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Senior Python Full Stack Developer Jobs in Knoxville, TN

Varsity Tutors

JavaScript Tutor

Knoxville, TN · Remote

$18 - $40/hr

Ability to explain callback functions, scope and hoisting, and the event loop while preparing students for web development careers and full-stack engineering coursework. * Conceptual Teaching ...

Vital IT Services

Software Engineer (Remote)

Oak Ridge, TN · Remote

$95K - $115K/yr

Professional Core Experience: 3-6 years of verified full-stack or backend software engineering ... We actively invest in our engineers' career trajectories into senior engineering or architecture ...

TEKsystems

Network Engineer

Knoxville, TN · Hybrid

$44 - $50/hr

Description Seeking a Sr Network Engineer to support the wired and wireless network infrastructure ... As an industry leader in Full-Stack Technology Services, Talent Services, and real-world ...

FC Renew

Senior Scientist

Knoxville, TN · On-site

$87K - $119K/yr

Utilizing electrochemical diagnostics to conduct in-situ testing of fuel cell stacks * Working with ... Experience with programming Python, Lab View, Matlab, and/or similar * Exceptional interpersonal ...

FC Renew

Senior Scientist

Knoxville, TN · Hybrid

$87K - $119K/yr

Utilizing electrochemical diagnostics to conduct in-situ testing of fuel cell stacks * Working with ... Experience with programming Python, Lab View, Matlab, and/or similar * Exceptional interpersonal ...

Launch Tennessee

Senior Scientist

Knoxville, TN · On-site

$85 - $110/hr

Utilize electrochemical diagnostics to conduct in‑situ testing of fuel cell stacks. * Work with ... Experience with programming Python, LabView, MATLAB, and/or similar. * Exceptional interpersonal ...

New

Varsity Tutors

Supabase Tutor

Knoxville, TN · Remote

$18 - $40/hr

Adapts instruction using database design exercises, authentication implementation tutorials, and full-stack project development to support developers from Supabase beginners through advanced users ...

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Senior Python Full Stack Developer information

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How much do senior python full stack developer jobs pay per year?

As of Aug 19, 2026, the average yearly pay for senior python full stack developer in Knoxville, TN is $123,880.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,000.00 and $144,100.00 per year, depending on experience, location, and employer.

What is a senior Python full stack developer?

Senior Python Full Stack Developers are experienced software engineers who specialize in both frontend and backend web development using Python and related technologies. They are responsible for designing, building, and maintaining complex web applications, often leading teams and making architectural decisions. Their expertise typically includes frameworks like Django or Flask for backend development, as well as JavaScript frameworks such as React or Angular for the frontend. In addition to coding, they often mentor junior developers and ensure best practices in software development. Their role requires a deep understanding of databases, APIs, deployment processes, and modern development workflows.

What are the key skills and qualifications needed to thrive as a senior Python full stack developer?

To thrive as a Senior Python Full Stack Developer, you need advanced proficiency in Python, JavaScript frameworks (such as React or Angular), database management, and a solid understanding of both front-end and back-end development principles, often backed by a degree in computer science or related experience. Familiarity with tools like Django or Flask, RESTful APIs, version control systems (e.g., Git), and cloud platforms is typically required. Excellent problem-solving abilities, effective communication, and the ability to mentor junior developers are standout soft skills for this role. These skills ensure robust, scalable applications and foster effective collaboration across technical teams, driving project success.

What are some common challenges faced by senior Python full stack developers when working on cross-functional teams?

Senior Python Full Stack Developers often collaborate with designers, product managers, and DevOps specialists, which can present challenges in aligning technical solutions with business goals and user experience expectations. Balancing backend performance with frontend responsiveness and maintaining clear communication across disciplines are key hurdles. Additionally, staying updated with rapidly evolving frameworks and ensuring code quality and scalability across the stack requires continual learning and adaptability. Successful developers proactively bridge these gaps by fostering open dialogue and advocating for best practices throughout the development process.

What is the difference between Senior Python Full Stack Developer vs Backend Developer?

AspectSenior Python Full Stack DeveloperBackend Developer
Required SkillsProficiency in Python, JavaScript, HTML/CSS, frameworks like Django/Flask, React or AngularStrong Python skills, experience with server-side development, databases, APIs
Work EnvironmentFull-stack development across front-end and back-end, often in agile teamsPrimarily server-side, database, and API development
Industry UsageTech companies, startups, enterprises needing full-stack solutionsWeb services, SaaS, enterprise applications

The main difference is that a Senior Python Full Stack Developer handles both front-end and back-end development, requiring skills in multiple technologies, while a Backend Developer focuses mainly on server-side logic, databases, and APIs. The full-stack role demands broader expertise, whereas backend roles are more specialized in server-side development.

