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Senior Python Engineer Jobs in South Carolina (NOW HIRING)

TRULEO

Senior Software Engineer

Greenville, SC

$115K - $151K/yr

The Role We're hiring a Senior Software Engineer to join our engineering team in Greenville, SC, on ... Experience with Python, machine learning (ML), ML Ops * Experience building AI-powered systems.

Forge Forward, Inc.

Be Seen First

Senior Infrastructure & Platform Engineer

Charleston, SC · On-site

$110K - $135K/yr

Forge Forward is searching for a Senior Infrastructure & Platform Engineer to support a client in ... Proficiency in scripting/programming (Python, PowerShell, Bash) * Experience with Git-based version ...

Attain Finance

Senior Site Reliability Engineer

Greenville, SC · On-site +1

$53.50 - $71.25/hr

Apply today and take the next step in your career with Attain Finance! We're looking for a Senior ... Work across AWS, EKS, ArgoCD, Helm, GitHub Actions, Azure DevOps, Terraform, and Python. * Fix the ...

Attain Finance

Senior Site Reliability Engineer

Greenville, SC · On-site

$53.50 - $71.25/hr

Apply today and take the next step in your career with Attain Finance! We're looking for a Senior ... Work across AWS, EKS, ArgoCD, Helm, GitHub Actions, Azure DevOps, Terraform, and Python. * Fix the ...

Attain Finance

Senior Site Reliability Engineer

Greenville, SC · On-site

$53.50 - $71.25/hr

Apply today and take the next step in your career with Attain Finance! We're looking for a Senior ... Work across AWS, EKS, ArgoCD, Helm, GitHub Actions, Azure DevOps, Terraform, and Python. * Fix the ...

Anveta Inc

Senior DevOps Engineer (AI Platform)

Fort Mill, SC · On-site

$114K - $146K/yr

Senior DevOps Engineer (AI Platform) Location: Fort Mill, SC (Hybrid - 3 Days Onsite) Job Type ... Proficiency in scripting using Python and/or Shell (Bash) . * Strong understanding of networking ...

Itron, Inc

Sr. Manufacturing Engineer

West Union, SC · Hybrid

$77K - $105K/yr

We are seeking a Senior Manufacturing Engineer - New Product Introduction (NPI) to play a critical ... Data analysis and tools (Excel, Power BI, SQL, Python) * PLM, ERP, MES systems; Minitab/JMP; Visio ...

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Senior Python Engineer information

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$51K

$131.7K

$181K

How much do senior python engineer jobs pay per year?

As of Jul 19, 2026, the average yearly pay for senior python engineer in South Carolina is $131,747.00, according to ZipRecruiter salary data. Most workers in this role earn between $112,700.00 and $151,700.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Python Engineer, and why are they important?

To thrive as a Senior Python Engineer, you need expert knowledge of Python programming, software architecture, and experience with web frameworks, supported by a degree in computer science or related field. Familiarity with tools like Django, Flask, REST APIs, Docker, and version control systems such as Git is typically required, along with possible certifications in cloud technologies or Python itself. Strong problem-solving abilities, leadership, and effective communication skills help you lead teams and collaborate across departments. These skills ensure robust, scalable software solutions and foster innovation and efficiency within development projects.

What does a Senior Python Engineer do?

A Senior Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often take on leadership roles within development teams, contribute to architectural decisions, and mentor junior engineers. Senior Python Engineers work on complex projects, ensure code quality, and help implement best practices to improve efficiency and reliability. Their work may span back-end development, data engineering, automation, and integrating with other technologies.

What are the common challenges Senior Python Engineers face when leading projects, and how can they effectively address them?

Senior Python Engineers often encounter challenges such as balancing hands-on coding with overseeing project architecture, mentoring junior developers, and ensuring code quality across the team. Effectively addressing these challenges involves strong communication, setting clear coding standards, and fostering a collaborative environment through regular code reviews and knowledge-sharing sessions. Staying updated on best practices and leveraging automation tools for testing and deployment can also help streamline workflows and maintain high-quality deliverables.
What are the most commonly searched types of Python Engineer jobs in South Carolina? The most popular types of Python Engineer jobs in South Carolina are:
What are popular job titles related to Senior Python Engineer jobs in South Carolina? For Senior Python Engineer jobs in South Carolina, the most frequently searched job titles are:
What job categories do people searching Senior Python Engineer jobs in South Carolina look for? The top searched job categories for Senior Python Engineer jobs in South Carolina are:
What cities in South Carolina are hiring for Senior Python Engineer jobs? Cities in South Carolina with the most Senior Python Engineer job openings:
Senior Python Engineer jobs near you
Infographic showing various Senior Python Engineer job openings in South Carolina as of July 2026, with employment types broken down into 90% Full Time, 6% Part Time, 3% Contract, and 1% Nights. Highlights an 87% Physical, 4% Hybrid, and 9% Remote job distribution, with an average salary of $131,747 per year, or $63.3 per hour.

Senior Software Engineer

TRULEO

Greenville, SC

$115K - $151K/yr

Full-time

Re-posted 9 days ago

Job description

About TRULEO

TRULEO builds the first case intelligence platform for law enforcement, and more than 1,000 agencies use us today. Most departments already have the information they need to solve a case, but it's spread across RMS, CAD, jail calls, body-worn camera footage, OSINT, and a dozen other systems that don't talk to each other, and Detectives don't have time to dig through all of it.

TRULEO sits on top of the systems an agency already uses and works the case alongside its detectives. It searches across those sources, connects related information, and surfaces leads in minutes instead of weeks. We don't replace their systems, but we make the data an agency already owns easier to actually use, so investigators can spend their time closing cases instead of running queries.

TRULEO has helped agencies turn thousands of files into real leads, break open cold cases, and solve crimes in real time. And we're hiring engineers to help us bring case intelligence to more departments.

The Role

We're hiring a Senior Software Engineer to join our engineering team in Greenville, SC, on-site. This is a full-stack engineering role. You'll work across React, Node/TypeScript, and PostgreSQL data models. Because our product is AI-driven, you'll also build and improve the agentic systems that make TRULEO useful to detectives. It's a high-ownership role on a small, senior team where you'll ship features end to end, from design through production, and your work will directly shape how cases get solved.

What You'll Do
  • Build and ship customer-facing features across the full stack (front end, back end, and data), and own them from design through production.
  • Design and maintain the APIs and data models behind our core case-intelligence workflows.
  • Develop and improve our AI capabilities
  • Build and maintain the connectors that ingest, organize, and cross-reference data from the third-party systems detectives rely on.
  • Run what you build in production, including the harder parts of rollout - migrations, backfills, feature flags, and debugging live systems.
  • Work within our secure, compliant development process (SOC 2, FBI CJIS) and partner with Product to turn customer needs into features people actually use.
Qualifications
  • 7+ years of professional software engineering experience.
  • Strong full-stack background, with production experience in React, TypeScript, Node.js, and PostgreSQL.
  • Experience with Python, machine learning (ML), ML Ops
  • Experience building AI-powered systems.
  • Comfortable with cloud infrastructure and containerized deployments.
  • A practical, self-directed engineer who communicates clearly and does well on a small team where everyone wears several hats.
  • Able to work on-site in Greenville, SC, and to pass the background check required to work with criminal justice (CJIS) data.
Employment Type: FULL_TIME

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