1

Senior Python Software Engineer Jobs in Louisville, KY

Senior Software Engineer

Louisville, KY · Remote

$117.70K - $155.20K/yr

NET, Python, and cloud technologies. This role ensures high availability and quality by ... The Senior Software Engineer will leverage industry best practices in software development, system ...

Senior Software Engineer

Louisville, KY · Remote

$117.70K - $155.20K/yr

NET, Python, and cloud technologies. This role ensures high availability and quality by ... The Senior Software Engineer will leverage industry best practices in software development, system ...

Senior Software Engineer

Louisville, KY · Remote

$117.70K - $155.20K/yr

NET, Python, and cloud technologies. This role ensures high availability and quality by ... The Senior Software Engineer will leverage industry best practices in software development, system ...

Sr. Software Engineer

Louisville, KY · Remote

$150K - $175K/yr

SENIOR SOFTWARE ENGINEER POSITION SUMMARY We are seeking a Sr. Software Engineer and or Jr. Platform Architect to serve as technical lead responsible for day-to-day development, design, build, and ...

Software Engineer

Louisville, KY · On-site

$110K - $135K/yr

Software Engineer - ERP Systems (Python / Odoo) Location: Louisville, KY (Hybrid Preferred) Remote Option: Open to remote candidates who can travel onsite at least one week per quarter Company Size:

Sr. Software Engineer (Embedded Systems)

Louisville, KY · On-site

$119.10K - $156.10K/yr

* Lead a team of software engineers, providing technical guidance, mentorship, and support to ensure ... Python, and other tools. * Take ownership of software development projects, ensuring they are ...

Experience building backend services using languages such as C#, Python, or similar * Understanding of software engineering disciplines and the ability to work across multiple layers of the ...

Works with senior leadership to influence project timelines, deliverables, and strategic direction ... NET Framework 7+, .NET core and Python; familiarity with front-end technologies (HTML, CSS ...

Lead Software Engineer

Louisville, KY · Remote

$129.30K - $177.80K/yr

Works with senior leadership to influence project timelines, deliverables, and strategic direction ... NET Framework 7+, .NET core and Python; familiarity with front-end technologies (HTML, CSS ...

Works with senior leadership to influence project timelines, deliverables, and strategic direction ... NET Framework 7+, .NET core and Python; familiarity with front-end technologies (HTML, CSS ...

Sr. Software Engineer II

Louisville, KY · On-site

$117.50K - $155K/yr

The Sr. Software Engineer II will design, develop, test, deploy, and maintain software applications on the Waystar Claims platform, collaborating with cross-functional teams to translate business ...

Advise senior leadership (Directors, VPs) on engineering strategy and risk mitigation * Translate ... Java * .NET * Python * Full-stack development across UI, APIs, and backend services * Experience ...

Advise senior leadership (Directors, VPs) on engineering strategy and risk mitigation * Translate ... Java * .NET * Python * Full-stack development across UI, APIs, and backend services * Experience ...

Senior .NET Software Engineer

New Albany, IN · On-site +1

$113.40K - $149.40K/yr

Software engineering * C/C++/Java/.NET * Agile methodologies * Technical documentation * ... WHAT DO WE OFFER? * Join our team and culture GMV by entering into technological and innovative projects ...

Sr. Software Engineer II

Louisville, KY · On-site

$117.70K - $155.20K/yr

Contribute to the continuous improvement of Waystar's software development processes, tools, and infrastructure. * Mentor junior engineers and share knowledge within the team, fostering a culture of ...

Sr. Software Engineer II

Louisville, KY · On-site

$117.70K - $155.20K/yr

Contribute to the continuous improvement of Waystar's software development processes, tools, and infrastructure. * Mentor junior engineers and share knowledge within the team, fostering a culture of ...

Our platform offers an engaging blend of flexibility and challenge: you'll work closely with state-of-the-art AI models to take on programming tasks that include creating and solving challenging ...

Sr. Software Engineer II

Louisville, KY · On-site

$117.70K - $155.20K/yr

Bachelor's or Master's degree in Computer Science, Software Engineering, or a related technical field. * 7+ years of professional software development experience with a proven track record of ...

next page

Showing results 1-20

Senior Python Software Engineer information

See Louisville, KY salary details

$52.8K

$136.4K

$187.4K

How much do senior python software engineer jobs pay per year?

As of May 30, 2026, the average yearly pay for senior python software engineer in Louisville, KY is $136,414.00, according to ZipRecruiter salary data. Most workers in this role earn between $116,700.00 and $157,100.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Python Software Engineer, and why are they important?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What are some common challenges faced by Senior Python Software Engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What does a Senior Python Software Engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are popular job titles related to Senior Python Software Engineer jobs in Louisville, KY? For Senior Python Software Engineer jobs in Louisville, KY, the most frequently searched job titles are:
Senior Software Engineer

Senior Software Engineer

Humana

Louisville, KY • Remote

$117.70K - $155.20K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 19 days ago


Humana rating

7.9

Company rating: 7.9 out of 10

Based on 250 frontline employees who took The Breakroom Quiz

155th of 259 rated insurance


Job description

Become a part of our caring community
The Senior Software Engineer will work on the development and maintenance of robust, compliant software solutions using .NET, Python, and cloud technologies. This role ensures high availability and quality by standardizing processes, resolving complex issues, and fostering cross-team collaboration.

