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Senior Remote Net Core Developer Jobs in Boston, MA

Senior Software Engineer

Mansfield, MA · On-site +1

$129K - $171K/yr

Own and evolve core platform modules , from concept through release and support * Influence ... NET- and Python-based systems * Designing and implementing AI-assisted workflows , copilots, or ...

Senior Software Developer

Boston, MA · Remote

$150K - $200K/yr

NET Core (C#), following clean architecture and SOLID principles. * Develop and maintain RESTful ... Fully remote role within the United States * Periodic travel (approximately 10-15 %) for team ...

... remote role for US based candidates, they need to work EST schedule. Salary range: 170-220K USD ... You will own core platform components such as our TypeScript Pulumi codebase, Kubernetes-based ...

Sr. Tax Manager (REMOTE)

Waltham, MA · On-site +1

$134K - $167K/yr

Job Title Sr. Tax Manager (REMOTE) Location(s) Australia Remote, US Remote - CT, US Remote - DC, US ... Revvity is a developer and provider of end-to-end solutions designed to help scientists ...

Senior Donor Advisor

Boston, MA · Remote

$148K - $148K/yr

This is a remote position based Boston, MA area. Position Responsibilities: * Portfolio Management ... Minimum of 7 years of fundraising experience working directly with high-net-worth individuals and ...

Senior Donor Advisor

Waltham, MA · Remote

$149K - $149K/yr

This is a remote position based Boston, MA area. Position Responsibilities: * Portfolio Management ... Minimum of 7 years of fundraising experience working directly with high-net-worth individuals and ...

Senior Donor Advisor

Newton, MA · Remote

$149K - $149K/yr

This is a remote position based Boston, MA area. Position Responsibilities: * Portfolio Management ... Minimum of 7 years of fundraising experience working directly with high-net-worth individuals and ...

Senior Donor Advisor

Andover, MA · Remote

$138K - $138K/yr

This is a remote position based Boston, MA area. Position Responsibilities: * Portfolio Management ... Minimum of 7 years of fundraising experience working directly with high-net-worth individuals and ...

Senior Security Engineer

Boston, MA · On-site +1

$124K - $170K/yr

Senior Security Engineer Remote, United States About this position: We're looking for a Senior ... A core focus of this role is helping Later mature its security capabilities in support of SOC 2 and ...

Senior Data Engineer

Boston, MA · Remote

$115K - $151K/yr

Core Competencies: Knowledge & Application: * Fully proficient in data engineering; applies a ... Fully remote role within the United States * Periodic travel (approximately 5%) for team meetings ...

Manage developer tooling * Ensure compliance with regulatory, compliance and security frameworks ... Candidate can live anywhere in the United States. #LI-MP2 #LI-REMOTE Basic Requirements * 8+ years ...

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Showing results 1-20

Senior Remote Net Core Developer information

See Boston, MA salary details

$39

$65

$85

How much do senior remote net core developer jobs pay per hour?

As of Jul 15, 2026, the average hourly pay for senior remote net core developer in Boston, MA is $65.40, according to ZipRecruiter salary data. Most workers in this role earn between $57.45 and $73.12 per hour, depending on experience, location, and employer.
What are popular job titles related to Senior Remote Net Core Developer jobs in Boston, MA? For Senior Remote Net Core Developer jobs in Boston, MA, the most frequently searched job titles are:
What job categories do people searching Senior Remote Net Core Developer jobs in Boston, MA look for? The top searched job categories for Senior Remote Net Core Developer jobs in Boston, MA are:
Infographic showing various Senior Remote Net Core Developer job openings in Boston, MA as of July 2026, with employment types broken down into 1% As Needed, 78% Full Time, 19% Part Time, and 2% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $136,038 per year, or $65.4 per hour.
Senior Software Engineer

