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Senior Scientist Downstream Process Development Jobs in Morris, IL

Bioinformatics Management

Campus, IL · Hybrid

$110K - $122K/yr

A senior scientific, clinical informatics, and team-leadership role. It serves as the primary ... Engineering Development: Full-stack software engineering, data persistence, and application ...

Bioinformatics Management

Campus, IL · Hybrid

$110K - $122K/yr

A senior scientific, clinical informatics, and team-leadership role. It serves as the primary ... Engineering Development: Full-stack software engineering, data persistence, and application ...

Bioinformatics Management

Campus, IL · Hybrid

$110K - $122K/yr

A senior scientific, clinical informatics, and team-leadership role. It serves as the primary ... Engineering Development: Full-stack software engineering, data persistence, and application ...

Position Summary The Junior Process Engineer supports process development, optimization, and ... Working under the guidance of senior process engineers, this role assists with production ramp-up ...

Position Summary The Junior Process Engineer supports process development, optimization, and ... Working under the guidance of senior process engineers, this role assists with production ramp-up ...

Lab Technician

Campus, IL · On-site

$18.50 - $24.50/hr

... downstream processing. 6. Process tumor and immune tissues for cellular and molecular assays. 7. ... scientific and professional development. Work Environment and Level of Frequency that may be ...

Lab Technician

Campus, IL

$18.50 - $24.50/hr

... downstream processing. 6. Process tumor and immune tissues for cellular and molecular assays. 7. ... scientific and professional development. Work Environment and Level of Frequency that may be ...

Lab Technician

Campus, IL · On-site

$18.50 - $24.50/hr

... downstream processing. 6. Process tumor and immune tissues for cellular and molecular assays. 7. ... scientific and professional development. Work Environment and Level of Frequency that may be ...

Senior Account Manager

Joliet, IL · On-site

$135.40 - $203/hr

The ability to make an impact with a company that is passionate about your career development ... Targeted accounts are within the Downstream industries * Less than 25% overnight travel required ...

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Senior Scientist Downstream Process Development information

See Morris, IL salary details

$64.5K

$107.2K

$159.5K

How much do senior scientist downstream process development jobs pay per year?

As of Aug 21, 2026, the average yearly pay for senior scientist downstream process development in Morris, IL is $107,216.00, according to ZipRecruiter salary data. Most workers in this role earn between $88,700.00 and $121,200.00 per year, depending on experience, location, and employer.

What does a senior scientist in downstream process development do?

A Senior Scientist in Downstream Process Development focuses on developing, optimizing, and scaling up processes to purify biological products such as proteins or antibodies after cell culture (the 'downstream' part of biomanufacturing). They design experiments, analyze data, and work with cross-functional teams to ensure product quality and regulatory compliance. Their role is critical in moving biopharmaceutical products from research to commercial production by ensuring efficient and robust purification processes.

What are the key skills and qualifications needed to thrive as a senior scientist in downstream process development?

To thrive as a Senior Scientist in Downstream Process Development, you need advanced knowledge in bioprocess engineering, protein purification, and process scale-up, typically supported by a Ph.D. or Master’s degree in a relevant field. Expertise with chromatography systems (such as AKTA), analytical instrumentation, and familiarity with regulatory requirements like GMP are essential. Strong problem-solving abilities, leadership, and effective communication skills distinguish top performers in this role. These competencies are crucial for developing robust, scalable processes that meet quality standards and drive successful product development.

What are some common challenges faced by senior scientists in downstream process development, and how can they be addressed?

Senior Scientists in Downstream Process Development often encounter challenges such as optimizing purification processes for novel biologics, scaling up from lab to production scale, and ensuring product consistency and regulatory compliance. Addressing these challenges typically involves close collaboration with cross-functional teams, continuous process optimization, and staying current with industry advancements in chromatography and filtration technologies. Proactive problem-solving, effective communication, and leveraging data analytics are also key strategies for overcoming obstacles in this role.

Senior Scientist, Computational Materials Solutions

Entegris

Aurora, IL • On-site, Remote

$90K - $123K/yr

Full-time

PTO

Posted 9 days ago


Entegris rating

8.2

Company rating: 8.2 out of 10

Based on 40 frontline employees who took The Breakroom Quiz

87th of 543 rated manufacturers


Job description

Job Title:

Senior Scientist, Computational Materials Solutions

Job Description:

The Role

Entegris is currently seeking aSenior Scientist,Computational Materials Solutionsto join ourDigital Innovation Teamin theTechnology and Innovation organization within our Materials Solutions (MS) business. This position will beremote.

