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Senior Python Developer Jobs in Lexington, SC (NOW HIRING)

Integer

Software Engineer

Columbia, SC · On-site

Implement and oversee DevOps methodologies to ensure software integrity, maintainability, and ... For example: Java, C++, C#, Objective C, Python, SQL, Rust, Perl, Go, REST API, or Bash.

Integer Technologies

Software Engineer

Columbia, SC · On-site

$120 - $160/hr

Implement and oversee DevOps methodologies to ensure software integrity, maintainability, and ... Java, C++, C#, Objective C, Python, SQL, Rust, Perl, Go, REST API, or Bash. * Demonstrated ...

New

Job Board

Professional Services Engineer

North, SC · On-site

We are currently seeking a Professional Services Engineer, reporting to the Sr. Manager of ... Scripting in (some of) Zeek, Bash, Python, Perl, Powershell, etc. * Strong briefing skills ...

IGH ICW GROUP HOLDINGS, INC.

Applied AI Engineer

Kneece, SC · On-site

$121.62 - $217.71/hr

Support senior engineers in AI architecture reviews, code reviews, and operationalization planning ... Proficiency in Python and ML frameworks such as PyTorch, TensorFlow, or Hugging Face Transformers.

New

Td

Data Scientist III - FCRM

Lexington, SC · On-site

$96K - $155K/yr

Position typically deals with senior/executive management * Works independently on activities ... Uses a wide range of programing languages (e.g. Python) and techniques for extracting and preparing ...

Armis Security

AI Solutions Consultant

North, SC · On-site

Reporting to the SVP of Strategic Initiatives, this team designs and ships AI-native solutions ... We're looking for engineers fluent in modern AI application development - agent frameworks ...

Artefact

Data Consultant - Junior (New)

North, SC · On-site

Analyzing data using tools such as Excel, SQL, Python, or R to surface trends, patterns, and ... senior client. You're the kind of person who asks "why?" before jumping to "how," and you never ...

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Senior Python Developer information

See Lexington, SC salary details

$47.1K

$121.5K

$166.9K

How much do senior python developer jobs pay per year?

As of Aug 21, 2026, the average yearly pay for senior python developer in Lexington, SC is $121,525.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,000.00 and $139,900.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

Are senior Python developers still in demand?

Senior Python developers remain in high demand due to the language's versatility in web development, data analysis, machine learning, and automation. Companies seek experienced developers with skills in frameworks like Django or Flask, and proficiency in cloud platforms and APIs enhances job prospects.

How much does a senior Python developer make?

A senior Python developer typically earns between $100,000 and $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may hold certifications or advanced degrees that influence salary levels.

What does a senior Python developer do?

A senior Python developer designs, develops, and maintains complex software applications using Python. They often lead projects, review code, optimize performance, and collaborate with cross-functional teams, requiring strong problem-solving skills and knowledge of frameworks like Django or Flask. Additionally, they may mentor junior developers and ensure code quality through testing and best practices.

What are the most commonly searched types of Python Developer jobs in Lexington, SC?

The most popular types of Python Developer jobs in Lexington, SC are:

What are popular job titles related to Senior Python Developer jobs in Lexington, SC?

For Senior Python Developer jobs in Lexington, SC, the most frequently searched job titles are:

What job categories do people searching Senior Python Developer jobs in Lexington, SC look for?

The top searched job categories for Senior Python Developer jobs in Lexington, SC are:

What cities near Lexington, SC are hiring for Senior Python Developer jobs?

Cities near Lexington, SC with the most Senior Python Developer job openings:

Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in Lexington, SC as of August 2026, with employment types broken down into 1% Internship, 87% Full Time, 4% Part Time, and 8% Contract. Highlights an 81% Physical, 5% Hybrid, and 14% Remote job distribution, with an average salary of $121,525 per year, or $58.4 per hour.

Software Engineer

Integer

Columbia, SC • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 28 days ago

Integer Holdings rating

7.5

Company rating: 7.5 out of 10

Based on 43 frontline employees who took The Breakroom Quiz

263rd of 543 rated manufacturers

Job description

About the role
This Software Engineer role will be focused on developing software tools supporting system design, development, and manufacturing for customers in the defense, and aerospace, and maritime industries. Key objectives for the role are:
  1. Develop modeling and simulation software tools for use in design and manufacturing environments.
  1. Research and integrate emerging computational tools and workflows, including AI/ML technologies and modern data architectures, with physics-based modeling and simulation.
  1. Collaborate across disciplines and with university partners to build prototypes that demonstrate technical capabilities applied to design and manufacturing systems with DoW relevance.
  1. Mature prototype capabilities into production-ready enterprise applications supporting the defense industrial base.