Senior Software Engineer

eClinical Solutions

Mansfield, MA • On-site, Remote

$129K - $171K/yr

Full-time

Re-posted 3 days ago


Job description

About eClinical Solutions
eClinical Solutions is transforming clinical development with elluminate®, our Clinical Data Cloud, helping life sciences organizations unify, analyze, and unlock the value of their data faster than ever before. By combining a modern cloud platform with expert data services, we empower smarter decisions across the clinical trial lifecycle-accelerating innovation that ultimately improves patient outcomes.
Our engineering teams build enterprise-grade, revenue-generating products at the intersection of cloud, data, analytics, and emerging AI technologies. If you're excited about building sophisticated software that makes a real-world impact on healthcare, this is the place to do it.
You will make an impact:
As a Senior Software Engineer, AI Enabled Platforms will be a member of the elluminate product development team. elluminate is a next generation data integration and analytics cloud platform that enables life sciences organizations to optimize the aggregation, standardization, and analysis of their data throughout the clinical development life cycle. You are primarily responsible for the design and development of core modules for the platform and will be involved in all phases of the software development lifecycle such as reviewing functional specifications, design, development, unit testing, code reviews and release management.
This role is ideal for an experienced engineer who enjoys hands-on development, mentoring others, and bringing modern capabilities-including AI-assisted and agentic workflows-into production-grade systems.
Accelerate your skills and career within a fast-growing company while impacting the future of healthcare.
Your day to day:
  • Design, develop, test, and deploy scalable, secure, and highly interactive web applications
  • Own and evolve core platform modules, from concept through release and support
  • Influence application and system architecture with a focus on performance, reliability, security, and maintainability
  • Lead by example through clean, well-tested code, thoughtful design reviews, and pragmatic technical decisions
  • Collaborate closely with Product Management, QA, and other engineers throughout the SDLC
  • Provide technical mentorship and guidance to other engineers on the team
  • Diagnoses and resolves complex production issues across distributed systems
  • Ensure solutions meet eClinical Solutions quality standards and applicable industry regulations
  • Contribute to technical documentation including design specs, acceptance criteria, and release notes

Take the first step towards your dream career. Here is what we are looking for in this role.
AI & Modern Engineering Focus
We're actively incorporating AI-powered capabilities into our platform, and you'll help shape how this is done responsibly and effectively in an enterprise environment. This includes:
  • Integrating LLMs and AI services into .NET- and Python-based systems
  • Designing and implementing AI-assisted workflows, copilots, or intelligent automation features
  • Working with agentic AI patterns (e.g., task orchestration, tool-using agents, workflow automation)
  • Applying prompt engineering, evaluation techniques, and guardrails to ensure reliability and compliance
  • Collaborating with data and platform teams to operationalize AI-not just prototype it

Deep ML expertise is not required-we're looking for strong engineers who understand how to apply AI capabilities in real products.
What We're Looking For
  • Bachelor's or Master's degree in Computer Science or equivalent practical experience preferred
  • Expert-level proficiency in C#, .NET, and ASP.NET (MVC/Web APIs)
  • 3-5 years of experience in software design and development using the Microsoft technology stack.
  • Strong experience building full-stack web applications (Angular, TypeScript, HTML, CSS)
  • Solid understanding of software design principles, patterns, and best practices
  • Experience across the full Software Development Lifecycle (Agile preferred)
  • Proven ability to work independently while collaborating effectively in a fast-paced environment
  • Excellent communication, documentation, and technical leadership skills

AI & Platform Experience
  • Hands-on experience integrating LLM-based services (e.g., OpenAI, Azure OpenAI, or similar) into applications
  • Experience using Python and/or .NET alongside AI/LLM workflows
  • Familiarity with agent-based or workflow-driven AI architectures is a strong plus
  • Understanding of secure and responsible AI usage in enterprise systems

Nice to Have
  • Strong SQL expertise (Microsoft SQL Server preferred), including performance tuning
  • Experience with microservices, distributed systems, and cloud platforms (AWS preferred)
  • Secure development experience, including awareness of common vulnerabilities and mitigations
  • Experience with clinical trial data, life sciences, or regulated SaaS environments
  • Experience building data visualizations or analytics-driven user experiences

Accelerate your skills and career within a fast-growing company while impacting the future of healthcare. We have shared our story, now we look forward to learning yours!
eClinical is a winner of the 2025 Top Workplaces USA Award for Remote Work! We have also received numerous Top Workplaces Culture Excellence Awards celebrating our exceptional company vision, values, and work-life balance. See all the details here: https://topworkplaces.com/company/eclinical-solutions/
eClinical Solutions is a people first organization. Our inclusive culture values the contribution that diversity brings to our business. We celebrate individual experiences that connect us and that inspire innovation in our community. Our team seeks out opportunities to learn, grow and continuously improve. Bring your authentic self, you are welcome here!
We are proud to be an equal opportunity employer that values diversity. Our management team is committed to the principle that employment decisions are based on qualifications, merit, culture fit and business need.
#LI-AB1
Pay Range
US Pay Ranges
$132,000-$165,000 USD