ZipRecruiter

Log In

1

Senior Python Developer Jobs in Massachusetts (NOW HIRING)

Sonoma Consulting Inc.

Senior DevOps Engineer

Boston, MA · On-site

$141K - $181K/yr

TITLE : DevOps Engineer/Senior DevOps Engineer LOCATION : We are looking forcandidates in 1. Boston ... Experience coding or scripting with Shell, Ruby/JRuby, Perl, Python, Powershell, Java, Go, or Bash

Judge Group, Inc.

Senior AWS Developer

Quincy, MA · On-site

$54 - $64/hr

  • Medical

The Sr. AWS Developer's primary role is to support the design and development of a serverless ... AWS Lambda (Python runtime) * AWS Step Functions * API Gateway (REST/HTTP APIs) * Amazon Cognito

Medtronic

Sr. Software DevOps Engineer

Newton, MA · On-site

$142K - $183K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

As a Sr. Software DevOps Engineer, you will play a pivotal role in accelerating our software ... Proficient in languages such as Python, C++, Bash, or similar * Extensive experience with ...

Medtronic

Sr. Software DevOps Engineer

Newton, MA · On-site

$142K - $183K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

As a Sr. Software DevOps Engineer, you will play a pivotal role in accelerating our software ... Proficient in languages such as Python, C++, Bash, or similar * Extensive experience with ...

Saviance

Senior Java/AWS Engineer -with LIMS

Boston, MA · On-site

$135K - $178K/yr

They are seeking a skilled Senior Java/AWS Engineer -with LIMS to collaboratively solve complex ... Some Python programming is preferred Company : Saviance is a modern consulting firm providing a ...

previous page

Showing results 41-60

All JobsPython Developer JobsSenior Python Developer JobsSenior Python Developer Jobs in Massachusetts

Senior Python Developer information

See Massachusetts salary details

$60.1K

$155.1K

$213K

How much do senior python developer jobs pay per year?

As of Aug 20, 2026, the average yearly pay for senior python developer in Massachusetts is $155,055.00, according to ZipRecruiter salary data. Most workers in this role earn between $132,700.00 and $178,600.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

Are senior Python developers still in demand?

Senior Python developers remain in high demand due to the language's versatility in web development, data analysis, machine learning, and automation. Companies seek experienced developers with skills in frameworks like Django or Flask, and proficiency in cloud platforms and APIs enhances job prospects.

How much does a senior Python developer make?

A senior Python developer typically earns between $100,000 and $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may hold certifications or advanced degrees that influence salary levels.

What does a senior Python developer do?

A senior Python developer designs, develops, and maintains complex software applications using Python. They often lead projects, review code, optimize performance, and collaborate with cross-functional teams, requiring strong problem-solving skills and knowledge of frameworks like Django or Flask. Additionally, they may mentor junior developers and ensure code quality through testing and best practices.

What are the most commonly searched types of Python Developer jobs in Massachusetts?

The most popular types of Python Developer jobs in Massachusetts are:

What are popular job titles related to Senior Python Developer jobs in Massachusetts?

For Senior Python Developer jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Senior Python Developer jobs in Massachusetts look for?

The top searched job categories for Senior Python Developer jobs in Massachusetts are:

What cities in Massachusetts are hiring for Senior Python Developer jobs?

Cities in Massachusetts with the most Senior Python Developer job openings:

What are popular job titles related to Senior Python Developer jobs in MA?

For Senior Python Developer jobs in MA, the most frequently searched job titles are:

Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in Massachusetts as of August 2026, with employment types broken down into 1% Internship, 89% Full Time, 5% Part Time, and 5% Contract. Highlights an 76% Physical, 7% Hybrid, and 17% Remote job distribution, with an average salary of $155,055 per year, or $74.5 per hour.

Senior AI Engineer (Generative AI & Agentic Systems)

Pan.bio

Boston, MA • On-site

$180 - $260/hr

Other

Posted 2 days ago

New

Job description

Now Hiring Machine Learning AI Engineering Priority Hire

Senior AI Engineer (Generative AI & Agentic Systems)About Pan.Bio

Pan.Bio is building an AI-native platform that helps scientists and clinicians analyze complex biomedical data, automate research workflows, and accelerate discovery. Our products combine bioinformatics, cloud computing, and Generative AI to transform how researchers interact with data, knowledge, and scientific workflows.

We are looking for a Senior AI Engineer with strong machine learning and data science fundamentals to help build the next generation of AI-powered capabilities across our platform.

What You'll Do
  • Design, build, and deploy production-grade AI systems and intelligent applications.
  • Develop AI agents, agent skills, MCP integrations, RAG systems, and workflow automation solutions.
  • Build reusable AI capabilities that can be shared across products and use cases.
  • Evaluate, monitor, and improve AI systems using rigorous experimentation and data-driven decision making.
  • Collaborate closely with software engineers, bioinformaticians, and product teams to solve real-world scientific and healthcare challenges.
  • Stay current with advances in Generative AI and help shape our technical roadmap.
What We're Looking For
  • 4+ years of experience in AI/ML Engineering, Data Science, Applied AI, or a related field.
  • Strong foundation in machine learning, statistics, experimentation, and data analysis.
  • Strong Python programming and software engineering skills.
  • Experience building and deploying production AI/ML systems in cloud environments (GCP preferred).
  • Hands-on experience with LLMs, reasoning models, tool calling, structured outputs, context engineering, and AI evaluation.
  • Experience building agentic AI systems, including AI agents, agent skills, MCP integrations, RAG, and workflow automation.
  • Familiarity with the full ML lifecycle, from experimentation and evaluation to deployment and monitoring.
  • Ability to thrive in a fast-paced startup environment with high ownership and autonomy.
Nice to Have

Not blockers, but they'll make your application stand out.

  • Experience with multi-agent systems, agent orchestration, or AI platform engineering.
  • Experience with AI observability, guardrails, and governance.
  • Experience with Docker, Kubernetes, MLOps, and CI/CD.
  • Background in bioinformatics, genomics, healthcare, life sciences, or scientific computing.
Why Join Pan.Bio?
  • Build cutting-edge AI products at the intersection of Generative AI and life sciences.
  • Work on challenging problems with real-world scientific and healthcare impact.
  • Join a small, experienced team with significant ownership and influence over product direction.
  • Help shape the future of AI-powered scientific discovery.
#J-18808-Ljbffr

Apply