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Senior Python Engineer Jobs in Annapolis, MD (NOW HIRING)

Python Engineer, Agentic AI

Washington, DC · On-site +1

$142K - $213K/yr

You will work closely with senior engineers and product partners to design, develop, test, and ... Write clean, well-structured, and maintainable Python code that follows established coding ...

Python Engineer, Agentic AI

Washington, DC · On-site +1

$142K - $213K/yr

You will work closely with senior engineers and product partners to design, develop, test, and ... Write clean, well-structured, and maintainable Python code that follows established coding ...

Sr. Software Engineer (Python)

Baltimore, MD · Hybrid

$120K - $162K/yr

Extensive experience with Python frameworks and tools (e.g., NumPy, Pandas). * Strong analytical and problem-solving skills with a results-oriented mindset. * Familiarity with multiple programming ...

Showing results 21-40

Senior Python Engineer information

See Annapolis, MD salary details

$54.4K

$140.5K

$193K

How much do senior python engineer jobs pay per year?

As of Aug 11, 2026, the average yearly pay for senior python engineer in Annapolis, MD is $140,545.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,300.00 and $161,900.00 per year, depending on experience, location, and employer.

Are senior Python engineers in demand?

Senior Python engineers are highly in demand due to the language's widespread use in web development, data analysis, machine learning, and automation. Companies seek experienced developers with strong problem-solving skills and knowledge of frameworks like Django or Flask, making this a competitive and growing field.

What are the key skills and qualifications needed to thrive as a senior Python engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What does a senior Python engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the common challenges senior Python engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.
What cities near Annapolis, MD are hiring for Senior Python Engineer jobs? Cities near Annapolis, MD with the most Senior Python Engineer job openings:
Infographic showing various Senior Python Engineer job openings in Annapolis, MD as of August 2026, with employment types broken down into 89% Full Time, 7% Part Time, and 4% Contract. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution, with an average salary of $140,545 per year, or $67.6 per hour.

Software Engineer - Python

Interclypse Inc.

Annapolis Junction, MD • On-site

$49.75 - $68.50/hr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 5 hours ago