This role focuses on accelerating innovation by combining computational science, machine learning, and domainexpertiseto deepen scientific understanding, guide experimentation, and translate research breakthroughs into scalable technologies for Molecular & Engineering Solutions (MES) business unit. You will translate MES business and technology priorities into actionable computational approaches, including molecular and materials modeling, predictive simulation, statistical and hybrid methods, and scientific data analysis. You will work in close partnership with experimental scientists, engineers, R&D leaders, and cross-functional technology teams to develop solutions that inform materials design, process development, product performance, and next generation technologies. The ideal candidate brings deep quantitative rigor, curiosity-driven problem solving, and the ability to bridge theory, data, and experimentation.

WhatYou'llDo

  • Develop and apply molecular,statisticaland computational, chemistry-informed solutions to investigate material behavior, process mechanisms, and guide materials design.

  • Support MES product and technology development programs through AI/ML, predictive simulations, structure-property analysis, design-of-experiments support, optimization, and reusable computational workflows.

  • Integrate simulation data, experimental results, and domain knowledge to support hypothesis generation, experiment prioritization, and model-based interpretation of R&D results.

  • Perform model calibration, verification, validation, sensitivity analysis, and uncertainty quantification to build scientific confidence in computational recommendations.

  • Translate computational outputs into actionable guidance for MES scientists, engineers, and leaders, including clear communication of assumptions, limitations, uncertainty, and decision implications.

  • Build reusable solution libraries, workflows, documentation, and technical knowledge assets that can be applied across MES priorities and broader Materials Division R&D needs.

  • Communicate modeling assumptions, results, and insights clearly to technical and non-technical stakeholders. Document methods and results in technical reports, internal publications, and knowledge repositories.

WhatWeSeek

  • M.S. or Ph.D. in Chemistry, Materials Science, Physics, Engineering, or related scientific discipline.

  • Strong foundationin computational materials science, computational chemistry, molecular modeling, statistics, scientific computing, and simulation

  • Experience supporting research, experimentation, or early-stage technology development.

  • Ability to connect computational results to physical or chemical mechanisms and translate those results into practical R&D decisions.

  • Working knowledge of model verification, validation, uncertainty quantification, documentation, simulation data management, model reuse, and lifecycle governance.

  • Hands-on experience developing computational, simulation, or data-driven solutions using Python and scientific libraries such as NumPy, pandas, scikit-learn,PyTorch, TensorFlow, or related tools.

  • Strong collaboration, stakeholder-management, and communication skills with the ability to present complex technical work clearly to scientific, engineering, and business audiences.

Preferred Qualifications

  • 1-3 years of experience inmaterials science, chemistry, semiconductor, life sciences, energy, or advanced manufacturing R&D.

  • Demonstrated success combiningexperimental data with modeling and AIto guide discovery or development.

  • Experience with design-of-experiments (DoE), optimization, or Bayesian methods.

  • Familiarity with visualization, notebooks, or technical storytelling for R&D audiences.

  • Publications, patents, or significant internal research contributions.

Why Work at Entegris

Lead. Inspire. Innovate. Define Your Future.

Not everyone who works for a global company shares the same background,experiences and perspectives. Weleveragethe differences of our employees tobringnew ideasto the table. Every employee throughout the company isencouraged to share input on projects and initiatives. Our decision-makingprocess is truly a collaborative effort as we realize there are leaders at everylevel of the organization. We put our values at the core of how weoperateas anorganization - not just whenit'sconvenient, but in a lasting and meaningfulway. We want the time and energy you spend here to have a positive impact onyourlife inside and outside of the office.

WhatWeOffer

Ourtotalrewardspackagegoesaboveandbeyondjustapaycheck.Whetheryou'relooking to build your career, improve your health, or protect your wealth, we offer generous benefits to help you achieve your goals.

  • Compensation: $100,500 - $125,500 per year range with actual pay dependent on candidate overall skills for the role
  • Generous401(K)planwithanimpressiveemployermatch

  • Excellenthealth,dentalandvisioninsurancepackagestofityourneeds

  • Flexibleworkscheduleand11paidholidaysayear

  • Paidtimeoff(PTO)policythatempowersyoutotakethetimeyouneedtorecharge

  • Educationassistancetosupportyourlearningjourney

  • Values-drivenculturewithcolleaguesthatrallyaroundPeople,Accountability,CreativityandExcellence

Entegris does not provide immigration-related sponsorship for this role. Do not apply for this role if you will need Entegris immigration sponsorship (e.g., H1B, TN, STEM OPT, etc.) now or in the future.

At Entegris we are committed toprovidingequal opportunity to all employees and applicants. Our policy is to recruit, hire, train, and reward employees for their individual abilities, achievements, and experience without regard to race, color, religion, sexual orientation, age, national origin, disability, marital or military status.


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