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Senior Statistical Programmer Jobs in Colmar, PA

Pwc

CTIO - AI Engineer- Senior Manager

Philadelphia, PA

$91K - $321K/yr

... Engineer- Senior Manager, you will play a pivotal role in transforming raw data into actionable ... In this role, you will engage in exploratory and descriptive analysis, statistical modeling, and ...

TheMasonGroup

Senior Mechanical Engineer

Richboro, PA

$99K - $131K/yr

Senior Mechanical Engineer (Manufacturing) We are seeking a growth-minded, results-driven Senior ... Exposure to quality control processes, including statistical process control (SPC), lean ...

Techvilla Solutions

Senior Data Engineer

Furlong, PA · On-site

$104K - $141K/yr

We are seeking a Senior Data Engineer to design, develop, and maintain scalable data pipelines and ... Generate statistical and operational reports and perform program/data validation. * Mentor junior ...

New

Techvilla Solutions

Senior Data Engineer

Merion Station, PA

$101K - $137K/yr

We are seeking a Senior Data Engineer to design, develop, and maintain scalable data pipelines and ... Generate statistical and operational reports and perform program/data validation. * Mentor junior ...

New

Techvilla Solutions

Senior Data Engineer

Dresher, PA

$102K - $139K/yr

We are seeking a Senior Data Engineer to design, develop, and maintain scalable data pipelines and ... Generate statistical and operational reports and perform program/data validation. * Mentor junior ...

New

Techvilla Solutions

Senior Data Engineer

Spring House, PA

$101K - $137K/yr

We are seeking a Senior Data Engineer to design, develop, and maintain scalable data pipelines and ... Generate statistical and operational reports and perform program/data validation. * Mentor junior ...

New

Techvilla Solutions

Senior Data Engineer

Limerick, PA

$101K - $138K/yr

We are seeking a Senior Data Engineer to design, develop, and maintain scalable data pipelines and ... Generate statistical and operational reports and perform program/data validation. * Mentor junior ...

New

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All JobsStatistical Programmer JobsSenior Statistical Programmer JobsSenior Statistical Programmer Jobs in Colmar, PA

Senior Statistical Programmer information

See Colmar, PA salary details

$81.6K

$126.9K

$165.7K

How much do senior statistical programmer jobs pay per year?

As of Sep 4, 2026, the average yearly pay for senior statistical programmer in Colmar, PA is $126,947.00, according to ZipRecruiter salary data. Most workers in this role earn between $105,900.00 and $146,400.00 per year, depending on experience, location, and employer.

What is a senior statistical programmer?

A Senior Statistical Programmer is responsible for developing, testing, and validating statistical programs used for clinical trial data analysis. They work primarily with statistical software like SAS to generate tables, listings, and figures (TLFs) for regulatory submissions and research studies. This role requires strong programming skills, knowledge of statistical methodologies, and an understanding of clinical trial processes. Senior Statistical Programmers also collaborate with statisticians, data managers, and regulatory teams to ensure data integrity and compliance with industry standards.

What are the typical responsibilities and team dynamics for a senior statistical programmer?

As a Senior Statistical Programmer, you will typically be responsible for designing, developing, and validating statistical programs for clinical trial data analysis and reporting. You’ll work closely with biostatisticians, data managers, and clinical project teams to ensure data quality and regulatory compliance, often contributing to the creation of submission datasets and study reports. The role usually involves both independent work and active collaboration, with seasoned programmers frequently mentoring junior staff and participating in process improvement initiatives. This team-oriented structure offers exposure to a variety of projects and stakeholders, making it a dynamic environment ideal for those who enjoy both analytical tasks and cross-functional teamwork.

What are the key skills and qualifications needed to thrive as a senior statistical programmer, and why are they important?

To thrive as a Senior Statistical Programmer, a strong background in statistical analysis, programming (often in SAS and R), and a relevant degree such as in statistics, mathematics, or computer science is essential. Experience with regulatory submission standards (like CDISC SDTM/ADaM), clinical trial software, and certifications such as SAS Certified Advanced Programmer are highly valued. Outstanding attention to detail, problem-solving abilities, and effective communication skills help individuals excel in this collaborative and deadline-driven role. These skills are crucial for ensuring accurate data analysis, regulatory compliance, and successful teamwork in high-stakes research environments.

What cities near Colmar, PA are hiring for Senior Statistical Programmer jobs?