Job description

Job Type
Full-time
Description
Interclypse is seeking a Senior Python Developer to support a federal agency's migration from a legacy OpenVMS/Itanium server infrastructure and DCL scripting environment to a modern Python-based middleware platform. You will work as part of a small, senior developer team under the agency's technical direction, writing production-quality Python code within a disciplined Agile/DevSecOps framework. This is a Firm-Fixed-Price engagement - we expect self-directed professionals who take ownership of deliverables and meet acceptance criteria without heavy management oversight.nt.
Key Responsibilities
• Develop Python/FastAPI middleware services that replace legacy OpenVMS DCL script processing, including POLLVAX, TO_FDSYS, and other identified batch scripts
• Build file processing pipelines, data routing engines, hot folder watchers, and workflow management components
• Implement a dual-mode delivery system supporting both legacy share emulation and modern REST API access
• Develop SSO-integrated authentication and authorization, user and role management, and audit logging
• Create Axway FTP server integration for congressional file intake and Windows NAS connectivity for file storage
• Build task queuing systems, database integration for metadata tracking, and event-driven processing with real-time file monitoring
• Implement automated backup, error recovery/retry mechanisms, and performance optimization for concurrent client connections
• Design and execute a comprehensive testing framework including unit, integration, and UAT automated test suites
• Participate in 2-week Agile sprints, bi-weekly demos, and DevSecOps gates under agency direction
• Contribute to monthly status reports, development logs, sprint code releases, and support documentation
Requirements
Interclypse provides a uniquely cultivating environment where mentorship and continued learning create extraordinary professionals. Our goal is to empower our talent by putting you in the driver's seat of your career.
Software Engineering candidates have experience working in team environments, building software solutions for customers, and are looking to take their careers to the next level. Familiarity with the following tech stacks below is great but not a requirement.
Required Qualifications
• Develop Python/FastAPI middleware services that replace legacy OpenVMS DCL script processing, including POLLVAX, TO_FDSYS, and other identified batch scripts
• Build file processing pipelines, data routing engines, hot folder watchers, and workflow management components
• Implement a dual-mode delivery system supporting both legacy share emulation and modern REST API access
• Develop SSO-integrated authentication and authorization, user and role management, and audit logging
• Create Axway FTP server integration for congressional file intake and Windows NAS connectivity for file storage
• Build task queuing systems, database integration for metadata tracking, and event-driven processing with real-time file monitoring
• Implement automated backup, error recovery/retry mechanisms, and performance optimization for concurrent client connections
• Design and execute a comprehensive testing framework including unit, integration, and UAT automated test suites
• Participate in 2-week Agile sprints, bi-weekly demos, and DevSecOps gates under agency direction
• Contribute to monthly status reports, development logs, sprint code releases, and support documentation
Preferred Qualifications
• Develop Python/FastAPI middleware services that replace legacy OpenVMS DCL script processing, including POLLVAX, TO_FDSYS, and other identified batch scripts
• Build file processing pipelines, data routing engines, hot folder watchers, and workflow management components
• Implement a dual-mode delivery system supporting both legacy share emulation and modern REST API access
• Develop SSO-integrated authentication and authorization, user and role management, and audit logging
• Create Axway FTP server integration for congressional file intake and Windows NAS connectivity for file storage
• Build task queuing systems, database integration for metadata tracking, and event-driven processing with real-time file monitoring
• Implement automated backup, error recovery/retry mechanisms, and performance optimization for concurrent client connections
• Design and execute a comprehensive testing framework including unit, integration, and UAT automated test suites
• Participate in 2-week Agile sprints, bi-weekly demos, and DevSecOps gates under agency direction
• Contribute to monthly status reports, development logs, sprint code releases, and support documentation
Our favorite candidates are resilient problem solvers, cooperative teammates, and passionate innovators.
Why You Might Like This Job:
  • You're tired of working for a massive organization.
  • You want to work for an established company that values your stable career.
  • You want to work with a team that loves their job and making cool stuff.
  • You want to be part of a team focused on making a positive impact.
  • You want to grow your skills in management or work toward becoming an expert.
  • You want to have the option for career mentorship, both in technology and in business.
  • You value a company with a strong culture of growth and support

Benefits:
  • Employee Impact Program. Every employee has the opportunity to define and get rewarded for their contributions they can make toward the long-term health of the company, customer, and employee. This program in combination with our comprehensive time off and leave programs allow you to design a career and compensation program that enables near infinite flexibility while ensuring both company, customer, and individual health and prosperity.
  • Comprehensive time off and leave programs:
    • 31 Days (248 hours) of Paid Personal Time Off (PTO) for any vacation, holidays, illnesses, and birthdays
    • Parental Leave: 40 Hours
    • Bereavement Leave: 24 hours.
    • Military Reserve Leave (up to 80 hours, see employee handbook for details).
    • Jury Duty Leave 16 hours.
  • Retirement: Unlimited 401K match up to 8% of your salary up to the federal maximum
  • Health Insurance (Medical, Dental, Vision): Premium is 100% company paid (contact us for specific plan details).
  • Health Savings Account (HSA): Interclypse contributes $750 for individuals and $1500 for families
  • Vision Insurance
  • Dental Insurance includes orthodontics coverage
  • Life Insurance
  • Accidental Death and Dismemberment Insurance
  • Disability: Short-term and long-term disability coverage
  • Educational support: reimbursement up to the federal max of $5,250
  • Company apparel: $200 for company apparel each year
  • Social events: Holiday Party, Spring Picnic, Fall Picnic, happy hours and more

Interclypse isn't your typical company. We strive to have a positive & transformational impact on our community, our industry, and individuals. We keep this focus through our motto: "Doing What is Right". Apply today to see how you can join our winning team and start down the career path that's right for you!
EOE AA M/F/Vet/Disability:
Interclypse is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, creed, sex, sexual orientation, gender identity, national origin, disability, or protected Veteran status.
Related terms and topics: Java, Software Development, Computer Programming, Software Engineering, C++, Design Patterns, Enterprise Integration Patterns