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Senior Python Data Science Jobs in Massachusetts

Compass

Senior Lead Data Scientist

Boston, MA

$204K - $226K/yr

Deep expertise in multiple complex data science areas, such as XGBoost, deep learning, and NLP ... Mastery of advanced Python and SQL for large-scale data manipulation, analysis, and architectural ...

Saviance

Senior Data Science Engineer

Cambridge, MA · On-site

$126K - $151K/yr

As a Senior Data Science Engineer, you will leverage radar data to drive strategic decisions ... Required : • Proficiency in programming languages such as Python, R, or Matlab. • Experience ...

Pwc

AIT - AI Data Scientist Manager

Boston, MA · On-site

$99K - $297K/yr

... Python, data science libraries, model validation methods, and modern AI/ML approaches, including generative AI where relevant, to communicate actionable insights to business and technical ...

Triveni Bio

Director, AI and Data Science

Watertown, MA · On-site

$240K - $255K/yr

... a Python script, and who thrives in a fast-paced biotech environment where no two weeks look the ... scientists to senior leaders * Self-starter mindset: Comfortable with ambiguity; able to ...

Triveni Bio

Director, AI and Data Science

Watertown, MA · On-site

$240K - $255K/yr

... a Python script, and who thrives in a fast-paced biotech environment where no two weeks look the ... scientists to senior leaders * Self-starter mindset: Comfortable with ambiguity; able to ...

ShiftCode Analytics, Inc.

Data Science Engineer

Boston, MA · On-site

$124K - $149K/yr

ShiftCode Analytics, Inc. is seeking a talented Data Science Engineer to join their team and ... sources. • Utilize Python and Spark for data preprocessing, feature engineering, and model ...

Gradient AI

Staff Data Scientist

Boston, MA · On-site +1

$160K - $195K/yr

Advanced proficiency with deep learning frameworks and the core Python data science ecosystem, and a deep understanding of modern AI architectures (e.g., Transformers, Neural Networks, LLMs) and ...

MANTECH

Senior Data Scientist

Springfield, MA

Apply expert knowledge of industry-standard data science principles to identify anomalous events ... Java and Python. Demonstrated ability to use Share Point, Tableau, Redmine, and other systems ...

MANTECH

Senior Data Scientist

Springfield, MA

Apply expert knowledge of industry-standard data science principles to identify anomalous events ... Java and Python. Demonstrated ability to use Share Point, Tableau, Redmine, and other systems ...

Dell GmbH

Senior Advisor, Data Science

Hopkinton, MA · On-site

$150 - $200/hr

Senior Advisor, Data Science Data Science Senior Advisor (Taxonomy, Ontology, and Governance) Data Science is all about breaking new ground to enable businesses to answer their most urgent questions.

Formation Bio

Director, Data Science

Boston, MA · On-site

$235K - $307K/yr

Present complex analytical findings to senior stakeholders, including executive leadership About ... Strong programming skills, particularly in Python * Extensive experience in multi-modal ...

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Senior Python Data Science information

What is the difference between Senior Python Data Science vs Data Analyst?

AspectSenior Python Data ScienceData Analyst
Required SkillsPython, machine learning, statistical analysis, data modelingExcel, SQL, data visualization, basic statistics
Work EnvironmentData science teams, R&D, product developmentBusiness units, reporting, operational analysis
Industry UsageTech, finance, healthcare, e-commerceRetail, marketing, finance, healthcare

Senior Python Data Scientists focus on advanced analytics, machine learning, and building predictive models using Python, often working in R&D or product teams. Data Analysts primarily handle data reporting, visualization, and basic statistical analysis to support business decisions. While both roles require data handling skills, Senior Python Data Science roles demand deeper technical expertise and experience with complex algorithms.

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Senior Python Data Science jobs near you
Infographic showing various Senior Python Data Science job openings in Massachusetts as of August 2026, with employment types broken down into 1% As Needed, 80% Full Time, 14% Part Time, 1% Temporary, 3% Contract, and 1% Nights. Highlights an 84% Physical, 4% Hybrid, and 12% Remote job distribution.

Senior Data Scientist

Motion Recruitment Partners, LLC

Boston, MA • On-site

Other

Re-posted 6 days ago

Job description


Join a cutting-edge AI Platform team as a Senior Data Scientist in a 6-month remote contract-to-hire opportunity. You'll help develop enterprise-scale AI solutions leveraging Large Language Models (LLMs), Retrieval-Augmented Generation (RAG), Agentic AI, NLP, machine learning, and distributed AI architectures to support complex research, document intelligence, and workflow automation systems.
This role offers the opportunity to work on some of the most advanced AI challenges in industry today. The team is building next-generation intelligent systems that combine LLMs, retrieval technologies, and autonomous agents to solve highly complex information and decision-making problems. They're looking for someone who can drive innovation, shape AI strategy, and help bring cutting-edge research into production.
Contract Duration: 6 Months (Contract-to-Hire)
Required Skills & Experience
Bachelor's degree required; Master's degree preferred
5-8+ years of experience in Data Science, Machine Learning, or Applied AI
Strong experience with Large Language Models (LLMs) and Generative AI applications
Hands-on experience designing and deploying RAG systems
Expertise in machine learning, NLP, and information retrieval techniques
Experience building and deploying production AI/ML systems
Strong Python programming skills
Experience working with distributed systems and cloud-based AI environments
Understanding of agentic AI architectures and autonomous workflows
Strong analytical, communication, and problem-solving skills
Desired Skills & Experience
Experience building enterprise-scale AI platforms
Familiarity with vector databases and semantic search technologies
Knowledge of legal, regulatory, or document-intensive data environments
Experience with model evaluation, monitoring, and optimization
Exposure to workflow automation and intelligent agent frameworks
Experience collaborating across data science, engineering, and product teams
Advanced degree in Data Science, Computer Science, Machine Learning, or a related field
What You Will Be Doing
Tech Breakdown
40% LLMs, RAG, and Generative AI
30% Machine Learning & NLP
20% Agentic AI & Intelligent Automation
10% Distributed Systems & Platform Collaboration
Daily Responsibilities
75% Hands On
5% Management Duties
20% Team Collaboration

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