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Senior Python Flask Developer Jobs in Massachusetts

Saviance

Senior DevOps Engineer

Boston, MA · On-site

$141K - $181K/yr

Saviance is seeking a Senior DevOps Engineer to enhance their platform infrastructure. The role ... Python, JavaScript, etc. • Hands-on experience with Docker, Docker Compose, Docker Swarm ...

Motion Recruitment

Senior DevOps Engineer

Danvers, MA · On-site

$137K - $176K/yr

A well-known medical device manufacturer is looking for a full-time Senior DevOps Engineer to join ... Solid programming skills in C, Python, and Bash * Experience with DevOps tooling spanning ...

Goodwin

Sr. AI Developer

Boston, MA · On-site

$59.25 - $78.25/hr

We're seeking a product-minded Senior AI Engineer to build and scale production-grade AI agents and ... NET, Python, and TypeScript/React, writing well-structured services, clean APIs, and tested code ...

ICS Global Soft INC

Senior Data Engineer

Boston, MA · On-site +1

$115K - $156K/yr

Data Engineer & Senior Data Engineer Location: Remote or Boston, MA & San Mateo, CA Duration: FTE ... Idealcandidate will be strong in SQL, python, tableau, Qlik or another cloud DV tooland mid (Boston ...

STR

Senior DevOps Engineer

Woburn, MA · On-site

$134K - $184K/yr

As a Senior DevOps Engineer you will establish and maintain a continuous integration / continuous ... Implement automated build systems for C/C++ and Python codebases using CMake, Conan, and similar ...

SS&C Technologies

Senior Software Engineer

Waltham, MA · On-site

$132K - $174K/yr

Collaborate cross-functionally with product and engineering teams to solve real customer problems ... TypeScript, JavaScript (Node.js), Python, Java Frameworks: React, Spring Boot, Express, Flask APIs ...

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Senior Python Flask Developer information

What is a senior Python Flask developer?

Senior Python Flask Developers are experienced software engineers who specialize in building web applications using the Python programming language and the Flask web framework. They are responsible for designing, developing, and maintaining scalable backend systems, APIs, and web services. In addition to strong coding skills, they often lead projects, mentor junior developers, and ensure best practices in code quality, security, and performance. Their expertise allows them to solve complex technical challenges and contribute to the overall architecture and success of software projects.

What are the key skills and qualifications needed to thrive as a senior Python Flask developer, and why are they important?

To thrive as a Senior Python Flask Developer, you need advanced proficiency in Python, deep understanding of the Flask framework, and experience designing scalable backend architectures, typically supported by a degree in computer science or related field. Familiarity with RESTful API development, database management systems like PostgreSQL or MySQL, and version control tools such as Git is essential, and certifications in cloud platforms or web development can be beneficial. Strong problem-solving skills, clear communication, and the ability to mentor junior developers are standout soft skills for this role. These abilities ensure efficient delivery of robust, maintainable web applications and foster productive collaboration within development teams.

What are some common challenges faced by senior Python Flask developers when working on large-scale applications?

Senior Python Flask Developers often encounter challenges such as managing complex codebases, ensuring scalability, and maintaining performance as applications grow. Integrating Flask with other technologies (like databases, caching systems, or third-party APIs) can introduce architectural complexities. Additionally, balancing rapid development with writing maintainable, well-tested code is crucial. Collaboration with frontend developers, DevOps, and QA teams is frequent, requiring strong communication and problem-solving skills.

What is the difference between Senior Python Flask Developer vs Python Developer?

AspectSenior Python Flask DeveloperPython Developer
Required CredentialsBachelor's in CS or related, experience with Flask, REST APIsBachelor's in CS or related, basic Python knowledge
Work EnvironmentWeb development teams, startups, tech companiesSoftware development teams, startups, tech companies
Employer & Industry UsageTech firms, SaaS companies, startupsVariety of industries including finance, healthcare, tech
Search & Comparison IntentAdvanced roles, leadership, project scopeEntry to mid-level development, learning

The main difference between a Senior Python Flask Developer and a Python Developer lies in experience and responsibilities. Senior developers typically have more expertise in Flask, lead projects, and mentor junior staff, whereas Python Developers may focus on coding and basic application development. Both roles are essential in web development teams, but senior roles require deeper knowledge and leadership skills.