Location: This position is primarily work-from-home (WAH); however, candidates must be based in and able to work from Louisville, KY; Dallas, TX; or Nashville, TN. Occasional in-office presence may be required based on business needs.

The Senior Software Engineer will leverage industry best practices in software development, system architecture, and technical leadership to deliver reliable and compliant solutions. This role is instrumental in maintaining high availability and regulatory standards across our pharmacy benefit platforms. The engineer will provide hands-on expertise in both new development and ongoing maintenance, utilizing technologies such as .NET, Python, and cloud services (e.g., Azure or GCP). Responsibilities include promoting cross-team collaboration, facilitating knowledge transfer, and minimizing operational risks. The Senior Software Engineer will standardize quality assurance processes, oversee testing and debugging, and implement effective solutions for complex software issues


Use your skills to make an impact

Required Qualifications

  • Bachelor's degree in computer science or related field or equivalent experience.
  • At least 5+ years of experience in .NET application development. Familiarity with front-end technologies (HTML, CSS, JavaScript, Angular).
  • Experience with cloud infrastructure (Azure, GCP), APIs, containerization (Docker), orchestration (Kubernetes), and Infrastructure as Code (Terraform, Ansible, CloudFormation).
  • Hands-on experience in PostgreSQL for database management and operations.
  • Expertise with Git and DevOps for version control and collaboration within a DevOps environment. Hands-on expertise in building and maintaining CI/CD pipelines.
  • Excellent analytical, communication, organizational, and problem-solving abilities.
  • Knowledge of the healthcare domain, including industry standards and regulations.
  • Demonstrated experience with agile methodologies and project management principles.
  • Must be passionate about contributing to an organization focused on continuously improving consumer experiences.

Preferred Qualifications

  • Hands-on expertise with prompt engineering, large language models, and emerging AI trends.
  • Knowledge of artificial intelligence (AI) implementation, testing, and monitoring processes.
  • Hands-on experience utilizing Pyspark, Databricks, and Streamsets for large-scale data processing and pipeline development.
  • Practical experience with Kafka for implementing messaging and data streaming solutions.
  • Knowledge of Snowflake and Power BI for data warehousing and business intelligence solutions.
Travel: While this is a remote position, occasional travel to Humana's offices for training or meetings may be required.

Scheduled Weekly Hours

40

Pay Range

The compensation range below reflects a good faith estimate of starting base pay for full time (40 hours per week) employment at the time of posting. The pay range may be higher or lower based on geographic location and individual pay will vary based on demonstrated job related skills, knowledge, experience, education, certifications, etc.


$106,900 - $147,000 per year


This job is eligible for a bonus incentive plan. This incentive opportunity is based upon company and/or individual performance.

Description of Benefits

Humana, Inc. and its affiliated subsidiaries (collectively, "Humana") offers competitive benefits that support whole-person well-being. Associate benefits are designed to encourage personal wellness and smart healthcare decisions for you and your family while also knowing your life extends outside of work. Among our benefits, Humana provides medical, dental and vision benefits, 401(k) retirement savings plan, time off (including paid time off, company and personal holidays, volunteer time off, paid parental and caregiver leave), short-term and long-term disability, life insurance and many other opportunities.
About us
About Humana: Humana Inc. (NYSE: HUM) is a leading U.S. healthcare company. Through our Humana insurance services and our CenterWell healthcare services, we make it easier for the millions of people we serve to achieve their best health - delivering the care and service they need, when they need it. These efforts are leading to a better quality of life for people with Medicare and Medicaid, families, individuals, military service personnel, and communities at large. Learn more about what we offer atHumana.comand atCenterWell.com.


Equal Opportunity Employer

It is the policy of Humana not to discriminate against any employee or applicant for employment because of race, color, religion, sex, sexual orientation, gender identity, national origin, age, marital status, genetic information, disability or protected veteran status. It is also the policy of Humana to take affirmative action, in compliance with Section 503 of the Rehabilitation Act and VEVRAA, to employ and to advance in employment individuals with disability or protected veteran status, and to base all employment decisions only on valid job requirements. This policy shall apply to all employment actions, including but not limited to recruitment, hiring, upgrading, promotion, transfer, demotion, layoff, recall, termination, rates of pay or other forms of compensation and selection for training, including apprenticeship, at all levels of employment.


What Humana employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


Humana logo

About Humana

Sourced by ZipRecruiter

Humana Inc., headquartered in Louisville, KY., is a leading health care company that offers a wide range of insurance products and health and wellness services that incorporate an integrated approach to lifelong well-being. By leveraging the strengths of its core businesses, Humana believes it can better explore opportunities for existing and emerging adjacencies in health care that can further enhance wellness opportunities for the millions of people across the nation with whom the company has relationships.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Louisville, KY, US

Year founded

1961

Social media