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Senior Python Engineer Jobs in Annapolis, MD (NOW HIRING)

Polar IT Services

Python Integration Developer

Hanover, MD · On-site +1

$50 - $69/hr

Mid-Senior It's a W2 Role Job Summary We are seeking an experienced Integration Developer with strong Python development skills to build and support enterprise integrations across cloud platforms and ...

Leidos

Junior Python Developer

Columbia, MD · On-site

$69K - $125K/yr

Junior Python Developer Who We Are: Kudu Dynamics is Leidos Owned Company, forged out of a decade ... Collaborate with senior developers and DevOps engineers * Assist with onboarding technical ...

IntelliDyne

SQL and Python Developer

Washington, DC

$90K - $125K/yr

SQL and Python Developer Location: Washington, DC Classification: Exempt Position Summary The ... in senior level position supporting open systems Oracle environments * Minimum 5 years SQL and PL ...

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Showing results 41-60

All JobsPython Engineer JobsSenior Python Engineer JobsSenior Python Engineer Jobs in Annapolis, MD

Senior Python Engineer information

See Annapolis, MD salary details

$54.4K

$140.5K

$193K

How much do senior python engineer jobs pay per year?

As of Sep 2, 2026, the average yearly pay for senior python engineer in Annapolis, MD is $140,545.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,300.00 and $161,900.00 per year, depending on experience, location, and employer.

What does a senior Python engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the key skills and qualifications needed to thrive as a senior Python engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What are the common challenges senior Python engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.

What job categories do people searching Senior Python Engineer jobs in Annapolis, MD look for?

The top searched job categories for Senior Python Engineer jobs in Annapolis, MD are:

What cities near Annapolis, MD are hiring for Senior Python Engineer jobs?

Cities near Annapolis, MD with the most Senior Python Engineer job openings:

Senior Python Engineer jobs near you
Infographic showing various Senior Python Engineer job openings in Annapolis, MD as of August 2026, with employment types broken down into 89% Full Time, 8% Part Time, and 3% Contract. Highlights an 83% Physical, 5% Hybrid, and 12% Remote job distribution, with an average salary of $140,545 per year, or $67.6 per hour.

Python Software Engineer [$224k/yr+] S with Security Clearance

SYSTOLIC

Annapolis Junction, MD • On-site

$224K/yr

Other

Posted 26 days ago

Job description

Candidates must already possess an active Secret clearance to be considered. Summary: • Senior Software Engineer position for AI integration and agentic platform development. • Focuses on Python backend development, Kubernetes container orchestration, and applied AI integration using LLMs, Model Context Protocol (MCP), and Retrieval-Augmented Generation (RAG). • Utilizes additional technologies including Java, Spring, Git, Docker, Linux, LangChain, NiFi, Kafka, AWS, Azure, SQL, PostgreSQL, and MySQL. Qualifications & Compensation: • At least 5 years of experience in Software Engineering with a strong focus on Python backend development and a Bachelor's degree in a related field (or equivalent combination of education and experience). • Total Compensation: $224k+ yearly Job Description: • Design and develop Python-based components for a core agentic platform. • Deploy, manage, and scale applications within Kubernetes (K8s) environments. • Build Model Context Protocol (MCP) servers and a library of reusable skills (function calling/tools) that enable AI agents to safely interact with internal databases, microservices, and external APIs. • Collaborate with cross-functional teams to help them expose their Java-based APIs to AI agents. • Implement strict enterprise AI guardrails, ensuring data privacy, sensitive data scrubbing, prompt injection defenses, and output validation. • Maintain strong testing skills, including automated testing pipelines for non-deterministic AI outputs. • Integrate commercial LLM APIs (e.g., OpenAI, Anthropic) or open-source models into production backend applications. • Apply modern AI concepts such as prompt engineering, agents, function-calling/tool-use, and Retrieval-Augmented Generation (RAG). • Design enterprise APIs, RESTful web services, and Microservices architecture. • Utilize configuration management tools including Git, CI/CD pipelines, and Docker. • Work comfortably on a Linux command line. • Assist teams in connecting components to the agent platform using Java frameworks (e.g., Spring). • Utilize Python-based AI integration frameworks (e.g., LangChain, LlamaIndex, CrewAI, AutoGen). • Work with Vector Databases, semantic caching, AI observability tools, NiFi, Kafka, and cloud-based infrastructure (AWS, Azure). • Work with SQL databases (e.g., Postgres, MySQL), distributed databases, or NoSQL databases. • Maintain DoD 8140 / 8570 IAT Level II compliance certifications if required. • Must be able to obtain and maintain a U.S. Government Security Clearance, with active Secret or Top Secret clearance preferred. Telework: This position supports a hybrid work arrangement, requiring an average of 1-2 days per week in the office. About SYSTOLIC: SYSTOLIC is dedicated to giving our employees the best possible company experience so that they can focus on providing outstanding support to their customer’s mission. Our company is founded on integrity, enthusiasm, and a relentless commitment to supporting the Intelligence Community. You can learn more about us and submit an application to be considered against our current and future openings at https://systolic.com. To learn about our compensation ranges, visit our Pay Transparency page at: https://systolic.com/pay-transparency

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