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Senior Python Engineer Jobs in South Carolina (NOW HIRING)

EPC POWER CORP.

Senior Software Engineer

Fountain Inn, SC · On-site

$122K - $138K/yr

EPC Power is looking to add a Senior Software Engineer to our engineering team. In this role you ... Strong understanding of python * Strong understanding of electrical circuits * Interested in power ...

Atlas Tech

Senior Systems Engineer

North Charleston, SC · On-site

$99K - $136K/yr

The Senior Systems Engineer is responsible for the engineering, hardening, baseline enforcement ... Proficiency in scripting and programming languages (e.g., Python, Bash, PowerShell). * Experience ...

EPC POWER CORP.

Senior Software Engineer

Fountain Inn, SC · On-site

$122K - $138K/yr

Description EPC Power is looking to add a Senior Software Engineer to our engineering team. In this ... Strong understanding of python * Strong understanding of electrical circuits * Interested in power ...

Sunbelt Rentals

Sr. Software Engineer

Fort Mill, SC

$98K - $135K/yr

Write clean, well-tested Python for Function App APIs and custom connectors * Model and deliver ... Autonomy to own projects end to end, with senior engineers to collaborate with rather than report ...

Sunbelt Rentals, Inc.

Sr. Software Engineer

Fort Mill, SC · On-site

$98K - $135K/yr

Write clean, well-tested Python for Function App APIs and custom connectors * Model and deliver ... Autonomy to own projects end to end, with senior engineers to collaborate with rather than report ...

Sunbelt Rentals

Sr. Software Engineer

Fort Mill, SC

$98K - $135K/yr

Write clean, well-tested Python for Function App APIs and custom connectors * Model and deliver ... Autonomy to own projects end to end, with senior engineers to collaborate with rather than report ...

Sunbelt Rentals

Sr. Software Engineer

Fort Mill, SC · On-site

$98K - $135K/yr

Write clean, well-tested Python for Function App APIs and custom connectors * Model and deliver ... Autonomy to own projects end to end, with senior engineers to collaborate with rather than report ...

Apptad, Inc.

Senior AI Automation Engineer

Fort Mill, SC · On-site

$97K - $127K/yr

Job Title: Senior AI Automation Engineer Location: Fortmill, SC (Onsite) Duration: Contract ... Strong experience in Python development. * Hands-on experience with Generative AI, LLMs, and AI ...

AERONIX INC

Senior FPGA Design Engineer

Greenville, SC · On-site

$145K - $175K/yr

Senior FPGA Engineer Department: Engineering Reports To: Functional Team Lead / Program Manager ... Familiarity with revision control systems (Git/Bitbucket) and scripting in Python, TCL, or Linux ...

Forge Forward, Inc.

Engineer, Open

Charleston, SC · On-site

$120 - $150/hr

The Senior Cloud Engineer is a hands‑on, senior‑level technical role responsible for the design ... Develop and maintain automation using PowerShell, Bash, Python * Support DevSecOps pipelines ...

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Senior Python Engineer information

See South Carolina salary details

$51K

$131.7K

$181K

How much do senior python engineer jobs pay per year?

As of Sep 7, 2026, the average yearly pay for senior python engineer in South Carolina is $131,747.00, according to ZipRecruiter salary data. Most workers in this role earn between $112,700.00 and $151,700.00 per year, depending on experience, location, and employer.

What does a senior Python engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the key skills and qualifications needed to thrive as a senior Python engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What are the common challenges senior Python engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.

What are the most commonly searched types of Python Engineer jobs in South Carolina?

The most popular types of Python Engineer jobs in South Carolina are:

What are popular job titles related to Senior Python Engineer jobs in South Carolina?

For Senior Python Engineer jobs in South Carolina, the most frequently searched job titles are:

What job categories do people searching Senior Python Engineer jobs in South Carolina look for?

The top searched job categories for Senior Python Engineer jobs in South Carolina are:

What cities in South Carolina are hiring for Senior Python Engineer jobs?

Cities in South Carolina with the most Senior Python Engineer job openings:

Senior Python Engineer jobs near you
Infographic showing various Senior Python Engineer job openings in South Carolina as of August 2026, with employment types broken down into 92% Full Time, 4% Part Time, and 4% Contract. Highlights an 85% Physical, 5% Hybrid, and 10% Remote job distribution, with an average salary of $131,747 per year, or $63.3 per hour.

Senior DevSecOps Engineer with Security Clearance

INFORMATION SYSTEMS SOLUTIONS, INC

Charleston, SC • On-site

$109K - $149K/yr

Other

Medical, Retirement

Re-posted 9 days ago

Job description

Senior DevSecOps Engineer INFORMATION SYSTEMS SOLUTIONS, INC Senior DevSecOps Engineer Charleston, SC Description The Senior DevSecOps Engineer will support a Navy enterprise command-and-control environment in Charleston, SC. This position serves as a senior technical authority responsible for integrating cybersecurity practices into enterprise DevOps processes, enabling secure automation, continuous compliance, and resilient infrastructure operations within classified DoD networks. The selected candidate will drive DevSecOps strategy and standards, embeds security and compliance across the delivery lifecycle, and partners with application, infrastructure, security, and data teams to enable scalable, resilient, and secure cloud solutions. This position is 100% onsite. Specific duties include but are not limited to the following: · Provide DevSecOps leadership and sustainment support for enterprise cloud on premises computing environments. · Perform lifecycle management activities including platform upgrades, regression testing, version management, patching, and production deployments following change management processes  · Support multi-platform service architectures across on premises environments  · Develop and maintain architecture documentation, deployment guides, installation configuration guides, network boundary diagrams, and security artifacts  · Support DoD RMF activities, IAVA remediation, DISA STIG implementation, continuous monitoring, and Authority to Operate (ATO) packages  · Provide 24x7 Tier 3 operational support for production environments  · Analyze architectures to identify opportunities for optimization, automation, efficiency improvements, and cost reduction Why Work For ISS? At ISS we pride ourselves on providing an employee-focused and family-first environment. As a small business, we take the time to know our employees and have a vested interest in helping them achieve their career goals. We foster teamwork through regular company events and encourage professional development through training and education opportunities. ISS values its employees by providing a comprehensive benefits package that includes a fully vested 401(k) matching program, coverage of family medical deductibles, spot bonuses, and educational assistance to further your career. Requirements Clearance Level Top Secret  Certifications (IAT Level II) One of the following: · CompTIA Security+ · CompTIA CySA+ · CCNA Security · GSEC · GICSP · SSCP And
• Operating System Certificate (e.g., Linux+, Windows Server, CCNA, etc.) Required Skills · Seven (7) years of experience in DevOps engineering, DevSecOps engineering, cloud engineering, cybersecurity engineering, or enterprise systems engineering  · Experience designing, implementing, and maintaining secure automation solutions within enterprise environments  · Strong experience developing automation scripts using PowerShell, Python, Bash, or similar scripting languages  · Experience integrating security testing, vulnerability scanning, compliance validation, and automated security controls into DevOps workflows  · Experience administering enterprise Windows and Linux environments  · Experience supporting virtualization platforms including VMware vSphere, ESXi, and vCenter  · Experience implementing monitoring, logging, alerting, and operational visibility solutions  · Experience supporting secure DoD, government, or highly regulated environments  · Strong understanding of cybersecurity principles, vulnerability management, secure architecture, and system hardening practices  · Experience supporting Risk Management Framework (RMF), NIST cybersecurity frameworks, DISA STIG implementation, continuous monitoring, and Authority to Operate (ATO) activities

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