What you'll do
  • Agentic Architecture Development: Support research and development of autonomous software agents, deployed in the control of complex systems.
  • Architectural Design & Documentation: Develop and document robust technical solutions for unique problem sets, ensuring scalable and maintainable software architectures and promoting standardization and re-use of modular code.
  • Software Development & Automation: Write clean, efficient code; adapt existing frameworks; and develop pipelines that optimize development processes and drive tangible results.
  • Product Development: Leverage hands-on software development experience to create innovative software products for internal teams and external customers, using proven methodologies from past projects.
  • Data Integration Strategy: Develop and implement methods for integrating data from multiple sources-ranging from design information to transactional and streaming data-to create unified, actionable insights.
  • Software Quality Management through DevOps Practices: Implement and oversee DevOps methodologies to ensure software integrity, maintainability, and scalability. Utilize version control systems (e.g., Git) for source code management, enforce CI/CD pipelines for automated testing and deployment, and apply infrastructure-as-code principles to enhance operational efficiency.
  • Automated Workflow & Cross-Functional Collaboration: Build automated workflows to streamline data and software operations, while collaborating with cross-functional teams including data scientists, engineers, and domain specialists to ensure software solutions align with business needs.
  • Technical & Non-Technical Presentations: Present and clearly articulate architectural solutions to both technical teams and non-technical stakeholders, ensuring alignment and understanding across all levels.
  • Technical Research & Documentation: Conduct research, review technical documentation, and evaluate the pros and cons of emerging technologies to continuously refine engineering strategies.
  • Stakeholder Communication: Translate complex software functions and development requirements into clear, accessible terms for customers, government representatives, project managers, and other non-technical stakeholders.

Qualifications
  • Must be a U.S. Citizen with the ability to obtain and maintain a DoW Secret Clearance (eligibility for Top Secret is a plus).
  • Bachelor's degree in Computer Science, Software/Computer Engineering or related field.
  • 5+ years of professional experience in software development related to modeling, simulation, design, or manufacturing applications.
  • Experience with middleware software languages and technologies. For example: Java, C++, C#, Objective C, Python, SQL, Rust, Perl, Go, REST API, or Bash.
  • Experience with frontend software languages and technologies. For example: Angular, React, Swift, TypeScript, JavaScript, Vue, Cordova or Node
  • Demonstrated proficiency in developing software products for deployment in a defense environment.
  • Demonstrated proficiency in AI and ML technologies, including modeling, and machine learning frameworks (TensorFlow, PyTorch, or Scikit-learn) to enhance system efficiency.
  • Demonstrated proficiency in designing and documenting scalable technical solutions, including microservices, cloud-based architectures, and modular frameworks.
  • Proficiency in building systems utilizing simultaneous data streams from real-world equipment and/or simulations such as Digital Twins.
  • Hands-on experience with DevOps practices, including CI/CD pipelines, automated testing, containerization (Docker/Kubernetes), and version control systems (Git).
  • Experience mentoring junior developers, conducting peer code reviews, and contributing to a knowledge-sharing culture.
  • Excellent problem-solving skills and attention to detail.
  • Excellent written and verbal communication skills; ability to produce clear technical reports and give concise briefings to senior military and executive stakeholders.

Additional Desired Qualifications
  • Masters or PhD in a relevant engineering or computer science discipline.
  • Experience with Systems Engineering and Systems Integration.
  • Experience in development of computation design applications.
  • Experience in manufacturing environments.
  • Experience using modeling and simulation tools in the development and optimization of components and systems, such as FEA, CFD, Discrete-event Simulation.
  • Experience in developing and maintaining enterprise software in production.
  • Experience developing and running applications on HPCs.

What We Do
Integer Technologies is an applied research and product development company founded by scientists and engineers with a passion for protecting freedom with innovation. We perform R&D on next-generation systems and technologies for the Department of Defense and other U.S. Government agencies. We are hardware and software developers with experience transforming research into fieldable technology. Our core portfolio of research includes projects in power & energy systems, unmanned systems (with an emphasis on maritime systems), digital engineering, cyber security, and advanced manufacturing. Our mission is to create a safer world by translating scientific discoveries into reliable products that address urgent national security needs... at the speed of relevance.
Compensation and Benefits
  • Base salary which exceeds local & national industry averages.
  • Integer fully covers medical, prescription, vision, and dental insurance costs for the employee and dependents. Integer's standard plan pays 100% of health insurance premiums for your entire family from a well-known national insurer, saving employees thousands of dollars annually.
  • Year-end performance-based bonuses.
  • 401(k) with company matching that vest immediately; no funny business.
  • Paid vacation.
  • Paid sick leave.
  • Paid holidays.
  • Relocation assistance available.

Company Perks
  • Startup culture with the stability of a large company. Integer's business plan has years of time phased contracted work, alleviating the would-be risk from a traditional small company.
  • Direct access to company leadership, prioritization of people over process, and a stellar team with a shared desire for personal and professional growth.
  • Friendly atmosphere where people enjoy not only their work and what they are creating but enjoy helping each other as well.
  • Bottomless coffee.

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