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Senior Statistical Programmer Jobs in Brookline, MA

Dyne Tx

Senior Director, Biostatistics

Waltham, MA · On-site

$250 - $290/hr

As a senior statistical leader and cross‑functional partner, this role leads statistical ... Management, Statistical Programming, Translational Medicine, Program Management, and other ...

Massgeneralbrigham

Biostatistician Principal

Boston, MA

$56.59 - $82.31/hr

Job Summary The Chai Laboratory seeks a doctoral-level Senior Computational Scientist to provide ... Qualifications Education Master's Degree Statistics required or Master's Degree Related Field of ...

Mass General Brigham

Biostatistician Principal

Boston, MA · On-site

$56.59 - $82.31/hr

Job Summary The Chai Laboratory seeks a doctoral-level Senior Computational Scientist to provide ... Qualifications Education Master's Degree Statistics required or Master's Degree Related Field of ...

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Senior Statistical Programmer information

See Brookline, MA salary details

$89.3K

$138.8K

$181.2K

How much do senior statistical programmer jobs pay per year?

As of Aug 23, 2026, the average yearly pay for senior statistical programmer in Brookline, MA is $138,803.00, according to ZipRecruiter salary data. Most workers in this role earn between $115,800.00 and $160,100.00 per year, depending on experience, location, and employer.

What is a senior statistical programmer?

A Senior Statistical Programmer is responsible for developing, testing, and validating statistical programs used for clinical trial data analysis. They work primarily with statistical software like SAS to generate tables, listings, and figures (TLFs) for regulatory submissions and research studies. This role requires strong programming skills, knowledge of statistical methodologies, and an understanding of clinical trial processes. Senior Statistical Programmers also collaborate with statisticians, data managers, and regulatory teams to ensure data integrity and compliance with industry standards.

What are the typical responsibilities and team dynamics for a senior statistical programmer?

As a Senior Statistical Programmer, you will typically be responsible for designing, developing, and validating statistical programs for clinical trial data analysis and reporting. You’ll work closely with biostatisticians, data managers, and clinical project teams to ensure data quality and regulatory compliance, often contributing to the creation of submission datasets and study reports. The role usually involves both independent work and active collaboration, with seasoned programmers frequently mentoring junior staff and participating in process improvement initiatives. This team-oriented structure offers exposure to a variety of projects and stakeholders, making it a dynamic environment ideal for those who enjoy both analytical tasks and cross-functional teamwork.

What are the key skills and qualifications needed to thrive as a senior statistical programmer, and why are they important?

To thrive as a Senior Statistical Programmer, a strong background in statistical analysis, programming (often in SAS and R), and a relevant degree such as in statistics, mathematics, or computer science is essential. Experience with regulatory submission standards (like CDISC SDTM/ADaM), clinical trial software, and certifications such as SAS Certified Advanced Programmer are highly valued. Outstanding attention to detail, problem-solving abilities, and effective communication skills help individuals excel in this collaborative and deadline-driven role. These skills are crucial for ensuring accurate data analysis, regulatory compliance, and successful teamwork in high-stakes research environments.

What are popular job titles related to Senior Statistical Programmer jobs in Brookline, MA?

For Senior Statistical Programmer jobs in Brookline, MA, the most frequently searched job titles are:

What cities near Brookline, MA are hiring for Senior Statistical Programmer jobs?

Cities near Brookline, MA with the most Senior Statistical Programmer job openings:

Senior Statistical Programmer jobs near you
Infographic showing various Senior Statistical Programmer job openings in Brookline, MA as of June 2026, with employment types broken down into 96% Full Time, 2% Part Time, and 2% Contract. Highlights an 84% Physical, 3% Hybrid, and 13% Remote job distribution, with an average salary of $138,803 per year, or $66.7 per hour.

Statistical Programming Contractor (16-Month Contract)

Crispr Therapeutics

South Boston, MA • On-site

$70 - $80/hr

Full-time

Posted 6 days ago

Job description

Job Description:
Company Overview
ounded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world's first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.
Position Summary
The Statistical Programming Contractor will provide technical support for statistical programming activities for assigned clinical studies, FDA submissions, and the development of initiatives.
Responsibilities
  • Design, develop, evaluate, validate and modify computer programs using SAS to analyze and evaluate clinical data.
  • Have thorough knowledge of CDISC theory and implementation guidelines, able to create and validate CDISC standard datasets
  • Program edit checks and produce quality tables, figures and listings in a timely fashion and high quality.
  • Work closely with Clinical Operations, Data Management and Biostatisticians on various clinical projects so that data analysis can be performed in a timely fashion.

Minimum Qualifications
  • Bachelor's Degree in Statistics, Mathematics, and/or Computer Science/IT background. Master's Degree preferred.
  • Minimum 3 years of statistical programming in a pharmaceutical/biotech or CRO setting (depending on level)
  • Strong knowledge in CDISC including SDTM, ADaM, metadata, controlled terminologies, and data flows, as well as in industry standards for electronic submission of data to FDA.
  • Strong hands-on SAS programing skills and working experience for clinical trial reporting for SDTM, ADaM, Table, figure, and Listing.
  • Excellent working knowledge of SAS/BASE, SAS/STAT, SAS/GRAPH and SAS Macro language.
  • Advanced knowledge of GCP/ICH standards, 21 CFR Part 11.

Preferred Qualifications
  • Strong ability to work within cross-functional teams.
  • Excellent interpersonal, organizational, and multi-tasking skills.

Competencies
  • Collaborative - Openness, One Team
  • Undaunted - Fearless, Can-do attitude
  • Results Orientation - Delivering progress toward our mission. Sense of urgency in solving problems.
  • Entrepreneurial Spirit - Proactive. Ownership mindset.

CRISPR Therapeutics believes in fostering a dynamic workplace that balances remote work flexibility with the benefits of in-person interactions. Our employees work at least three days on-site, creating a collaborative work environment, where we cultivate mentorship opportunities, increase cross-functional communication and offer opportunities for our employees to connect. Certain lab based and manufacturing positions are located fully on-site.
Base pay range of $70.00 - $80.00 per hour.
The hourly rate provided is the reasonable estimate for this contract position. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy

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