforts as needed.
  • Travel occasionally (10-20%) to customer sites, test facilities, or conferences.
  • Work in a hybrid office environment, balancing hands-on research with technical leadership.
  • Ensure compliance with safety, regulatory, and cybersecurity standards for AI/ML systems.

This posting will be open for application for a minimum of 5 days and may be extended based on business needs.

Estimated Starting Salary Range: $143,487.14 - $197,294.82. Compensation varies depending on a wide array of factors, such as candidates' key skills, relevant work experience, and education/training/certifications. The disclosed range estimate may be adjusted for any applicable geographic differential associated with the location at which the position may be filled.

SNC offers annual incentive pay based upon performance that is commensurate with the level of the position.

SNC offers a generous benefit package, including medical, dental, and vision plans, 401(k) with 150% match up to 6%, life insurance, 3 weeks paid time off, tuition reimbursement, and more.

IMPORTANT NOTICE:

This position requires the ability to obtain and maintain a Secret U.S. Security Clearance. U.S. Citizenship status is required as this position needs an active U.S. Security Clearance for employment. Non-U.S. citizens may not be eligible to obtain a security clearance. The Department of Defense Consolidated Adjudications Facility (DoD CAF), a federal government agency, handles the adjudicative aspects of the security clearance eligibility process for industry applicants. Adjudicative factors which affect the outcome of the eligibility determination include, but are not limited to, allegiance to the U.S., foreign influence, foreign preference, criminal conduct, security violations and illegal drug use.

Learn more about the background check process for Security Clearances.

SNC is a global leader in aerospace and national security committed to moving the American Dream forward. We're known and respected for our mission and execution focus, agility, and disruptive and rapid innovation. We provide leading edge technologies and transformative solutions that support our nation's most critical security needs. If you are mission-focused, thrive in collaborative environments, and want to make our country stronger with state-of-the-art technologies that safeguard freedom, join our team!

SNC is an Equal Opportunity Employer committed to an environment free of discrimination. Employment decisions are made based on merit without regard to race, color, age, religion, sex, national origin, disability, status as a protected veteran or other characteristics protected by law.


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