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Senior Scientist Downstream Process Development Jobs in Illinois

... biology, downstream processing, formulations, and product development teams. * Travel to ... Work alongside data scientists, IT, and engineering to build and maintain a digital system to ...

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Senior Process Development Engineer

Chicago, IL · On-site

$107K - $138K/yr

The Senior Process Development Engineer is responsible for leading complex process research and ... Interpret experimental data and integrate scientific and engineering principles into process ...

Process Development Scientist Location: Rockford, IL 61101 Duration: 12 Months Job Type: Temporary Assignment Work Type: Onsite Shift Timings: Monday to Friday from 08:00 AM to 05:00 PM Summary The ...

Senior Scientist Process Modeling

Chicago, IL · On-site

$94K - $128K/yr

We're looking for an experienced process scientist or engineer with a strong foundation in first ... As a senior individual contributor, you'll lead the development of process models that simulate ...

As a senior individual contributor, you'll lead the development of process models that simulate ... You'll work closely with process engineers, R&D scientists, and our data science team to connect ...

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Senior Scientist Downstream Process Development information

What does a senior scientist in downstream process development do?

A Senior Scientist in Downstream Process Development focuses on developing, optimizing, and scaling up processes to purify biological products such as proteins or antibodies after cell culture (the 'downstream' part of biomanufacturing). They design experiments, analyze data, and work with cross-functional teams to ensure product quality and regulatory compliance. Their role is critical in moving biopharmaceutical products from research to commercial production by ensuring efficient and robust purification processes.

What are the key skills and qualifications needed to thrive as a senior scientist in downstream process development?

To thrive as a Senior Scientist in Downstream Process Development, you need advanced knowledge in bioprocess engineering, protein purification, and process scale-up, typically supported by a Ph.D. or Master’s degree in a relevant field. Expertise with chromatography systems (such as AKTA), analytical instrumentation, and familiarity with regulatory requirements like GMP are essential. Strong problem-solving abilities, leadership, and effective communication skills distinguish top performers in this role. These competencies are crucial for developing robust, scalable processes that meet quality standards and drive successful product development.

What are some common challenges faced by senior scientists in downstream process development, and how can they be addressed?

Senior Scientists in Downstream Process Development often encounter challenges such as optimizing purification processes for novel biologics, scaling up from lab to production scale, and ensuring product consistency and regulatory compliance. Addressing these challenges typically involves close collaboration with cross-functional teams, continuous process optimization, and staying current with industry advancements in chromatography and filtration technologies. Proactive problem-solving, effective communication, and leveraging data analytics are also key strategies for overcoming obstacles in this role.

What are popular job titles related to Senior Scientist Downstream Process Development jobs in Illinois?

For Senior Scientist Downstream Process Development jobs in Illinois, the most frequently searched job titles are:

What job categories do people searching Senior Scientist Downstream Process Development jobs in Illinois look for?

The top searched job categories for Senior Scientist Downstream Process Development jobs in Illinois are:

What cities in Illinois are hiring for Senior Scientist Downstream Process Development jobs?

Cities in Illinois with the most Senior Scientist Downstream Process Development job openings:

Senior Fermentation Scientist

Jobtailor

Libertyville, IL • On-site

$120 - $180/hr

Other

Posted 3 days ago

New


Job description

  • Lead internal upstream process development efforts at the Sumitomo Biorational Company Biorational Research Center by conducting fermentation experiments in laboratory- and pilot-scale bioreactors.
  • Evaluate the performance of microbial strain candidates by analysis and interpretation of fermentation data.
  • Work with a team of fermentation scientists, downstream process engineers, formulations scientists, microbial engineers and analytical chemists to develop sustainable biorational solutions within the expanding field of BioAgriculture.
  • Design and implement upstream processes to optimize strain performance of bacterial and fungal microorganisms to produce microbial products, metabolites and proteins.
  • Mentor junior team members by training safe and proper use of fermentation and analytical equipment required to execute process development and improvement experiments.
  • Provide guidance to research associates and support their professional development.
  • Take primary responsibility for the operation and troubleshooting of pilot scale fermentation equipment.
  • Design scale up and scale down experiments to execute seamless technology transfer between Research and Manufacturing operations.
  • Build strong relationships with supporting research departments and deliver fermentations on time or ahead of schedule to biology, downstream processing, formulations, and product development teams.
  • Travel to manufacturing site to launch new fermentation processes and troubleshoot current commercial processes.
  • Maintain and further develop collaborative relationship with the pilot and production fermentation team at the manufacturing site.
  • Execute sophisticated process development experiments utilizing statistical tools to ensure process robustness.
  • Work alongside data scientists, IT, and engineering to build and maintain a digital system to organize and archive run data and electronic batch records.
  • Maintain and update laboratory data and documents including electronic lab notebook and SOPs.
  • Conduct all work in strict compliance with all applicable safety requirements, containment requirements, standards operating procedures and/or guidelines while maintaining a clean and orderly workspace.
  • Work both independently and with interdisciplinary research teams while maintaining a positive and collaborative environment.
Requirements
  • Expertise in culturing microorganisms, including filamentous fungi, to increase metabolite productivity using aseptic techniques
  • Hands‑on experience using lab‑scale or pilot‑scale SIP bioreactor systems for microbial cultivations and metabolite production, particularly with non‑model bacterial and fungal organisms
  • Experience training junior scientists in the use of fermentation equipment and execution of process development experiments
  • High degree of competency in the Microsoft Office 365 suite and statistical analysis software
  • Strong communication, presentation, and listening skills in cross‑functional teams
  • Willingness to foster a culture of diversity and inclusion
  • Able to lift up to 25 lbs
  • Degree in Fermentation Science, Chemical/Biochemical/Biosystems Engineering, or closely related field with industrial fermentation experience (5 years with PhD, 8 years with MS, 12+ years with BS).
Core Competencies

Demonstrates expertise in upstream process development and fermentation science, with a strong focus on optimizing microbial strain performance and mentoring junior scientists. Proficient in utilizing statistical tools for process robustness and maintaining compliance with safety and operational standards.

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