What are popular job titles related to Senior Python Flask Developer jobs in Massachusetts?

For Senior Python Flask Developer jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Senior Python Flask Developer jobs in Massachusetts look for?

The top searched job categories for Senior Python Flask Developer jobs in Massachusetts are:

What cities in Massachusetts are hiring for Senior Python Flask Developer jobs?

Cities in Massachusetts with the most Senior Python Flask Developer job openings:

Senior Python Flask Developer jobs near you

Senior Software Engineer, Applied AI

Cambridge, MA • On-site

Lila Sciences
See more jobs at Lila Sciencesexternal

$144K - $270K/yr

Full-time

Medical, Dental, Vision, Life

Re-posted 15 days ago

Key responsibilities

  • Design and deploy backend services and data pipelines that support advanced AI applications such as LLMs, RAG, and agentic frameworks.

  • Build high-performance APIs and microservices to enable integration between AI models, scientific tools, and user-facing applications.

  • Architect and manage scalable data pipelines for structured, unstructured, and vectorized data to support AI/ML workloads.

Job description

Your Impact at LILA
We are seeking a Senior Software Engineer to join our Applied AI group and help build the next generation of our AI-driven scientific platform. In this role, you will design and optimize the backend systems, data pipelines, and AI integrations that power intelligent, data-driven applications. You'll work at the intersection of backend engineering and machine learning, ensuring our platform seamlessly scales and supports cutting-edge applied AI techniques such as Retrieval-Augmented Generation (RAG), agentic AI, and large language model (LLM) integration.
This role is ideal for someone who thrives in bridging software engineering and applied AI-turning research into production-grade systems that drive real-world scientific discovery. If you are passionate about building performant, elegant systems that make AI useful and impactful, we would love to hear from you!
What You'll Be Building
  • Applied AI Integration: Design and deploy backend services and data pipelines that directly support advanced AI applications, including LLMs, RAG, and agentic frameworks.
  • API & Service Development: Build high-performance APIs and microservices that enable seamless integration between AI models, scientific tools, and user-facing applications.
  • Data Pipeline Architecture: Architect and manage scalable pipelines capable of handling structured, unstructured, and vectorized data for AI/ML workloads.
  • Database & Knowledge Systems: Implement and optimize SQL, NoSQL, and vector databases to support low-latency AI retrieval and inference workloads.
  • Cloud & Infrastructure: Leverage AWS, Kubernetes, and infrastructure-as-code (Terraform/CloudFormation) to build robust, production-ready AI platforms.
  • Performance & Reliability: Diagnose system bottlenecks, optimize for cost and speed, and ensure the reliability and fault-tolerance of AI-driven workflows.
  • Collaboration: Partner with ML researchers, platform engineers, and scientists to translate models and algorithms into scalable, production-ready systems.

What You'll Need to Succeed
  • Educational Background: Bachelor's or Master's in Computer Science, Engineering, or a related field.
  • Backend & Data Expertise: 7+ years of professional experience building and scaling production systems, including APIs, data pipelines, and distributed services.
  • Programming Skills: Strong Python skills (FastAPI, Flask, Django), with solid experience in backend service development.
  • Databases: Proven experience with SQL, NoSQL, and vector databases; skilled in schema design, indexing, and query optimization.
  • Applied AI Systems: Hands-on experience integrating ML models or AI-driven workflows into production services.
  • Cloud & DevOps: Proficiency with AWS, Docker/Kubernetes, CI/CD pipelines, and infrastructure-as-code.
  • Communication & Problem-Solving: Ability to work cross-functionally with diverse teams and explain complex technical concepts to non-experts.

Bonus Points For
  • Scientific & Data-Intensive Domains: Experience working with life sciences, materials sciences, or other research-heavy fields.
  • Startup Experience: Comfort with fast-paced, iterative environments where impact and adaptability matter.

Compensation
We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.
U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.
Expected Base Salary Range
$144,000-$270,000 USD
About LILA
Lila Sciences is building Scientific Superintelligenceâ„¢ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factoryâ„¢ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
We're All In
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

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