Cities near Colmar, PA with the most Senior Statistical Programmer job openings:

Senior Statistical Programmer jobs near you
Infographic showing various Senior Statistical Programmer job openings in Colmar, PA as of August 2026, with employment types broken down into 1% Internship, 82% Full Time, 14% Part Time, and 3% Contract. Highlights an 79% Physical, 3% Hybrid, and 18% Remote job distribution, with an average salary of $126,947 per year, or $61 per hour.

Model Validator, Senior Specialist

Vanguard Group, Inc.

Malvern, PA • On-site

$85K - $105K/yr

Full-time

Posted 5 days ago

Vanguard rating

8.7

Company rating: 8.7 out of 10

Based on 64 frontline employees who took The Breakroom Quiz

16th of 154 rated financial services

Job description

The Model Risk Management (MRM) Team, part of Vanguard's second line of defense, is seeking an experienced model risk professional to support independent oversight of AI/ML and generative AI models built and/or used across the enterprise.
Vanguard is a global investment management firm with a mission to give investors the best chance for investment success. Across its businesses and support functions, Vanguard uses AI to drive effectiveness, efficiency, and a range of key business outcomes.
In this role, you will lead the independent validation and challenge of AI models, ensuring they are conceptually sound, well-governed, and fit for purpose. You will work closely with data scientists, quantitative developers, model users, and technology partners, providing credible challenge while maintaining strong, collaborative relationships with the business.
Beyond individual model reviews, you will help drive the evolution of Vanguard's model risk management framework, shaping methodologies, standards, and practices that support consistent, enterprise-wide application of model risk principles.
Core Responsibilities
  • Assess models and systems using generative AI throughout their lifecycle including leading independent validations and assessment of ongoing monitoring, change management, and remediations of model risk findings
  • Provide effective challenge of model assumptions, methodologies, data, testing, implementation, monitoring and limitations, with a focus on material risk drivers
  • Assess compliance with internal AI standards, emerging regulatory requirements, and governance expectations related to AI/ML and generative AI systems, including fairness, explainability, transparency, and human oversight
  • Ensure timely execution of model validation and high-quality validation reports that meet internal standards, and communicate validation findings clearly to technical and non-technical stakeholders
  • Develop, maintain and enhance validation procedures to support a consistent, risk-based approach for independent validation and effective challenge of AI/ML and generative AI systems, including keeping informed of the evolution of technology in generative and agentic AI
  • Contribute to the design and enhancement of model risk management policies, standards, and procedures across the full model lifecycle (inventory, development, validation, approval, and ongoing monitoring)
  • Support the MRM team in advising stakeholders on Model Risk policy and other relevant standards as needed
  • Identify emerging and top risks across the portfolio of AI/ML and generative AI models and surface them to MRM leadership
  • Provide coaching and mentorship to junior team members
  • Participate in special projects and perform other duties as assigned

Qualifications
  • PhD in a quantitative discipline such as Computer Science, Mathematics, Statistics, Physics, Engineering or an equivalent combination of training and experience
  • Minimum of 7 years of relevant experience in model development or model validation
  • Experience developing, testing or validating AI/ML models or systems using generative AI is required
  • Knowledge of programming languages including Python is a requirement
  • Knowledge of technology platforms used for model development and deployment, CI/CD is a requirement
  • Knowledge of generative AI architectures including foundation models, RAG systems, agentic workflows, prompt engineering approaches, and associated risks such as hallucinations, algorithmic bias, and harmful outputs
  • Knowledge of AI/ML modeling including ML algorithms, NLP, deep learning, and evaluation methodologies
  • Exceptional written communication skills are required, including the ability to communicate complex model risks to audiences ranging from technical practitioners to senior executives
  • Experience in the financial services sector is a plus
  • Broad knowledge of risk management at financial institutions preferred
  • Ability to deal effectively with a variety of stakeholder teams
  • Ability to effectively manage multiple and competing priorities
  • Exhibits flexibility and excellent judgment

Special Factors
Sponsorship
Vanguard is offering visa sponsorship for this position.
About Vanguard
At Vanguard, we don't just have a mission-we're on a mission.
To work for the long-term financial wellbeing of our clients. To lead through product and services that transform our clients' lives. To learn and develop our skills as individuals and as a team. From Malvern to Melbourne, our mission drives us forward and inspires us to be our best.
How We Work
Vanguard has implemented a hybrid working model for the majority of our crew members, designed to capture the benefits of enhanced flexibility while enabling in-person learning, collaboration, and connection. We believe our mission-driven and highly collaborative culture is a critical enabler to support long-term client outcomes and enrich the employee experience.

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