What are popular job titles related to Senior Python Full Stack Developer jobs in Knoxville, TN?

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Cities near Knoxville, TN with the most Senior Python Full Stack Developer job openings:

Senior Python Full Stack Developer jobs near you

Research Software Engineer

Oak Ridge National Laboratory

Oak Ridge, TN • On-site

$177K/yr

Other

Re-posted yesterday

Oak Ridge National Laboratory rating

8.8

Company rating: 8.8 out of 10

Based on 16 frontline employees who took The Breakroom Quiz

14th of 120 rated laboratories

Job description

Requisition Id 16231
Overview:
The National Center for Computational Sciences (NCCS) at Oak Ridge National Lab (ORNL), which hosts several of the world's most powerful computer systems, is seeking highly qualified individuals to play a key role in developing, and deploying data management tools and persistent services that support scientific and AI/ML campaigns that run on NCCS computing infrastructure, including the world's first exaflop system, Frontier.
The Team:
As a Research Software Engineer (RSE) in the Data and Platform Services (DAPS) group, you will work within the HPC Operations Section and closely collaborate with other Lead Software Engineers on various software engineering projects. The DAPS group designs and operates data management platforms, tools, and services for the end-to-end data lifecycle from ingestion to publication and supports several large initiatives and facilities at ORNL. Our primary development and deployment platform is the Oak Ridge Leadership Computing Facility (OLCF) Slate Service, built on Kubernetes and Rancher, which provides a container orchestration service for running critical operation applications and user-managed persistent applications that run alongside our OLCF supercomputer systems and other OLCF managed HPC clusters.
The Role:
As a Research Software Engineer, you will implement, operate, and maintain federated data platforms, data management portals, data processing pipelines, API gateways, and persistent services for the entire data lifecycle on our on-premises Kubernetes clusters, with a strong focus on scalability, reliability, and maintainability. You will also assist with AI initiatives at OLCF, integrate key data engineering and MLOps technologies, be an individual contributor for small-medium sized projects, and collaborate with Platform engineers in delivering a robust set of production services for OLCF users. This role requires: significant experience with full stack application and API development, working knowledge of Kubernetes and containerization. Knowledge of current AI/ML tools and workflows is preferred but not required.
Major Duties/Responsibilities:
Application Development and Deployment
  • Gain working expertise with federated data management (e.g., Pelican, Rucio), data catalog solutions (e.g. CKAN, DKAN, Schema.org), streaming data (e.g., Kafka), and data movement (XRootD, Globus, S3) tools and technologies.
  • Design and implement web portals and API services for data management using a combination of modern web technologies.
  • Develop, implement, and maintain Kubernetes deployment recipes for data portals, catalogs, API gateways, and other ancillary services like key-value stores and databases.
  • Implement solutions for MLOps including model lifecycle management and storage, as well as integration with existing platforms like MLFlow.

Collaboration
  • Partner closely with internal platforms, cybersecurity, and account management teams to ensure the platform meets security, compliance, role-based access controls, and usability expectations.
  • Participate in cross-functional projects related to platform enhancements and cluster lifecycle automation.
  • Be able to represent the DAPS team with internal collaborators and partners across the lab.

Basic Qualifications:
  • BS degree and 3+ years of relevant experience or equivalent experience.
  • At least two years of experience with data management platform and tools development.
  • At least two years of experience with full stack application and API development.
  • Experience with CI/CD tooling, GitOps, and Kubernetes.
  • Experience with code review and familiarity with tools like git, GitHub and GitLab.

Preferred Qualifications:
  • Excellent interpersonal/communications skills, and the ability to work as part of a team.
  • Experience implementing and maintaining highly available systems/services.
  • Experience with PHP, Python, modern Javascript frameworks (React, AngularJS, NodeJS).
  • 5+ years of experience in addition to the degree.
  • Experience with modern software practices such as test-driven development, Agile software development practices and a firm, proven knowledge of software development lifecycles.
  • Demonstrated activity within the broader open-source software community.

This position will remain open for a minimum of 5 days after which it will close when a qualified candidate is identified and/or hired.
We accept Word (.doc, .docx), Adobe (unsecured .pdf), Rich Text Format (.rtf), and HTML (.htm, .html) up to 5MB in size. Resumes from third party vendors will not be accepted; these resumes will be deleted and the candidates submitted will not be considered for employment.
If you have trouble applying for a position, please email
ORNL is an equal opportunity employer. All qualified applicants, including individuals with disabilities and protected veterans, are encouraged to apply. UT-Battelle is an E-Verify employer.

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