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Senior Python Developer Jobs in Houston, TX (NOW HIRING)

AMSYS Talent

LLM Infrastructure Engineer

Houston, TX · On-site

We are looking for a Senior Python / AI API Engineer to build and deploy production-grade services powering Large Language Model (LLM) applications. This role focuses on developing high-performance ...

IMC Associates

SW & Eng Mgr Python

Houston, TX · On-site +1

Python: Sr. Software Engineer and Engineering Managers Locations: NYC, Texas - Each Position Can Be On Site, Partially or 100% Remote 115k - 185K base with some flex - Fulltime Depending On ...

RIT Solutions, Inc.

Palantir Developer

Spring, TX · On-site

RIT Solutions, Inc. is seeking a Senior Data Engineer specializing in Python and Palantir to join the CCS100 Fusion Team. The role involves optimizing investment and operational decisions by ...

ComboCurve, Inc.

Senior Software Engineer, Python

Houston, TX · On-site +1

$117K - $154K/yr

Improve CI/CD pipelines, testing practices, and developer experience across the platform. * Partner ... Advanced Python Proficiency: Deep expertise in Python 3.13+, specifically utilizing type ...

NAVA Software Solutions

Sr Data Developer

Houston, TX · On-site

Senior Data Developer Location: Houston TX - 2 days/week hybrid Type: Full time/Direct Hire As the ... Python: 5 years (Preferred) * BI Tools (Sigma Computing, Tableau, Power BI, etc): 4 Years ...

CEDENT

DB2 SQL Data Engineer

Houston, TX · On-site

... Python, microservices, and VS Code IDE. Responsibilities: * Develop and maintain SQL stored ... Proven track record as a Senior Database Developer with a focus on DB2 database development in IBM ...

Cedent

DB2 SQL Data Engineer (Houston, TX)

Houston, TX · On-site

... Python, microservices, and VS Code IDE. Responsibilities: * Develop and maintain SQL stored ... Proven track record as a Senior Database Developer with a focus on DB2 database development in IBM ...

SmartIPlace

Senior Developer - SQL/ Oracle

Houston, TX · On-site

Senior Developer - SQL/ Oracle. * Requires candidate to be a US Citizen or GC holder. * Long term ... Python development experience with db libraries and interfaces to ETL data. * Experience with ...

Converge Resources

Senior Maximo Developer

Houston, TX · On-site +1

$91K - $126K/yr

Senior IBM Maximo Developer Position Overview An energy infrastructure company is hiring a Senior ... Develop automation scripts using Python/Jython and other supported scripting technologies. Build ...

Kunai

Senior Software Engineer (Python)

Houston, TX · On-site

$117K - $154K/yr

This is a hands-on engineering team: our core focus is building software, not managing vendor ... Python code as the primary language for new services - Incorporate AI-assisted development ...

Kunai

Senior Software Engineer (Python)

Houston, TX · On-site

$117K - $154K/yr

This is a hands-on engineering team: our core focus is building software, not managing vendor ... Python code as the primary language for new services - Incorporate AI-assisted development ...

Kunai

Senior Software Engineer (Python)

Houston, TX · On-site

$117K - $154K/yr

This is a hands-on engineering team: our core focus is building software, not managing vendor ... Python code as the primary language for new services - Incorporate AI-assisted development ...

Forthea

Senior Software Developer

Houston, TX · On-site +1

$52 - $68.75/hr

Forthea is seeking a Senior Software Developer to join our team and help build and evolve our ... Design and develop robust, scalable backend services using Python and Node.js, primarily data ...

Forthea

Senior Software Developer

Houston, TX · On-site

$52 - $68.75/hr

Forthea is seeking a Senior Software Developer to join our team and help build and evolve our ... Design and develop robust, scalable backend services using Python and Node.js, primarily data ...

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Senior Python Developer information

See Houston, TX salary details

$52.5K

$135.6K

$186.2K

How much do senior python developer jobs pay per year?

As of Aug 6, 2026, the average yearly pay for senior python developer in Houston, TX is $135,583.00, according to ZipRecruiter salary data. Most workers in this role earn between $116,000.00 and $156,100.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

How much does a senior Python developer make?

A senior Python developer's salary typically ranges from $100,000 to $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may have certifications or experience with cloud platforms, which can influence compensation.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.
What are the most commonly searched types of Python Developer jobs in Houston, TX? The most popular types of Python Developer jobs in Houston, TX are:
What are popular job titles related to Senior Python Developer jobs in Houston, TX? For Senior Python Developer jobs in Houston, TX, the most frequently searched job titles are:
What job categories do people searching Senior Python Developer jobs in Houston, TX look for? The top searched job categories for Senior Python Developer jobs in Houston, TX are:
What cities near Houston, TX are hiring for Senior Python Developer jobs? Cities near Houston, TX with the most Senior Python Developer job openings:
Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in Houston, TX as of July 2026, with employment types broken down into 1% Internship, 88% Full Time, 6% Part Time, and 5% Contract. Highlights an 84% Physical, 4% Hybrid, and 12% Remote job distribution, with an average salary of $135,583 per year, or $65.2 per hour.

LLM Infrastructure Engineer

AMSYS Talent

Houston, TX • On-site

Full-time

Re-posted 7 days ago

Job description

We are looking for a Senior Python / AI API Engineer to build and deploy production-grade services powering Large Language Model (LLM) applications. This role focuses on developing high-performance APIs for model inference, optimizing GPU workloads, and deploying AI services in cloud environments.
This is an engineering-focused role, not research. We are looking for someone who has built and shipped AI systems into production and understands the challenges of scalable inference and model serving.
Key Responsibilities
  • Develop high-performance APIs using Python (3.10+) and FastAPI
  • Build and deploy LLM inference services using HuggingFace Transformers and PyTorch
  • Optimize GPU workloads and CUDA memory usage
  • Implement streaming inference APIs for real-time model responses
  • Containerize and deploy services using Docker and GPU-enabled infrastructure
  • Deploy AI workloads in Azure environments (AKS, ACI, or Container Apps)

Required Skills
  • Strong Python development experience (3.10+)
  • Hands-on experience building production APIs with FastAPI
  • Experience with HuggingFace Transformers and PyTorch
  • Solid understanding of REST API design
  • Experience deploying containerized applications with Docker

Nice to Have
  • Experience with OpenAI-compatible APIs, vLLM, or Text Generation Inference (TGI)
  • Experience deploying AI workloads on Azure GPU infrastructure
  • Familiarity with LoRA / PEFT fine-tuning
  • Exposure to legal or financial NLP use cases

Ideal Candidate: A hands-on engineer who understands how LLM systems run in production-from model loading and tokenization to GPU deployment and scalable APIs.

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